본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

The breast journal v.24 no.4, 2018년, pp.567 - 573   SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Does response to neo‐adjuvant chemotherapy impact breast reconstruction?

Cassidy, Michael R. (Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA ) ; Zabor, Emily C. (Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA ) ; Stempel, Michelle (Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA ) ; Mehrara, Babak (Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA ) ; Gemignani, Mary L. (Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA ) ;
  • 초록  

    Abstract Neo‐adjuvant chemotherapy (NAC) is administered in breast cancer treatment for downstaging of disease. Here, we determined the impact of response to NAC on breast reconstruction uptake. A prospective NAC and mastectomy database with or without reconstruction were reviewed with IRB approval. Univariable analyses were conducted using Kruskal‐Wallis or Fisher's exact tests. Multivariable logistic regression was used to adjust for potential confounders. We identified 271 patients with unilateral breast cancer receiving NAC and either unilateral or bilateral mastectomy from 9/2013 to 5/2016. Seventy patients (25.8%) had a pCR to NAC. One hundred and seventy‐five patients (64.6%) had immediate reconstruction (IR), and 96 had no IR. On univariable analysis, younger age ( P P P P = .006) were significantly associated with higher IR rates. On multivariable analysis, pCR ( P = .792) and tumor subtype ( P = 0.061) were not significantly associated with IR; T‐stage was significantly associated with IR ( P P = .048) but was not associated with reconstruction type (tissue expander versus autologous, P = 1.0) among 175 patients who had IR. In patients who have mastectomy after NAC, IR is influenced by age, T‐stage at presentation, and choice of bilateral mastectomy, but not by response to NAC. A subset of patients who are young, with earlier T‐stage and pCR, is more likely to proceed with bilateral mastectomy.


  • 주제어

    breast cancer .   breast reconstruction .   neo‐adjuvant chemotherapy.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
  • 원문이 없습니다.
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기