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Journal of Korean medical science : JKMS v.21 no.6 = no.112, 2006년, pp.1012 - 1016  
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Comparison of Allergic Indices in Monosensitized and Polysensitized Patients with Childhood Asthma

Kim, Kyung Won    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Kim, Eun Ah    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Kwon, Byoung Chul    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Kim, Eun Soo    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Song, Tae Won    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Sohn, Myung Hyun    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, Seoul, Korea.   ); Kim, Kyu-Earn    (Department of Pediatrics and Institute of Allergy, Biomolecule Secretion Research Center, Yonsei University College of Medicine, S  );
  • 초록

    Monosensitization differs both immunologically and clinically from polysensitization, and specific immunotherapy is more effective in patients sensitized only to a single pollen than in multiple-pollen sensitized patients. To further examine the differences between monosensitized and polysensitized allergies, allergic indices were examined in 68 monosensitized and 62 polysensitized patients with childhood asthma. Measurements included symptom scores, eosinophil counts, skin prick tests, serum total and specific IgE levels, and IL-10 levels, and were used to compare allergic indices between the two groups. Patients were followed for 18 months following immunotherapy to examine the effectiveness of the treatment. Symptom scores and total IgE levels were significantly higher in the polysensitized group than those in the monosensitized group ( p p p p


  • 주제어

    Asthma .   Child .   Immunotherapy .   Immunoglobulin E.  

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