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Journal of cellular physiology v.233 no.10, 2018년, pp.6509 - 6522  

Bone tissue engineering: Adult stem cells in combination with electrospun nanofibrous scaffolds

Moradi, Sadegh L. (Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran ) ; Golchin, Ali (Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran ) ; Hajishafieeha, Zahra (Department of Microbiology, Qazvin University of Medical Sciences, Qazvin, Iran ) ; Khani, Mohammad‐Mehdi (Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran ) ; Ardeshirylajimi, Abdolreza (Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran ) ;
  • 초록  

    Since bone tissue lesions caused by several reasons and has global outbreak without any attentions to the modernity level of the countries. In the other hands treatment of patients with this problem faced to the several limitations, in this because the future of the bone lesions treatments is related to the future of the bone tissue engineering. This review tries to cover the most suitable stem cells and materials from either natural or synthetic sources for bone tissue engineering. These understanding points would help researchers to further uncover the application of different adult stem cell sources in electrospinning scaffolds, promotion of nanofibrous composite construct design and adult stem cell type selection to enhance cell function and bone tissue engineering, and link laboratory investigations to clinical applications.


  • 주제어

    bone tissue engineering .   fabrication .   natural biopolymers .   regenerative medicine and adult stem cells .   synthetic biopolymers.  

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