Wound dressings from naturally-occurring polymers: A review on homopolysaccharide-based composites
Abstract Wound dressings are designed to support the wound bed and protect it from the factors that may delay or impede its healing such as contaminations and moisture-loss, thereby facilitating and accelerating the healing process. The materials used to prepare wound dressings include natural and synthetic polymers, as well as their combinations, in the forms of films, sponges and hydrogels. Polysaccharides are naturally-occurring polymers that have been extensively used as wound dressing materials. Homopolysaccharides are a class of polysaccharides consist of only one type of monosaccharide. The current review intends to overview the studies in which wound dressings from naturally-occurring polymers, based on homopolysaccharides, were prepared and evaluated. Homopolysaccharides such as cellulose, chitosan, chitin, pullulan, starch and β-glucan were considered. Highlights Naturally-occurring polymers receive renewed attention as highly biocompatible and environmentally friendly materials. They are chosen for wound dressing because of their similarity to extracellular matrix and good acceptance by the biological systems. Naturally-occurring polysaccharides are the polymers offering good hemocompatibility and lower cost than other biopolymers. Polysaccharides containing one monosaccharide are homopolysaccharides, whereas those containing more are known as heteropolysaccharides. The homopolysaccharide-/heteropolysaccharide-based wound dressings may contain inorganic materials, antibiotics or medicinal plants.
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