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Seizure : European journal of Epilepsy v.53, 2017년, pp.13 - 17   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Potential factors impacting health-related quality of life among patients with epilepsy: Results from the United Arab Emirates

Alsaadi, Taoufik (American Center for Psychiatry & Neurology, Abu Dhabi, United Arab Emirates ) ; Kassie, Seada (American Center for Psychiatry & Neurology, Abu Dhabi, United Arab Emirates ) ; El Hammasi, Khadija (Department of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, United Arab Emirates ) ; Shahrour, Tarek M. (Department of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, United Arab Emirates ) ; Shakra, Mustafa (Department of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, United Arab Emirates ) ; Turkawi, Lamya (Department of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, United Arab Emirates ) ; Nasreddine, Wassim (Department of Neurology, American University of Beirut-Medical center 7, Lebanon, Lebanon ) ; Raoof, Mufeed (Department of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi, United Arab Emirates ) ;
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    Abstract Purpose to investigate potential factors impacting HRQOL among PWE at a medical facility in the UAE. Methods Depression, anxiety, and health-related quality of life were assessed in 160 adult patients with epilepsy from September 2014 to January 2015 at Sheikh Khalifa Medical City (SKMC). The World Health Organization Quality of Life abbreviated scale (WHOQOL-BREF), the Patient Health Questionnaire nine-item (PHQ-9) depression scale, and Generalized Anxiety Disorder seven-item (GAD-7) scale were administered. Demographic details including psychosocial factors were also obtained. Clinical details including seizure freedom, epilepsy type, epilepsy duration, and magnetic resonance imaging (MRI) results were recorded. Multivariate analysis was used to look at significant variables associated with HRQOL. Results Depression, anxiety, seizure freedom, and the use of anti-depressants had significant positive correlation with HRQOL in univariate analysis. However, depression, followed by seizure freedom, had the strongest association with HRQOL in a multivariate regression analysis. Conclusion Depression and seizure freedom, followed by anxiety and anti-depressants use, were significantly correlated with HRQOL. These results underscore the importance of screening for psychiatric comorbidities in patients with epilepsy. Implications Screening for comorbid psychiatric disorders should be an essential component of the standard of care, and incorporated in the treatment plan for all patients with epilepsy. Factors contributing to psychiatric symptoms among PWE, such as maladaptive illness perceptions, non-adherence to anti-epileptic drugs (AED), and social stigma should be carefully addressed to achieve an optimal health-care plan.


  • 주제어

    Epilepsy .   Depression .   Anxiety .   Quality of life in epilepsy .   UAE.  

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