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Journal of veterinary science v.8 no.3, 2007년, pp.223 - 227  

Effectiveness of 99m Tc-tetrofosmin for assessment of heart functions in micropigs

Lee, Min Young    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Lee, Sang Hun    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Park, Jae Hong    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Heo, Jung Sun    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Lee, Yu Jin    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Suh, Han Na    (College of Veterinary Medicine, Biotherapy Human Resources Center, Chonnam National University, Gwangju 500-757, Korea.   ); Min, Jung Jun    (Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun 519-809, Korea.   ); Seo, Young Soon    (Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun 519-809, Korea.   ); Han, Ho Jae    (College of Veterinary Medicine, Biotherapy Human Resources Cente  );
  • 초록

    This study examined the suitability of a nuclear imaging technique using 99m Tc-tetrofosmin as an agent to assess the heart functions of healthy micropigs. The mean age of the pigs was 360 days (male), and the mean body weight was 35.3 kg ranging from 34.5-36 kg. There were no significant perfusion defects in any of the reconstructed images. Gated single-photon emission computed tomography imaging can be used to calculate the ventricular volume and ejection fraction (EF). In this case, an EF of 79% was calculated from the ventricular volume of the end-systolic image (10 ml) subtracted from that of the end-diastolic volume (49 ml). A perfusion defect (particularly the apex, lateral wall) is unlikely because of the presence of a preserved wall motion in a segment with a defect. It is concluded that quantitative cardiac scintigraphy, using 99m Tc-tetrofosmin is an adequate technique for estimating the heart functions of healthy micropigs.


  • 주제어

    ejection fraction (EF) .   heart function .   micropig .   99mTc-tetrofosmin.  

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