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Journal of periodontal & implant science v.40 no.3, 2010년, pp.105 - 110  
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Biological effects of a semiconductor diode laser on human periodontal ligament fibroblasts

Choi, Eun-Jeong    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Yim, Ju-Young    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Koo, Ki-Tae    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Seol, Yang-Jo    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Lee, Yong-Moo    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Ku, Young    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Rhyu, In-Chul    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Chung, Chong-Pyoung    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry   ); Kim, Tae-Il    (Department of Periodontology and Dental Research Institute, Seoul National University College of Dentistry  );
  • 초록

    Purpose: It has been reported that low-level semiconductor diode lasers could enhance the wound healing process. The periodontal ligament is crucial for maintaining the tooth and surrounding tissues in periodontal wound healing. While low-level semiconductor diode lasers have been used in low-level laser therapy, there have been few reports on their effects on periodontal ligament fibroblasts (PDLFs). We performed this study to investigate the biological effects of semiconductor diode lasers on human PDLFs. Methods: Human PDLFs were cultured and irradiated with a gallium-aluminum-arsenate (GaAlAs) semiconductor diode laser of which the wavelength was 810 nm. The power output was fixed at 500 mW in the continuous wave mode with various energy fluencies, which were 1.97, 3.94, and 5.91 $J/cm^2$ . A culture of PDLFs without laser irradiation was regarded as a control. Then, cells were additionally incubated in 72 hours for MTS assay and an alkaline phosphatase (ALPase) activity test. At 48 hours post-laser irradiation, western blot analysis was performed to determine extracellular signal-regulated kinase (ERK) activity. ANOVA was used to assess the significance level of the differences among groups (P $J/cm^2$ (P $J/cm^2$ energy fluency (P $J/cm^2$ energy fluency than in the control. Conclusions: The present study demonstrated that the GaAlAs semiconductor diode laser promoted proliferation and differentiation of human PDLFs.


  • 주제어

    Alkaline phosphatase .   Extracellular signal-regulated kinases .   Fibroblasts .   Periodontal ligament .   Semiconductor diode lasers.  

  • 참고문헌 (28)

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  • 최은정 (1)

    1. 2000 "임산부의 치주 질환 활성도와 조산과의 상관관계에 관한 연구" 대한치주과학회지 = The journal of Korean academy of periodontology 30 (1): 111~120    
  • Yim, Ju-Young (0)

  • Koo, Ki-Tae (19)

  • Seol, Yang-Jo (57)

  • 이용무 (85)

  • Ku, Young (115)

  • Chung, Chong-Pyoung (85)

  • 김태일 (74)

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