본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Journal of the mechanical behavior of biomedical materials v.81, 2018년, pp.142 - 148   SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Preparation and biocompatibility evaluation of polypropylene mesh coated with electrospinning membrane for pelvic defects repair

Lu, Yao (Faculty of Healthcare Equipment, Zhejiang Pharmaceutical College, Ningbo 315000, Zhejiang Province, China ) ; Fu, Shaoju (Key Laboratory of Textile Science and Technology, Ministry of Education, Donghua University, Shanghai 201620, China ) ; Zhou, Shuanglin (Faculty of Healthcare Equipment, Zhejiang Pharmaceutical College, Ningbo 315000, Zhejiang Province, China ) ; Chen, Ge (Medical Engineering Department, The first People's hospital of Ningbo, Ningbo 315000, Zhejiang Province, China ) ; Zhu, Chaoting (Faculty of Healthcare Equipment, Zhejiang Pharmaceutical College, Ningbo 315000, Zhejiang Province, China ) ; Li, Nannan (Faculty of Healthcare Equipment, Zhejiang Pharmaceutical College, Ningbo 315000, Zhejiang Province, China ) ; Ma, Ying (Faculty of Healthcare Equipment, Zhejiang Pharmaceutical College, Ningbo 315000, Zhejiang Province, China ) ;
  • 초록  

    Abstract Composite mesh with different materials composition could compensate for the drawbacks brought by single component mesh. Coating a membrane layer on the surface of macroporous mesh is a common method for preparing composite medical mesh. Electrospinning and dipping methods were introduced to form the two kinds of membrane-coated PP meshes (electro-mesh and dip-mesh); several properties were measured based on subcutaneous implantation model in rat. The results revealed that continuous tissue ingrowth could be observed for electro-mesh only with evidences of strength increase (electro-mesh: 0 week − 13.1 ± 0.88 N, 2 week − 16.87 ± 1.39 N, 4 week − 22.04 ± 2.05 N) and thickness increase (electro-mesh: 0 week − 0.437 ± 0.023 mm, 2 week − 0.488 ± 0.025 mm, 4 week − 0.576 ± 0.028 mm). However, no tissues were observed for dip-mesh in the first 2 weeks, both on macroscopic level and microscopic level, proved by strength data (dip-mesh: 0 week − 13.36 ± 1.06 N, 2 week − 13.4 ± 1.33 N, 4 week – 18.61 ± 1.89 N) and thickness data (dip-mesh: 0 week − 0.439 ± 0.018 mm, 2 week − 0.439 ± 0.019 mm, 4 week − 0.502 ± 0.032 mm). Electro-mesh had larger surface area decrease (10.74 ± 1.22%) than that of dip-mesh (2.78 ± 0.52%). The adhesion level of electro-mesh (medium adhesion) was also higher than that of dip-mesh (mild adhesion). Even if showing differences in several properties, both meshes were similar under histological observation, with the ability to support fresh tissues ingrowth. Considering operation environment, electro-mesh seems more suitable than dip-mesh with a rapid tissue growing, medium adhesion rate for repairing pelvic floor defects.


  • 주제어

    Pelvic floor .   Composite mesh .   Electrospinning .   Biocompatibility.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기