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Fibromatosis, a benign breast disease mimicking carcinoma. A case report

Ashoor, Arwa (Breast Unit, Department of Surgery, King Fahd General Hospital, P. O. Box: 51652, Jeddah, 21553, Saudi Arabia ) ; Monti, Simonetta (Senology Division, European Institute of Oncology, Milan, Italy ) ; Pezzella, Modestino (General Surgery VIII, Polyclinic of Naples, Naples, Italy ) ;
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    Abstract Introduction Fibromatosis is an uncommon breast lesion that can mimic breast carcinoma in its clinical presentation. Case summary We present a clinical case in which a diagnosis and treatment dilemma existed, in terms of ultrasound findings that were not clear and suspicious, as well as results of Fine needle aspiration cytology. Our findings are compared with previous published cases. Also, literature review regarding fibromatosis presentation and diagnosis has been discussed, as well as treatment options. Conclusion Management of breast fibromatosis remains controversial because of the low incidence and further efforts needed to establish evidence-based treatment guidelines. Highlights Fibromatosis is an infiltrating histologically low grade spindle cell proliferation composed of fibroblastic cells with a variable amount of collagen. The treatment of choice for breast fibromatosis; is primary surgical excision with clean margins. It is characterized by being locally aggressive but not metastasizing. Fibromatosis has a high rate of recurrence after surgical excision. Management of recurrent breast fibromatosis remains controversial because of the low incidence and, in consequence, the limited data.


  • 주제어

    Breast disease .   Benign breast lesion mimicking cancer .   Benign breast disease .   Case report .   Fibromatosis.  

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