본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Chemosphere v.172, 2017년, pp.29 - 36   SCI SCIE SCOPUS
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Maternal urinary paraben levels and offspring size at birth from a Chinese birth cohort

Wu, Chuansha (Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ); Huo, Wenqian ( Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ); Li, Yuanyuan ( Key Laboratory of Environment and Health, Ministry of Education & Ministry of Environmental Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China ); Zhang, Bin ( Women and Children Medical and Healthcare Center of Wuhan, Wuhan, Hubei, China ); Wan, Yanjian ( CDC of Yangtze River Administration and Navigational Affairs, General Hospital of the Yangtze River Shi ); Zheng, Tongzhang ( ); Zhou, Aifen ( ); Chen, Zhong ( ); Qian, Minzheng ( ); Zhu, Yingshuang ( ); Jiang, Yangqian ( ); Liu, Hongxiu ( ); Hu, Jie ( ); Chen, Xi ( ); Xu, Bing ( ); Xia, Wei ( ); Xu, Shunqing ( );
  • 초록  

    Abstract Background Parabens are suspected to impair fetal growth because of their endocrine disrupting effects. Epidemiological studies regarding the effects of prenatal exposure to parabens on birth outcomes are limited. Objectives Our aim was to evaluate the association between prenatal paraben exposure and size of infants at birth. Methods Within the longitudinal Healthy Baby Cohort (HBC) in Hubei Province, China, we randomly selected 1006 mother-infant pairs recruited in Wuhan City in 2014. Concentrations of parabens were measured in maternal urine collected before delivery. General linear models were used to analyze the associations of maternal parabens exposure levels with birth weight and birth length. Results The specific gravity adjusted geometric means for urinary concentrations of methyl paraben (MeP), ethyl paraben (EtP), and propyl paraben (PrP) were 5.41, 0.11, and 0.94?ng/mL, respectively. Maternal urinary concentrations of parabens tended to be positively associated with birth weight in boys, while opposite trends were found in girls, though these associations were not significant. Higher maternal urinary levels of MeP were positively associated with birth length in boys (β?=?0.30, 95% CI: 0.01, 0.58 for the medium tertile, and β?=?0.30, 95% CI: 0.01, 0.58 for the highest tertile compared to the lowest tertile); however, no significant associations with birth length were observed in girls. Conclusions Maternal urinary levels of MeP were positively associated with length at birth in boys. Besides, we did not find strong associations of the current exposure levels of parabens in Chinese pregnant women with size of infants at birth. Highlights This is the first study to assess paraben exposure in Chinese pregnant women. Parabens were detected in the majority of urine samples in Chinese pregnant women. The association of maternal urinary parabens with infants' birth size was examined. Maternal urinary levels of MeP were positively associated with birth length in boys.


  • 주제어

    Parabens .   Birth size .   Maternal urine .   Birth cohort.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기