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Journal of clinical nursing v.26 no.3/4, 2017년, pp.411 - 417   SCIE SSCI
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Clinical factors and incidence of prolonged fever in neurosurgical patients

Wang, Zhuo (School of Nursing, Medical College of Huzhou University, Huzhou, China ) ; Shen, Meifen (School of Nursing, Medical College of Soochow University, Suzhou, China ) ; Qiao, Meizhen (Department of Infection Control, the First Affiliated Hospital of Soochow University, Suzhou, China ) ; Zhang, Haiyin (Department of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou, China ) ; Tang, Zaixiang (Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China ) ;
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    Aims and objectives To describe the incidence of prolonged fever in patients admitted to the neurosurgery department, and the corresponding risk indicators. Background Prolonged fever was defined as a temperature higher than 38·3°C lasting more than five days. Prolonged fever is a common phenomenon and could lead to worsened outcomes in specific patient groups, especially for those with brain injury. However, the studies on prolonged fever in neurosurgical patients are limited and insufficient. Design A retrospective observational study. Methods Retrospective data were collected from 1 January 2014 to 31 December 2014, at the neurosurgical department of a large teaching hospital. We performed univariate and multivariate analyses to identify independent indicators for prolonged fever vs. short‐term fever. Results Among 2845 patients, prolonged fever occurred in 466 (16%). The older patients were associated with longer duration of mechanical ventilation and hospital stay. It predominantly occurred in patients with subarachnoid haemorrhage (SAH) and traumatic brain injury. Patients receiving antibiotic treatment tended to manifest prolonged fever more frequently. Multivariate analysis revealed that the use of antibiotics, central venous catheter and prolonged mechanical ventilation were independent risk predictors for prolonged fever. Patients diagnosed with brain tumour seemed to be not associated with prolonged fever. Conclusions Prolonged fever is the common complication in neurosurgical patients. The risks of prolonged fever in patients are attributed to antibiotic therapy, use of central venous catheter and prolonged mechanical ventilation. Indicators of prolonged fever are helpful for better identification of high‐risk patients and fever control. Relevance to clinical practice A better reveal on the epidemiology and predictable factors of prolonged fever in neurosurgical patients will provide a better understanding on those patients who are most at risk, and therefore contribute to fever control and better outcome.


  • 주제어

    antibiotic therapy .   central venous catheter .   neurosurgical patients .   prolonged fever .   prolonged mechanical ventilation.  

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