Efficacy of a Rhealba? Oat Extract‐based emollient on chronic pruritus in elderly French outpatients
Abstract Background Chronic pruritus, defined as itch persisting more than 6?weeks, is a debilitating problem that affects one in four elderly adults. Emollients are recommended for the management of pruritus, but evidence of efficacy is scarce. Objective Assess the efficacy of a Rhealba ? Oat Extract‐based emollient in the management of chronic pruritus in elderly outpatients. Methods This was a randomized, mono‐centric, open‐label, cross‐over study in adults ≥60?years of age with xerosis associated with chronic pruritus. Subjects were randomized 1:1 to start with a 2‐week non‐treatment phase or a 2‐week treatment phase in which they applied the emollient once or twice daily. The primary outcome was subject‐assessed pruritus using an established visual analogue scale. Subjects also assessed pruritus using the 5‐D itch scale. Investigators assessed xerosis using the Overall Dry Skin Score and measured hydration index by Corneometer ? , desquamation by D‐Squame and transepidermal water loss by Aquaflux ? . Results Thirty subjects were included. Pruritus intensity on the visual analogue scale improved significantly more during the treatment phase than during the non‐treatment phase ( P ? P ? P ?=?0.0042). At the end of the treatment phase, more than half of the subjects reported an improvement in pruritus, and 30% reported complete disappearance, whereas pruritus remained stable during the non‐treatment phase ( P? P ? Conclusion Daily use of a Rhealba Oat Extract‐based emollient can provide relief to elderly adults who suffer from xerosis associated with chronic pruritus.
- 원문이 없습니다.
유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.
원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.
NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.
- 이 논문과 함께 출판된 논문 + 더보기