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Journal of clinical periodontology v.44 no.2, 2017년, pp.158 - 168   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Long‐term clinical response to treatment and maintenance of localized aggressive periodontitis: a cohort study

Miller, Karina A. F. S. (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Branco‐de‐Almeida, Luciana S. (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Wolf, Sandra (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Hovencamp, Nicole (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Treloar, Tina (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Harrison, Peter (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Aukhil, Ikramuddin (Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA ) ; Gong, Yan (Department of Pharmacotherapy and Transla ) ; Shaddox, Luciana M. ;
  • 초록  

    Abstract Aim To evaluate long‐term clinical response to periodontal therapy and maintenance in localized aggressive periodontitis (LAP). Materials and Methods One hundred forty‐one African Americans diagnosed with LAP, aged 5–25 years, were enrolled. Patients underwent periodontal mechanical debridement plus 1 week of amoxicillin/metronidazole. Mechanical therapy was repeated as needed and clinical parameters were recorded at baseline, 3, 6, 12, 18 and 24 months, and two additional annual follow‐up visits after treatment. Radiographs from primary dentition of patients with LAP in permanent dentition, and additional healthy siblings (HS) were analysed retrospectively. Results Periodontal therapy significantly improved probing depth and clinical attachment level up to 4 years (mean reductions: 2.18 ± 1.03 and 2.80 ± 1.43 mm, respectively). Percentage of affected sites was reduced at all time points and maintained up to 4 years. Non‐compliance with antibiotics/appointments negatively affected the treatment response. Ninety per cent of LAP patients in permanent dentition and 32% of HS presented radiographic bone loss in primary dentition. Conclusions Mechanical debridement with 1 week of systemic antibiotics along with proper periodontal maintenance was effective in the treatment and successful maintenance of LAP for up to 4 years. LAP in permanent dentition may be preceded in the primary dentition. Clinicaltrials.gov #NCT01330719.


  • 주제어

    aggressive periodontitis .   antibiotics .   dental scaling .   long‐term effects .   maintenance .   patient compliance .   root planing .   therapy.  

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