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The Korean journal of parasitology v.48 no.2 = no.146, 2010년, pp.175 - 177   SCIE
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Primaquine Administration after Falciparum Malaria Treatment in Malaria Hypoendemic Areas with High Incidence of Falciparum and Vivax Mixed Infection: Pros and Cons

Wilairatana, Polrat    (Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University   ); Tangpukdee, Noppadon    (Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University   ); Kano, Shigeyuki    (Department of Tropical Medicine and Malaria Research Institute, National Center for Global Health and Medicine (NCGM)   ); Krudsood, Srivicha    (Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University  );
  • 초록

    Mixed infections of Plasmodium falciparum and Plasmodium vivax is high (~ 30%) in some malaria hypoendemic areas where the patients present with P. falciparum malaria diagnosed by microscopy. Conventional treatment of P. falciparum with concurrent chloroquine and 14 days of primaquine for all falciparum malaria patients may be useful in areas where mixed falciparum and vivax infections are high and common and also with mild or moderate G6PD deficiency in the population even with or without subpatent vivax mixed infection. It will be possibly cost-effective to reduce subsequent vivax illness if the patients have mixed vivax infection. Further study to prove this hypothesis may be warranted.


  • 주제어

    Plasmodium falciparum .   Plasmodium vivax .   mixed infection .   primaquine.  

  • 참고문헌 (14)

    1. Luxemburger C, Ricci F, Nosten F, Raimond D, Bathet S, White NJ. The epidemiology of severe malaria in an area of low transmission in Thailand. Trans R Soc Trop Med Hyg 1997; 91: 256-262. 
    2. Ministry of Public Health, Thailand, 2009 (unpublished data). 
    3. Looareesuwan S, White NJ, Chittamas S, Bunnag D, Harinasuta T. High rate of Plasmodium vivax relapse following treatment of falciparum malaria in Thailand. Lancet 1987; 2: 1052-1055. 
    4. Krudsood S, Wilairatana P, Mason DP, Treeprasertsuk S, Singhasivanon P, Looareesuwan S. Hidden Plasmodium falciparum infections. Southeast Asian J Trop Med Public Health 1999; 30: 623-624. 
    5. Wilairatana P, Silachamroon U, Krudsood S, Singhasivanon P, Treeprasertsuk S, Bussaratid V, Phumratanaprapin W, Srivilirit S, Looareesuwan S. Efficacy of primaquine-resistant Plamodium vivax in Thailand. Am J Trop Med Hyg 1999; 61: 973-977. 
    6. Mason DP, Krudsood S, Wilairatana P, Viriyavejakul P, Silachamroon U, Chokejindachai W, Singhasivanon P, Supavej S, Mc-Kenzie FE, Looareesuwan S. Can treatment of P. vivax lead to an unexpected appearance of falciparum malaria? Southeast Asian J Trop Med Public Health 2001; 32: 57-63. 
    7. Mayxay M, Pukrittayakamee S, Chotivanich K, Imwong M, Looareesuwan S, White NJ. Identification of cryptic coinfection with Plasmodium falciparum in patients presenting with vivax malaria. Am J Trop Med Hyg 2001; 65: 588-592. 
    8. Maitland K, Williams TN, Bennett S, Newbold CI, Peto TE, Viji J, Timothy R, Clegg JB, Weatherall DJ, Bowden DK. The interaction between Plasmodium falciparum and P. vivax in children on Espiritu Santo Island, Vanuatu. Trans R Soc Trop Med Hyg 1996; 90: 614-620. 
    9. Takagi T, Kano S, Masuda G, Suzuki M. Submicroscopic double infection of Plasmodium falciparum in P. vivax malaria. Trans R Soc Trop Med Hyg 1988; 82: 384. 
    10. Siribal S, Nakasiri S, Looareesuwan S, Chavalitshewinkoon-Petmitr P. Identification of human malaria parasites and detection of mixed infection in Thai patients by nested PCR. Southeast Asian J Trop Med Public Health 2004; 35: 5-9. 
    11. Katakai Y, Chiabchalard R, Komaki-Yasuda K, Kawazu S, Singhasivanon P, Krudsood S, Looareesuwan S, Kano S. Application of real-time polymerase chain reaction (PCR) analysis for detection and discrimination of malaria parasite species in Thai patients. Southeast Asian J Trop Med Public Health 2004; 35: 10-14. 
    12. Baird JK, Schwartz E, Hoffman SL. Prevention and treatment of vivax malaria. Curr Inf Dis Rep 2007; 9: 39-46. 
    13. White NJ. Malaria. In Cook GC, Zumla AI, eds. Manson's Tropical Diseases. 22nd ed. China. Saunders. 2009, p 1274. 
    14. Bryan JP. Cost considerations of malaria chemoprophylaxis including use of primaquine for primary or terminal chemoprophylaxis. Am J Trop Med Hyg 2006; 75: 416-420. 

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