본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Chemical research in toxicology v.30 no.1, 2017년, pp.239 - 259   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

New Approaches to Investigate Drug-Induced Hypersensitivity

Ogese, Monday O. (Pathology Sciences, Drug Safety and Metabolism, AstraZeneca R&D, Darwin Building 310, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, ); Ahmed, Shaheda ( Alcyomics Ltd c/o Haematological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, ); Alferivic, Ana ( MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Ashton Street, Liverpool L69 3GE, ); Betts, Catherine J. ( Pathology Sciences, Drug Safety and Metabolism, AstraZeneca R&D, Darwin Building 310, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, ); Dickinson, Anne ( Alcyomics Ltd c/o Haematological Sciences, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, ); Faulkner, Lee ( MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Ashton Street, Liverpool L69 3GE, ); French, Neil ( MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Ashton Street, Liverpool L69 3GE, ); Gibson, Andrew ( MRC Centre f ); Hirschfield, Gideon M. ( ); Kammü ( ); ller, Michael ( ); Meng, Xiaoli ( ); Martin, Stefan F. ( ); Musette, Philippe ( ); Norris, Alan ( ); Pirmohamed, Munir ( ); Park, B. Kevin ( ); Purcell, Anthony W. ( ); Spraggs, Colin F. ( ); Whritenour, Jessica ( ); Naisbitt, Dean J. ( );
  • 초록  

    The workshop on “New Approaches to Investigate Drug-Induced Hypersensitivity” was held on June 5, 2014 at the Foresight Center, University of Liverpool. The aims of the workshop were to (1) discuss our current understanding of the genetic, clinical, and chemical basis of small molecule drug hypersensitivity, (2) highlight the current status of assays that might be developed to predict potential drug immunogenicity, and (3) identify the limitations, knowledge gaps, and challenges that limit the use of these assays and utilize the knowledge gained from the workshop to develop a pathway to establish new and improved assays that better predict drug-induced hypersensitivity reactions during the early stages of drug development. This perspective reviews the clinical and immunological bases of drug hypersensitivity and summarizes various experts’ views on the different topics covered during the meeting. Graphic Abstract


 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기