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IEEE transactions on bio-medical engineering v.64 no.2, 2017년, pp.310 - 318   SCI SCIE
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Identification of Rotors during Human Atrial Fibrillation Using Contact Mapping and Phase Singularity Detection: Technical Considerations

Kuklik, Pawel (Department of PhysiologyMaastricht University ); Zeemering, Stef ( Department of PhysiologyMaastricht University ); van Hunnik, Arne ( Department of Cardio-thoracic SurgeryMaastricht University Medical Centre ); Maesen, Bart ( Department of CardiologyMaastricht University Medical Centre ); Pison, Laurent ( Centre for Heart Rhythm Disorders, South Australian Health and Medical Research InstituteUniversity of Adelaide and Royal Adelaide Hospital ); Lau, Dennis H ( Department of Cardio-thoracic SurgeryMaastricht University Medical Centre ); Maessen, Jos ( Faculty of PhysicsWarsaw University of Technology ); Podziemski, Piotr ( Department of Cardiology and Electrophysiology, University Heart CenterUniversity Hospital Hamburg-Eppendorf ); Meyer, Christian ( Department of Cardiology and Electrophysiology, University Heart CenterUniversity Hospital Hamburg-Eppendorf ); Schaffer, Benjamin ( Department of CardiologyMaastricht University Medical Centre ); Crijns, Harry ( Department of Cardiology and Electrophysiology, University Heart CenterUniversity Hospital Hamburg-Eppendorf ); Willems, Stephan ( Department of PhysiologyMaastricht University ); Schotten, Ulrich ( );
  • 초록  

    Objective: To explore technical challenges of phase singularity (PS) mapping during atrial fibrillation (AF) using direct contact electrograms. Methods: AF mapping was performed in high-density epicardial recordings of human paroxysmal (PAF) or persistent (PersAF) ( N = 20 pts) AF with an array of 16 × 16 electrodes placed on atrial epicardium. PS points were detected using subsets of electrodes forming rings of varying sizes. Results: PS detection using a 2 × 2 electrode ring identified 0.88 ± 1.00 PS/s in PAF group and 3.91 ± 2.51 per s in PersAF group ( p


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