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NeuroImage v.162, 2017년, pp.13 - 22   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

3D MR fingerprinting with accelerated stack-of-spirals and hybrid sliding-window and GRAPPA reconstruction

Liao, Congyu    (Center for Brain Imaging Science and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, Zhejiang, China   ); Bilgic, Berkin    (Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA   ); Manhard, Mary Kate    (Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA   ); Zhao, Bo    (Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA   ); Cao, Xiaozhi    (Center for Brain Imaging Science and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, Zhejiang, China   ); Zhong, Jianhui    (Center for Brain Imaging Science and Technology, Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, Zhejiang, China  ); Wald, Lawrence L.   Setsompop, Kawin  
  • 초록  

    Abstract Purpose Whole-brain high-resolution quantitative imaging is extremely encoding intensive, and its rapid and robust acquisition remains a challenge. Here we present a 3D MR fingerprinting (MRF) acquisition with a hybrid sliding-window (SW) and GRAPPA reconstruction strategy to obtain high-resolution T 1 , T 2 and proton density (PD) maps with whole brain coverage in a clinically feasible timeframe. Methods 3D MRF data were acquired using a highly under-sampled stack-of-spirals trajectory with a steady-state precession (FISP) sequence. For data reconstruction, k x -k y under-sampling was mitigated using SW combination along the temporal axis. Non-uniform fast Fourier transform (NUFFT) was then applied to create Cartesian k-space data that are fully-sampled in the in-plane direction, and Cartesian GRAPPA was performed to resolve k z under-sampling to create an alias-free SW dataset. T 1 , T 2 and PD maps were then obtained using dictionary matching. Results Phantom study demonstrated that the proposed 3D-MRF acquisition/reconstruction method is able to produce quantitative maps that are consistent with conventional quantification techniques. Retrospectively under-sampled in vivo acquisition revealed that SW + GRAPPA substantially improves quantification accuracy over the current state-of-the-art accelerated 3D MRF. Prospectively under-sampled in vivo study showed that whole brain T 1 , T 2 and PD maps with 1 mm 3 resolution could be obtained in 7.5 min. Conclusions 3D MRF stack-of-spirals acquisition with hybrid SW + GRAPPA reconstruction may provide a feasible approach for rapid, high-resolution quantitative whole-brain imaging. Highlights Combination of sliding-window and GRAPPA allows highly accelerated 3D MRF. High-resolution (1 mm 3 ) whole-brain multi-parameter maps obtained in 7.5-min. Compared to 2D, 3D MRF enables higher SNR for accurate, isotropic resolution maps. Graphical abstract [DISPLAY OMISSION]


  • 주제어

    MR fingerprinting .   Quantitative imaging .   High resolution .   GRAPPA.  

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