본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Spinal cord : the official journal of the International Medical Society of Paraplegia v.54 no.12, 2016년, pp.1215 - 1219   SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Spinal cord injury and Parkinson's disease: a population-based, propensity score-matched, longitudinal follow-up study

Yeh, T-S (Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Yun-Lin Branch, Yunlin, Taiwan ) ; Huang, Y-P (Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Yun-Lin Branch, Yunlin, Taiwan ) ; Wang, H-I (Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan ) ; Pan, S-L (Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan ) ;
  • 초록  

    Objectives:To investigate whether patients with spinal cord injury (SCI) are at an increased risk of developing Parkinson’s disease (PD).Study design:A population-based, propensity score-matched, longitudinal follow-up cohort study.Setting:The study was conducted using the National Health Insurance (NHI) Research Database.Methods:A total of 10 125 patients with at least 2 ambulatory visits with a diagnosis of SCI in 2001 were enrolled in the SCI group. The non-SCI group comprised 10 125 propensity score-matched patients without SCI. The propensity scores were computed using a logistic regression model that included age, sex, comorbidities and socioeconomic status. The PD-free survival rates of the two groups were estimated using the Kaplan–Meier method. Stratified Cox proportional hazard regression was used to estimate the effect of SCI on subsequent occurrence of PD.Results:During the 3-year follow-up period, 99 subjects in the SCI group and 59 in the non-SCI group developed PD. The hazard ratio of PD for the SCI group compared with the non-SCI group was 1.65 (95% confidence interval 1.16–2.33, P=0.0049). The PD-free survival rate for the SCI group was lower than that for the non-SCI group (P=0.0017).Conclusions:This study shows that SCI is associated with a subsequent increased risk of PD. Further studies are needed to elucidate the mechanism underlying this association.


 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기