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Gynecologic oncology v.147 no.3, 2017년, pp.597 - 600   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Hormone replacement therapy after treatment for cervical cancer: Are we adhering to standard of care?

Rauh, Lisa A.    (Department of Obstetrics and Gynecologic, Division of Gynecologic Oncology, University of Virginia, Charlottesville, VA, United States   ); Pannone, Aaron F.    (Department of Public Health Sciences, University of Virginia, Charlottesville, VA, United States   ); Cantrell, Leigh A.    (Department of Obstetrics and Gynecologic, Division of Gynecologic Oncology, University of Virginia, Charlottesville, VA, United States  );
  • 초록  

    Abstract Objective The aim of this study was to assess hormone replacement therapy (HRT) and bone care health maintenance practices for cervical cancer patients with iatrogenic menopause, and, secondarily, to investigate the potential impact of specific demographic and clinical factors. Methods Women diagnosed with iatrogenic menopause due to cervical cancer treatment between January 1, 2005 and December 31, 2015 were identified from the University of Virginia's tumor registry. Univariable data were analyzed using Wilcoxon rank sum, Chi square, and Fisher's exact test; multivariable analysis was conducted using logistic regression. Results Two hundred and two women were included for analysis. Ninety-seven of these women (48.0%) received counseling and/or a prescription for HRT. After multivariable analysis, older age at diagnosis (adjusted OR 0.940, 95% CI 0.890–0.993, p = 0.0270) and uninsured payer status (adjusted OR 0.455, 95% CI 0.212–0.977, p = 0.0435) were associated with a decreased likelihood of receiving counseling or a prescription for HRT. A longer duration of follow-up was associated with the primary outcome with an adjusted OR of 1.011 (95% CI 1.001–1.020, p = value 0.0252). Dual-energy X-ray absorptiometry scans (DEXA) were infrequent and received by only 17/197 (8.6%) of all women. Conclusions Fewer than half of all women received counseling and/or a prescription for HRT after diagnoses of iatrogenic menopause, and disparities were noted based on insurance status. These findings reflect a need for clearer guidelines on HRT during survivorship and improved efforts to reduce disparities in the distribution of survivorship care. Highlights 48% of patients received counseling for hormone replacement therapy (HRT). Older and uninsured patients were significantly less likely to receive HRT. Bone health maintenance practices were infrequently discussed or prescribed.


  • 주제어

    Cervix .   Cancer .   Hormone .   Replacement.  

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