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British journal of surgery : BJS v.105 no.9, 2018년, pp.1163 - 1170  

Morbidity and mortality according to age following gastrectomy for gastric cancer

Nelen, S. D. (Department of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands ) ; Bosscha, K. (Department of Surgery, Jeroen Bosch Hospital, 's‐Hertogenbosch, The Netherlands ) ; Lemmens, V. E. P. P. (Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands ) ; Hartgrink, H. H. (Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands ) ; Verhoeven, R. H. A. (Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), Utrecht, The Netherlands ) ; de Wilt, J. H. W. (Department of Surgery, Radboud University Medical Centre, Nijmegen, The Netherlands ) ;
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    Background This study investigated age‐related differences in surgically treated patients with gastric cancer, and aimed to identify factors associated with outcome. Methods Data from the Dutch Upper Gastrointestinal Cancer Audit were used. All patients with non‐cardia gastric cancer registered between 2011 and 2015 who underwent surgery were selected. Patients were analysed by age group (less than 70 years versus 70 years or more). Multivariable logistic regression was used to assess the influence of clinicopathological factors on morbidity and mortality. Results A total of 1109 patients younger than 70 years and 1206 aged 70 years or more were included. Patients aged at least 70 years had more perioperative or postoperative complications (41·2 versus 32·5 per cent; P versus 3·2 per cent; P Conclusion ASA grade, neoadjuvant chemotherapy and type of resection are independent predictors of morbidity and death in patients with gastric cancer, irrespective of age.


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