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Mechanolytic management of transcatheter aortic valve thrombosis

Sharif-Yakan, Ahmad (Division of Cardiology, Department of Internal Medicine, University Hospital Rostock, Rostock, Germany ) ; Aboukoura, Mohamad (Division of Cardiology, Department of Internal Medicine, University Hospital Rostock, Rostock, Germany ) ; Nienaber, Christoph A. (Division of Cardiology, Department of Internal Medicine, University Hospital Rostock, Rostock, Germany ) ;
  • 초록  

    Abstract Data on the incidence, characteristics, and treatment of thrombosis of a transcatheter aortic valve implantation (TAVI) implant are scarce. We report a challenging case of a TAVI thrombosis occurring 6months after the procedure. Initial anticoagulation using low-molecular-weight heparin followed by thrombolytic therapy failed to both relieve symptoms and alleviate thrombosis. However, the condition of the patient deteriorated rapidly, necessitating the use of balloon valvuloplasty followed by low-dose thrombolysis. The uniqueness of the case can be summarized as follows: (1) first report of balloon valvuloplasty to manage a case of TAVI thrombosis; (2) thrombolytic therapy after balloon valvuloplasty was successful to further reduce gradient from valve thrombosis. Highlights First case reporting the use of balloon valvuloplasty to manage a case of transcatheter aortic valve implantation (TAVI) thrombosis. Thrombolytic therapy was successfully combined with mechanical valvuloplasty to manage a severe TAVI valve thrombosis otherwise resistant to initial therapeutic anticoagulation and thrombolysis.


  • 주제어

    Valvuloplasty .   Thrombosis .   Bioprosthesis .   Anticoagulation.  

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