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Different isolates of Miamiensis avidus showed differences in virulence to olive flounder (Paralichthys olivaceus) and in sensitivity to chemotherapeutics

Wakabayashi, Chizuha   (Department of Aquatic Life Medicine, Pukyong National University  ); Lim, Hyunju   (Department of Aquatic Life Medicine, Pukyong National University  ); Shin, Min Jun   (Department of Aquatic Life Medicine, Pukyong National University  ); Choi, Myoung Gwang   (Department of Aquatic Life Medicine, Pukyong National University  ); Kim, Min Sun   (Graduate School of Integrated Bioindustry, Sejong University  ); Kim, Ki Hong   (Department of Aquatic Life Medicine, Pukyong National University  );
  • 초록

    Differences in in vivo virulence and in sensitivity to drugs among different isolates of Miamiensis avidus were analyzed. The isolate III showed the highest resistance against the scuticocidal activity of olive flounder (Paralichthys olivaceus) serum, and induced the highest mortalities of olive flounder fingerlings. The isolate II showed significantly higher serum resistance than the isolate I, but in vivo virulence of isolate II was not significantly different from that of isolate I. The secreted proteinases activity of isolate III was significantly higher than that of isolate I and II, and the activity was significantly reduced by the addition of E-64, a cysteine proteinases inhibitor. There were no differences among isolates in the sensitivity to doxycycline, however, there were significant differences in sensitivities to mebendazole and bithionol. These results suggest that the different characteristics of different M. avidus isolates should be taken into consideration for the development of control measures against scuticociliatosis.


  • 주제어

    Miamiensis avidus  . Different isolates  . Virulence  . Drug sensitivity  .

  • 참고문헌 (24)

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