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Comprehensive psychiatry v.80, 2018년, pp.57 - 64   SCI SCIE SSCI
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Features of mood associated with high body weight in females with fibromyalgia

Alciati, Alessandra    (Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy   ); Atzeni, Fabiola    (IRCCS Galeazzi Orthopedic Institute, Milan, Italy   ); Grassi, Massimiliano    (Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy   ); Caldirola, Daniela    (Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy   ); Sarzi-Puttini, Piercarlo    (Rheumatology Unit, ASST-Fatebenefratelli-L, Sacco University Hospital, Milan, Italy   ); Angst, Jules    (Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Switzerland   ); Perna, Giampaolo    (Department of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, FoRiPsi, Albese con Cassano, Como, Italy  );
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    Abstract Background Fibromyalgia (FM) is a common syndrome whose main characteristic is chronic widespread musculoskeletal pain, the severity of which is frequently worsened by concomitant obesity. Major depression (MD), particularly as part of a bipolar spectrum disorder (BSD), is associated with both obesity and FM. Objective To evaluate the relationship between lifetime MD, hypomanic symptoms and the body mass index (BMI) in patients with FM. Method Of the 115 patients originally screened, 87 women with FM finally entered the study. Forty-nine patients (57%) had a lifetime diagnosis of MD, assessed by a structured clinical interview based on DSM-IV criteria, and four of them (4.6%) had a current MD episode. Lifetime hypomanic symptoms were measured by means of the self-rated Hypomania Checklist. According to the international criteria for BMI, FM patients were classified as under/normal-weight (61%), overweight (30%) and obese (9%). Results 62 patients (71.2%) with FM had a bipolar spectrum disorder (BSD). Thirty (48.3%) of them met criteria for bipolar II disorder, 32 (51,6%) for bipolar disorder NOS (18 FM patients with MD associated to sub-syndromal hypomanic syndrome and 14 with hypomanic syndrome without MD). No patient had a bipolar I disorder. Only one patient met the criteria for a major depressive disorder (MDD). There was no significant difference in mean BMI between the patients with and without a lifetime diagnosis of MD, but there was a positive association between the level of hypomanic symptoms and BMI values (p Conclusions Our finding adds to previous evidence indicating that hypomanic symptoms are a central feature of FM. In the case of the early identification of high-level hypomanic symptoms, body weight should be closely monitored in order to prevent obesity and its detrimental impact on females with FM.


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