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Korean journal for food science of animal resources = 한국축산식품학회지 v.32 no.2, 2012년, pp.234 - 240   SCIE SCOPUS 피인용횟수: 1
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

돈피 젤라틴 효소분해물이 난소 적출쥐의 골밀도에 미치는 영향
Effect of Pig Skin Gelatin Hydrolysates on the Bone Mineral Density of Ovariectomized Rats

박정은    (농촌진흥청 국립축산과학원   ); 함준상    (농촌진흥청 국립축산과학원   ); 김혜경    (한서대학교 식품생물공학과   ); 이치호    (건국대학교 식품생물공학과   ); 김동욱    (농촌진흥청 국립축산과학원   ); 설국환    (농촌진흥청 국립축산과학원   ); 오미화    (농촌진흥청 국립축산과학원   ); 김동훈    (농촌진흥청 국립축산과학원   ); 장애라    (강원대학교 동물식품응용과학과  );
  • 초록

    본 연구에서는 난소 제거로 인위적으로 골다공증이 유발된 흰쥐를 대상으로 돼지껍질에서 추출한 젤라틴과 저분자 젤라틴 효소분해물 급여가 골밀도에 미치는 영향을 조사하였다. 실험군의 구성은 10주령의 암컷 총 6군으로 난소 적출을 시행 하지 않은 일반 대조군과 난소 적출한 대조군은 일반식이를 급여하였으며, 난소 적출한 실험쥐에 3kDa 이하의 저분자 젤라틴 효소분해물을 0.1, 0.8% 첨가하고, 고분자 젤라틴을 0.1과 0.8% 첨가하여 급여한 후 그 효과를 비교하였다. 체중 증가량은 GH0.1, GH0.8 및 G0.8 급여구에서 NC와 OC에 비해 유의적으로 증가하였으며 특히 GH0.1과 GH0.8처리군은 사료섭취량이 NC와 OC에 비해 증가하였으나 사료효율은 유의적인 차이를 보이지 않았다. 대퇴골의 골밀도는 GH0.8처리군이 OC군에 비해 높았으나(p


    This study was conducted to examine the effects of low molecular weight gelatin hydrolysates (GH, less than 3kDa), extracted from pig skin collagen on the bone metabolism of ovariectomized (OVX) rats. The rats in the experimental groups were randomly segregated into six different treatment groups such as 1) NC, the normal rat fed AIN 93 diet (basal diet) only; 2) OC, the OVX rat fed the basal diet only; 3) GH 0.1, the OVX rat fed the basal diet with 0.1% GH; 4) GH 0.8, the OVX rat fed the basal diet with 0.8% GH; 5) G 0.1, the OVX rat fed the basal diet with 0.1% gelatin; 6) G 0.8, the OVX rat fed the basal diet with 0.8% gelatin. Body weight gain in the GH 0.1, GH 0.8, and G 0.8 was significantly higher than those in the NC and OC. Feed intake of the GH 0.1 and GH 0.8 was higher than that of the NC and OC, while no significant difference was found in feed efficiency ratio (FER). BMD of the GH 0.8 was higher than that of the OC. However, gelatin hydrolysates and gelatin resulted in higher BMC level compare to the OC. Serum HDL-cholesterol of rat fed GH and gelatin was higher than that of OC (p


  • 주제어

    gelatin .   collagen .   osteoporosis .   bone metabolism .   pig skin.  

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  • 이 논문을 인용한 문헌 (1)

    1. Moon, Ji-Young ; Cho, Eun-Ji ; Joo, Seong-Je ; Park, Jong-Hoon ; Yoon, Sung-Ho ; Kim, Man-Do ; Kim, Young-Man ; Hyun, Sook-Kyung ; Lim, Eun Seo ; Kim, Tea Hoon ; Son, Byung-Yil ; Kwon, Hyun-Ju ; Kim, Byung-Woo ; Lee, Eun-Woo 2015. "Effect of Calcium Extracted from Salt-fermented Anchovy Engraulis japonicus on Osteoporosis in Ovariectomized SD-Rats" 한국수산과학회지 = Korean journal of fisheries and aquatic sciences, 48(4): 426~431     

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