Characterization and in vivo evaluation of calcium phosphate coated cp-titanium by dip-spin method
Calcium phosphate ceramics like hydroxyapatite (HA) and tricalcium phosphate (TCP) are good candidates for bone substitutes due to their chemical similarity to bone minerals. Additionally, the biodegradation property of bone substitutes may allow the organism to replace the foreign material by fully functional new bone in a balanced time schedule. Thus, the coating of biodegradable calcium phosphate ceramics on dental implants was conducted in this study to enhance the biocompatibility and eliminate the long-term adverse effects of HA coated implants. First, biodegradable calcium metaphosphate(CMP) sol was prepared and then coated on cp-Ti substrates by a dip-spin coating technique. The coated specimens were heat-treated at 600 o C for 6h. CMP coated layer on cp-Ti was smooth and uniform with fine grains. It is observed that bone-to-implant contact area of CMP coated specimen at both 2 and 6 weeks was significantly higher than that of non-coated group. The biocompatibility and cytotoxicity of the CMP coated specimen were better than those of the non-coated specimen. Therefore, the CMP coating on cp-Ti is a good candidate for improving bone-to-implant osseointegration, although it is difficult to extrapolate in vitro results directly to in vivo situation.
유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.
원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.
NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.
- 이 논문과 함께 출판된 논문 + 더보기