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Anaerobe v.51, 2018년, pp.61 - 63   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Rodents are carriers of Clostridioides difficile strains similar to those isolated from piglets

de Oliveira Jr., Carlos Augusto    (Veterinary School, Federal University of Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, 31.270-901, Belo Horizonte, MG, Brazil   ); de Paula Gabardo Jr., Michelle    (Veterinary School, Federal University of Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, 31.270-901, Belo Horizonte, MG, Brazil   ); Guedes Jr., Roberto Maurício Carvalho    (Veterinary School, Federal University of Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, 31.270-901, Belo Horizonte, MG, Brazil   ); Poncet Jr., Fabrice    (Hospital Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland   ); Blanc Jr., Dominique S.    (Hospital Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland   ); Lobato Jr., Francisco Carlos Faria    (Veterinary School, Federal University of Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, 31.270-901, Belo Horizonte, MG, Brazil   ); Silva Jr., Rodrigo Otávio Silveira    (Veterinary School, Federal University of Minas Gerais (UFMG), Antônio Carlos Avenue, 6627, 31.270-901, Belo Horizonte, MG, Brazil  );
  • 초록  

    Abstract Features of Clostridioides difficile transmission in swine and the role of rodents as C. difficile reservoir are not clear. To investigate if rodents can carry strains of C. difficile that are genetically similar to those isolated from swine, 97 fecal samples from neonatal piglets and 41 intestinal contents from rodents were collected in two farms. All samples were subjected to C. difficile culture and the presence of A/B toxins in piglet feces were accessed by commercial enzyme imunoassay (EIA). C. difficile isolates were typed by double- (DLST) and multi-locus sequence typing (MLST). C. difficile was isolated from 15.5% of piglets and 31.7% of rodents. Most isolates were identified as DLST type 4-4 and 17-5 (both are ST11), which were found in both rodents and piglets. Results of this study suggested that rodents may have a role on the transmission and spread of C. difficile strains to swine. Highlights The role of rodents as C. difficile reservoir for piglets is not clear. C. difficile isolates from rodents and piglets from the same farms were submitted to MLST and DLST. Most isolates were identified as DLST types 4-4 and 17-5, both are (MLST) ST11. Rodents may have a role on the transmission and spread of C. difficile strains to piglets.


  • 주제어

    Clostridium difficile .   Mice .   Rats .   Mus musculus .   Rattus rattus.  

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