본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Scandinavian journal of medicine & science in sports v.28 no.8, 2018년, pp.1925 - 1933   SCI SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Altered stress hormone response following acute exercise during prostate cancer treatment

Hanson, E. D. (Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC, USA ) ; Sakkal, S. (Institute for Health and Sport, Victoria University, Melbourne, Vic., Australia ) ; Evans, W. S. (Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC, USA ) ; Violet, J. A. (Division of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, East Melbourne, Vic., Australia ) ; Battaglini, C. L. (Department of Exercise & Sport Science, University of North Carolina, Chapel Hill, NC, USA ) ; McConell, G. K. (Institute for Health and Sport, Victoria University, Melbourne, Vic., Australia ) ; Hayes, A. (Institute for Health and Sport, Victoria University, Melbourne, Vic., Australia ) ;
  • 초록  

    Exercise training reduces the side effects of cancer treatments; however, the stress hormone response to acute exercise during prostate cancer (PCa) treatment is unclear. The study purpose was to examine the effects of acute exercise on circulating cortisol, epinephrine (Epi), and norepinephrine (NE) concentrations during PCa treatment with and without androgen deprivation therapy (ADT). Men with PCa (n = 11), with PCa on ADT (n = 11), and with non‐cancer controls (n = 8) had blood samples for stress hormones collected before and immediately (0 hour), 2 hours, and 24 hours after 45 minutes of intermittent cycling at 60% of peak wattage. NE increased by 385% ( P .001) at 0 hour and remained elevated at 2 hours ( P .05) with no group differences. Overall, cortisol significantly increased at 0 hour (36%, P .012) and then significantly decreased below baseline at 2 hours (−24%, P .001) before returning to resting levels at 24 hours. Cortisol levels during ADT were 32% lower than PCa ( P =< .006) with no differences vs controls. Epi increased immediately after exercise more in controls (817%, P .001) than with ADT (700%) and PCa (333%) patients, and both cancer groups’ absolute levels were attenuated relative to controls (ADT: −54%, PCa: −52%, P =< .004). Compared with age‐matched controls, PCa and ADT patients exhibited similar stress hormone responses with acute exercise for NE and cortisol but an attenuated EPI response that suggests altered adrenal function. Future studies should examine the physical stress of multiple exercise bouts to verify these findings and to explore the functional hormonal effects, such as immune and metabolic responses, during cancer treatment.


  • 주제어

    acute exercise .   androgen deprivation therapy .   catecholamines .   cortisol .   stress response.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기