본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Gut: journal of the British Society of Gastroenterology v.66 no.3, 2017년, pp.438 - 445   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Adenoma detection with Endocuff colonoscopy versus conventional colonoscopy: a multicentre randomised controlled trial

van Doorn, SC (Departments of Gastroenterology & Hepatology, Academic Medical Centre, University of Amsterdam, , Amsterdam, The Netherlands ) ; van der Vlugt, M (Departments of Gastroenterology & Hepatology, Academic Medical Centre, University of Amsterdam, , Amsterdam, The Netherlands ) ; Depla, ACTM (Departments of Gastroenterology & Hepatology, Slotervaartziekenhuis, , Amsterdam, The Netherlands ) ; Wientjes, CA (Departments of Gastroenterology & Hepatology, Sint Lucas Andreas Ziekenhuis, , Amsterdam, The Netherlands ) ; Mallant-Hent, RC (Departments of Gastroenterology & Hepatology, Flevoziekenhuis, , Almere, The Netherlands ) ; Siersema, PD (Departments of Gastroenterology & Hepatology, University Medical Centre Utrecht, , Utrecht, The Netherlands ) ; Tytgat, KMAJ (Departments of Gastroenterology & Hepatology, Academic Medical Centre, University of Amsterdam, , Amsterdam, The Netherlands ) ; Tuynman, H (Departments of Gastroenterology & Hepatology, Sint Lucas Andreas Ziekenhuis, , Amsterdam, The Netherlands ) ; Kuiken, SD (Departments of Gastroenterology & Hepatology, Slotervaartziekenhuis, , Amsterdam, The Netherlands ) ; Houben, GMP (De ) ; Stokkers, PCF ; Moons, LMG ; Bossuyt, PMM ; Fockens, P ; Mundt, MW ; Dekker, E ;
  • 초록  

    Background and aims Colonoscopy is the current reference standard for the detection of colorectal neoplasia, but nevertheless adenomas remain undetected. The Endocuff, an endoscopic cap with plastic projections, may improve colonic visualisation and adenoma detection. The aim of this study was to compare the mean number of adenomas per patient (MAP) and the adenoma detection rate (ADR) between Endocuff-assisted colonoscopy (EAC) and conventional colonoscopy (CC). Methods We performed a multicentre, randomised controlled trial in five hospitals and included fecal immonochemical test (FIT)-positive screening participants as well as symptomatic patients (>45 years). Consenting patients were randomised 1:1 to EAC or CC. All colonoscopies were performed by experienced colonoscopists (≥500 colonoscopies) who were trained in EAC. All colonoscopy quality indicators were prospectively recorded. Findings Of the 1063 included patients (52% male, median age 65 years), 530 were allocated to EAC and 533 to CC. More adenomas were detected with EAC, 722 vs 621, but the gain in MAP was not significant: on average 1.36 per patient in the EAC group versus 1.17 in the CC group (p=0.08). In a per-protocol analysis, the gain was 1.44 vs 1.19 (p=0.02), respectively. In the EAC group, 275 patients (52%) had one or more adenomas detected versus 278 in the CC group (52%; p=0.92). For advanced adenomas these numbers were 109 (21%) vs 117 (22%). The adjusted caecal intubation rate was lower with EAC (94% vs 99%; p<0.001), however when allowing crossover from EAC to CC, they were similar in both groups (98% vs 99%; p value=0.25). Interpretation Though more adenomas are detected with EAC, the routine use of Endocuff does not translate in a higher number of patients with one or more adenomas detected. Whether increased detection ultimately results in a lower rate of interval carcinomas is not yet known. Trial registration number http://www.trialregister.nl Dutch Trial Register: NTR3962.


  • 주제어

    COLORECTAL CANCER .   POLYP .   COLONOSCOPY .   COLORECTAL ADENOMAS.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기