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The American journal of medicine v.130 no.2, 2017년, pp.188 - 197.e5   SCI SCIE
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Associations of Coffee, Tea, and Caffeine Intake with Coronary Artery Calcification and Cardiovascular Events

Miller, P. Elliott (Department of Critical Care Medicine, National Institutes of Health, Bethesda, Md ) ; Zhao, Di (Department of Epidemiology, Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md ) ; Frazier-Wood, Alexis C. (Children's Nutrition Research Center, Baylor College of Medicine, Houston, Tex ) ; Michos, Erin D. (Division of Cardiology, Department of Medicine, Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University School of Medicine, Baltimore, Md ) ; Averill, Michelle (Department of Environmental and Occupational Health, University of Washington, Seattle ) ; Sandfort, Veit (Department of Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Md ) ; Burke, Gregory L. (Division of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC ) ; Polak, Joseph F. (Department of Radiology, Tufts Medical Center, Tufts University School of Medicine, Boston, Mass ) ; Lima, Joao A.C. (Division of Cardiology, Department of Medicine, Johns Hopkins Hospital, Baltimore, Md ) ; Post, Wendy S. (Division of Ca ) ; Blumenthal, Roger S. ; Guallar, Eliseo ; Martin, Seth S. ;
  • 초록  

    Abstract Background Coffee and tea are 2 of the most commonly consumed beverages in the world. The association of coffee and tea intake with coronary artery calcium and major adverse cardiovascular events remains uncertain. Methods We examined 6508 ethnically diverse participants with available coffee and tea data from the Multi-Ethnic Study of Atherosclerosis. Intake for each was classified as never, occasional ( Results Over a median follow-up of 5.3 years for coronary artery calcium and 11.1 years for cardiovascular events, participants who regularly drank tea (≥1 cup per day) had a slower progression of coronary artery calcium compared with never drinkers after multivariable adjustment. This correlated with a statistically significant lower incidence of cardiovascular events for ≥1 cup per day tea drinkers (adjusted hazard ratio 0.71; 95% confidence interval 0.53-0.95). Compared with never coffee drinkers, regular coffee intake (≥1 cup per day) was not statistically associated with coronary artery calcium progression or cardiovascular events (adjusted hazard ratio 0.97; 95% confidence interval 0.78-1.20). Caffeine intake was marginally inversely associated with coronary artery calcium progression. Conclusions Moderate tea drinkers had slower progression of coronary artery calcium and reduced risk for cardiovascular events. Future research is needed to understand the potentially protective nature of moderate tea intake.


  • 주제어

    Caffeine .   Cardiovascular events .   Coffee .   Coronary artery calcium .   Tea.  

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