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Journal of viral hepatitis v.24 no.3, 2017년, pp.207 - 215   SCI SCIE
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Multidisciplinary managed care networks—Life‐saving interventions for hepatitis C patients

Tait, J. M. (University of Dundee, Dundee, UK ); Wang, H. ( Department of Gastroenterology, Ninewells Hospital and Medical School, Dundee, UK ); Stephens, B. P. ( Department of Gastroenterology, Ninewells Hospital and Medical School, Dundee, UK ); Miller, M. ( Department of Gastroenterology, Ninewells Hospital and Medical School, Dundee, UK ); McIntyre, P. G. ( University of Dundee, Dundee, UK ); Cleary, S. ( Department of Gastroenterology, Ninewells Hospital and Medical School, Dundee, UK ); Dillon, J. F. ( );
  • 초록  

    Summary Successful hepatitis C virus (HCV) therapy depends on effective pathways of care. Over two decades, we have developed four sequential models of care latterly using a multidisciplinary managed care network to improve HCV testing, care and treatment. This was a cohort study to evaluate the effectiveness of care pathways, carried out using all HCV antibody‐positive individuals tested in a geographical region between 1994 and 2014. The study involved 3122 HCV‐positive patients. They were divided into four subgroups representing different care pathways defined by their date of HCV antibody diagnosis. The number who accessed treatment services within 1 year of diagnosis increased from 77 of 292 (26.3%) to 521 of 821 (72.9%). The rate of treatment starts within 1 year of diagnosis increased from 6 of 292 (2.0%) to 133 of 821 (16.2%), and the sustained viral response rate improved from 61.6% to 77.4%. All‐cause mortality decreased from 232 of 688 (33.7%) in subgroup A to 55 of 1207 (4.5%) in subgroup D, and multivariate analysis showed that pathway type was an independent predictor of mortality irrespective of age, sex, SVR status or HIV co‐infection with pathway in D having an odds ratio of 0.53(0.40‐0.77; P


  • 주제어

    access to care .   hepatitis C virus .   managed care networks .   people who inject drugs .   sustained viral response.  

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