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Journal of Korean medical science : JKMS v.21 no.6 = no.112, 2006년, pp.1041 - 1047  
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Analysis of Endoscopic Electronic Image of Intramucosal Gastric Carcinoma Using a Software Program for Calculating Hemoglobin Index

Kim, Gwang Ha    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Kim, Kwang Baek    (Department of Computer Engineering, Silla University, Busan, Korea.   ); Lim, Eun Kyung    (School of Computer Engineering, Pusan National University, Busan, Korea.   ); Choi, Seong Ho    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Kim, Tae Oh    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Heo, Jeong    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Kang, Dae Hwan    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Song, Geun Am    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Research Institute, Busan, Korea.   ); Cho, Mong    (Department of Internal Medicine, Pusan National University College of Medicine and Medical Re  ); Park, Do Youn  
  • 초록

    Hemoglobin is the predominent pigment in the gastrointestinal mucosa, and the development of electronic endoscopy has made it possible to quantitatively measure the mucosal hemoglobin volume, by using a hemoglobin index (IHb). The aims of this study were to make a software program to calculate the IHb and then to investigate whether the mucosal IHb determined from the electronic endoscopic data is a useful marker for evaluating the color of intramucosal gastric carcinoma with regard to its value for discriminating between the histologic types. We made a software program for calculating the IHb in the endoscopic images. By using this program, the mean values of the IHb for the carcinoma (IHb-C) and those of the IHb for the surrounding non-cancerous mucosa (IHb-N) were calculated in 75 intestinal-type and 34 diffuse-type intramucosal gastric carcinomas. We then analyzed the ratio of the IHb-C to the IHb-N (C/N ratio). The C/N ratio in the intestinal-type carcinoma group was higher than that in the diffuse-type carcinoma group ( p p = 0.022). The accuracy rate, sensitivity, specificity, and the positive and negative predictive values for the differential diagnosis of the diffuse-type carcinoma from the intestinal-type carcinoma were 94.5%, 94.1%, 94.7%, 88.9% and 97.3%, respectively. IHb is useful for making quantitative measurement of the endoscopic color in the intramucosal gastric carcinoma, and the C/N ratio by using the IHb would be helpful for distinguishing the diffuse-type carcinoma from the intestinal-type carcinoma.


  • 주제어

    Stomach Neoplasms .   Hemoglobin Index .   Software .   Software Validation .   Endoscopy .   Image, Endoscopy.  

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