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Long-term outcome of patients who received Starr-Edwards valves between 1965 and 1977

Hayashi, J. (Correspondence to: Dr J. Hayashi. ); Nakazawa, S. (Second Department of Surgery, Niigata University School of Medicine, 1-757 Asahimachidohri, Niigata city, 951, Japan ); Eguchi, S. (Second Department of Surgery, Niigata University School of Medicine, 1-757 Asahimachidohri, Niigata city, 951, Japan ); Ohtani, S. ( ); Asano, K. ( );
  • 초록  

    Abstract To determine the risk factors relating to long-term outcomes of the Starr-Edwards ball valve, data from 150 patients (75 males, 75 females; age range 9–67 years); who underwent valve replacement (44 aortic, 106 mitral) between 1965 and 1977 at Niigata University were reviewed retrospectively. Valve models 6120/6320 and 1260/2320 were mainly used in mitral and aortic positions, respectively. The cumulative follow-up period was 2227.4 patient-years. Using the Kaplan-Meier life-table method, actuarial probability of freedom from valve-related mortality, morbidity and thromboembotism were analysed. Thirteen patients died from various causes during hospitalization. Some 80 patients suffered 97 instances of valve-related morbidity and 58 died during follow-up (up to 28 years). Patient age >50 years affected the actuarial probability of freedom from valve-related mortality in the entire group ( P < 0.05). Valve type and the year of operation were discriminative predictors of thromboembolic complications in the entire group (both P < 0.05) and in the mitral valve replacement group ( P < 0.01 and P < 0.001). However, only the year of operation affected the actuarial probability of freedom from all valve-related morbidity in the entire group and in the mitral valve replacement group (both P <0.05). Univariate analysis revealed that age at surgery, valve type, and the year of operation were related to late postoperative outcome in patients who received a Starr-Edwards ball valve between 1965 and 1977.


  • 주제어

    Starr-Edwards valve .   risk factor .   thromboembolism .   valve-related mortality .   valve-related morbidity.  

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