Reinforcing effect of graphene oxide reinforcement on the properties of poly (vinyl alcohol) and carboxymethyl tamarind gum based phase-separated film
Abstract The current study deals with the preparation and the characterization of the PVA-CMT-GO films. The PVA-CMT film was translucent in nature and smooth to touch. The addition of GO resulted in the formation of agglomerated structures. XRD studies suggested that the incorporation of GO increased the average crystallite size. The mechanical properties of the films as determined by stress relaxation studies suggested that all the films were viscoelastic in nature. The drug release study showed a decrease in the amount of the drug release with the increase in the GO content. The PVA-CMT-GO films (without drug) showed certain degree of antimicrobial activity owing to the inherent antimicrobial property of GO. The drug loaded films also showed good antimicrobial property. It was found that the prepared films altered the cell proliferation of the human skin keratinocytes in a composition-dependent manner. Highlights Poly(vinyl alcohol) (PVA)-carboxymethyl tamarind (CMT) gum film was prepared. PVA-CMT film was reinforced with graphene oxide (GO) in varied proportions. GO reinforced films showed larger crystallite size and antimicrobial property. Viscoelastic nature of the films were estimated from stress relaxation study. Cell proliferation of keratinocytes was altered by the presence of GO. Graphical abstract [DISPLAY OMISSION]
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