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Gallbladder Motility Change in Late Pregnancy and after Delivery

Hahm, Joon Soo    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Park, Joon Yong    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Song, Seung Chan    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Cho, Yun Ju    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Moon, Kwang Ho    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Song, Yong Ho    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Lee, Oh Young    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Choi, Ho Soon    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Yoon, Byung Chul    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Lee, Min Ho    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Kee, Choon Suhk    (Department of Internal Medicine, College of Medicine, Hanyang University, Seoul, Korea   ); Park, Kyung Nam    (Department of Interna  );
  • 초록

    Objectives The incidence of gallstone disease has increased recently in Korea and there seems to be an increased prevalence of gallstones when in association with pregnancy. Although the pathogenesis is incompletely defined, an altered motility of the gallbladder may contribute to the increased risk of gallstones during pregnancy. Methods We measured gallbladder volume using real-time ultrasonography to find out the mechanism for the changes of gallbladder motility during late pregnancy. Eighteen pregnant women took the gallbladder ultrasonography during their last trimester of pregnancy and after delivery: gallbladder volume and ejection fraction were calculated in each patient. Results Fasting gallbladder volumes increased significantly in the last trimester of pregnancy (25.28± 14.26ml) compared with postpartum (17.44±5.82ml) ( p p p Conclusion Gallbladder motility in late pregnancy shows significant impairment compared with that in postpartum. Thus, we suggest that gallbladder hypomotility may occur during late pregnancy, and this impairment of gallbladder motility may play an important role in gallstone formation.


  • 주제어

    Gallstone .   Pregnancy .   Gallbladder motility.  

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