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A Case of Gastric Cancer Initially Presenting with Polydipsia

Han, Seungsuk    (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Kim, Hae Sung    (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Jang, Hak C.    (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Whang, Il Soon    (Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Kim, Hy Sook    (Department of Anatomical Pathology, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Kim, Hye Sun    (Department of Anatomical Pathology, Sungkyunkwan University School of Medicine, Seoul, Korea   ); Lee, Kyung Sang    (Department of Diagnostic Radiology Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea  );
  • 초록

    Metastatic brain tumors from gastric cancer are extremely rare. A 61-year-old Korean woman, initially presenting with polydipsia and polyuria, was found to have metastatic lesions in the brain by MRI. We performed several diagnostic procedures to determine the origin of the brain metastases. She was revealed to have a soft tissue mass of the right adrenal gland and fungating ulcers in the stomach. Histologic studies of both the adrenal gland mass and gastric tissues revealed malignant tumors composed of anaplastic cells. Based on the electron microscopy study, the malignant tumor of the right adrenal gland was a metastatic lesion from the anaplastic carcinoma of stomach. Therefore, the malignant tumors of the brain were assumed to have originated from the gastric cancer. This case report is presented to make clinicians aware of the possibility that diabetes insipidus (polydipsia) may present as an initial manifestation of brain metastases.


  • 주제어

    Brain metastasis .   Diabetes insipidus .   Gastric cancer.  

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