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韓國環境保健學會誌 = Journal of environmental health sciences v.38 no.2, 2012년, pp.105 - 117  
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한국인의 혈 중 PFOA와 PFOS 농도와 노출요인
Concentration of PFOA and PFOS in Whole Blood and Factors Controlling Their Exposure Among Koreans

서춘희   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 이채관   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 이소룡   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 박미희   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 이종태   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 손병철   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 김정호   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  ); 김건형   (인제대학교 의과대학 직업환경의학교실 & 환경.산업의학연구소  );
  • 초록

    Objectives: This study aimed to assess the concentration of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) in blood and factors controlling their exposure among Koreans. Methods: Study subjects were selected to include 718 members of the general population residing in five metropolitan cities and the Gangwon Province area from August 2008 to January 2009. A questionnaire was administered to investigate lifestyle, socio-demographic characteristics, and other related factors. Blood samples were collected and extracted using solid-phase extraction and anion-exchange methods, and quantified by high-performance liquid chromatograph (HPLC, Agilent 1200 Series) coupled with a Triple Quad LC-MS/MS system (Agilent 6410). Results: Geometric mean concentrations of PFOA and PFOS in the blood were measured as 1.82 and 6.06 ng/ml, respectively. Mean PFOA and PFOS concentrations generally increased with age in both genders. Blood PFOA concentration was significantly different according to such variables as age, family income, residential district, and province. Blood PFOS concentration was significantly different by such variables as gender, age, lifestyle factors such as regular exercise, alcohol consumption, and smoking status. Also, family income, hazardous facilities, job classification, and province contributed significantly to differences in blood PFOS concentration levels. Conclusions: Blood PFOA and PFOS concentrations in Koreans were similar with those found in Japan, the USA, and Germany, but less than those in Australia. PFOA and PFOS exposure seems to be affected by a variety of factors in Korea. Therefore, investigation is required for each factor to assess the relative contribution of different variables.


  • 주제어

    perfluorooctanoic acid .   perfluorooctane sulfonate .   blood concentration .   exposure control factors.  

  • 참고문헌 (32)

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