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Revista española de cardiología v.71 no.4, 2018년, pp.250 - 256   SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

El consumo mAximo de oxIgeno predice los ingresos recurrentes por insuficiencia cardiaca con fracciOn de eyecciOn conservada
Peak Exercise Oxygen Uptake Predicts Recurrent Admissions in Heart Failure With Preserved Ejection Fraction

Palau, Patricia (Servicio de Cardiología, Hospital General Universitario de Castellón, Universitat Jaume I, Castellón, Spain ) ; Domínguez, Eloy (Servicio de Cardiología, Hospital General Universitario de Castellón, Universitat Jaume I, Castellón, Spain ) ; Núñez, Eduardo (Servicio de Cardiología, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain ) ; Ramón, José (Servicio de Cardiología, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain ) ; María (Departamento de Fisioterapia, Universitat de València, Valencia, Spain ) ; López, Laura (Servicio de Cardiología, Hospital General Universitario de Castellón, Universitat Jaume I, Castellón, Spain ) ; Melero, Joana (Servicio de Cardiología, Hospital Clínico Universitario, INCLIVA, Universitat de València, Valencia, Spain ) ; Sanchis, Juan (Servicio de Cardiología, Hospital General Universitario de Castellón, Universitat Jaume I, Castellón, Spain ) ; Bellver, Alejandro (Servic ) ; Santas, Enrique ; Bayes-Genis, Antoni ; Chorro, Francisco J. ; Núñez, Julio ;
  • 초록  

    Abstract Introduction and objectives Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent syndrome with an elevated risk of morbidity and mortality. To date, there is scarce evidence on the role of peak exercise oxygen uptake (peak VO 2 ) for predicting the morbidity burden in HFpEF. We sought to evaluate the association between peak VO 2 and the risk of recurrent hospitalizations in patients with HFpEF. Methods A total of 74 stable symptomatic patients with HFpEF underwent a cardiopulmonary exercise test between June 2012 and May 2016. A negative binomial regression method was used to determine the association between the percentage of predicted peak VO 2 (pp-peak VO 2 ) and recurrent hospitalizations. Risk estimates are reported as incidence rate ratios. Results The mean age was 72.5 ± 9.1 years, 53% were women, and all patients were in New York Heart Association functional class II to III. Mean peak VO 2 and median pp-peak VO 2 were 10 ± 2.8mL/min/kg and 60% (range, 47-67), respectively. During a median follow-up of 276 days [interquartile range, 153-1231], 84 all-cause hospitalizations in 31 patients (41.9%) were registered. A total of 15 (20.3%) deaths were also recorded. On multivariate analysis, accounting for mortality as a terminal event, pp-peak VO 2 was independently and linearly associated with the risk of recurrent admission. Thus, and modeled as continuous, a 10% decrease of pp-peak VO 2 increased the risk of recurrent hospitalizations by 32% (IRR, 1.32; 95%CI, 1.03-1.68; P = .028). Conclusions In symptomatic elderly patients with HFpEF, pp-peak VO 2 predicts all-cause recurrent admission.


  • 주제어

    Heart failure with preserved ejection fraction .   Prognosis .   Recurrent hospitalizations .   Exercise capacity .   Insuficiencia cardiaca con fracción de eyección conservada .   Pronóstico .   Ingresos recurrentes .   Capacidad funcional.  

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