Odontogenic keratocysts—a retrospective clinical and histologic study
Abstract Including 25 recurrences, the material comprised 87 odontogenic keratocysts (OKCs) from 57 patients, who had been treated in 1974–93. The study included an analysis of clinical and histologic data from the patients' records and from pathologic reports. The men:women ratio was 1.5:1. Most of the patients belonged to the age groups 10–19, 20–29, 40–49, and 60–69 years. Almost 75% of the OKCs were localized in the mandible. The most common site was the angle and ascending ramus area. Recurrences comprised 30.5% of the OKCs. The symphysial area of the mandible had the highest recurrence rate (50%). The diagnosis of Gorlin's syndrome was established in two patients. The recurrence rates for the OKCs that were removed in one or in several pieces were 27.5% and 39%, respectively. In 14/87 (16%) cases, microkeratocysts were histologically found. Parakeratosis was observed in 78/87 (89.5%), ortho- and parakeratosis in 6/87 (7%), and orthokeratosis in 3/87 (3.5%) cases. The recurrence rates were 31.5% and 41% for the OKCs that were removed during 1974, 1984, and 1985–90, respectively. In no case could malignant changes be observed at histologic examination.
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