본문 바로가기
HOME> 논문 > 논문 검색상세

논문 상세정보

Journal of gynecologic oncology : jgo v.29 no.3, 2018년, pp.e37 -    SCIE
본 등재정보는 저널의 등재정보를 참고하여 보여주는 베타서비스로 정확한 논문의 등재여부는 등재기관에 확인하시기 바랍니다.

Retrospective analysis of sites of recurrence in stage I epithelial ovarian cancer

Hirose, Sou    (Department of Obstetrics and Gynecology, The Jikei University Kashiwa Hospital, Kashiwa, Japan .  ); Tanabe, Hiroshi    (Department of Obstetrics and Gynecology, The Jikei University Kashiwa Hospital, Kashiwa, Japan .  ); Nagayoshi, Youko    (Department of Obstetrics and Gynecology, The Jikei University School of Medicine, Tokyo, Japan .  ); Hirata, Yukihiro    (Department of Obstetrics and Gynecology, The Jikei University Katsushika Medical Center, Tokyo, Japan .  ); Narui, Chikage    (Department of Obstetrics and Gynecology, The Jikei University Daisan Hospital, Tokyo, Japan .  ); Ochiai, Kazuhiko    (Department of Obstetrics and Gynecology, The Jikei University Katsushika Medical Center, Tokyo, Japan .  ); Isonishi, Seiji    (Department of Obstetrics and Gynecology, The Jikei University Daisan Hospital, Tokyo, Japan .  ); Takano, Hirokuni    (Department of Obstetrics and Gynecology, The Jikei University Kashiwa Hospital, Kashiwa, Japan .  ); Okamoto, Aikou  
  • 초록

    Objective The aim of the study is to investigate recurrence of stage I epithelial ovarian cancer. Methods Six hundred two patients diagnosed with stage I epithelial ovarian cancer at 4 hospitals between 2000 and 2013 were retrospectively analyzed. Age, surgical procedure, substage, histologic type, adjuvant chemotherapy, recurrence, initial recurrence site (peritoneal dissemination [P], hematogenous recurrence [H], lymphogenous recurrence [L], and others [O]), and frequency of recurrence at each site were investigated retrospectively. Results Median age was 54 years and median follow-up was 60 months. The stage was IA in 180 cases (30%), IB in 8 (1%), IC1 in 247 (41%), IC2 in 63 (10%), and IC3 in 104 (17%). Systematic lymph node dissection including both pelvic and para-aortic lymph nodes was performed in 224 patients (37%), and 412 patients (68%) received adjuvant chemotherapy. Recurrence occurred in 70 patients (11.6%). The median time to recurrence was 18 months, and the stage was IA in 13 (19%), IB in 1 (1%), IC1 in 24 (34%), IC2 in 9 (13%), and IC3 in 23 (33%) cases. The numbers of recurrence at the P, H, L, and O sites, including overlapping cases, were 49 (70%), 18 (26%), 9 (13%), and 6 (9%), respectively, and recurrence by peritoneal dissemination in the pelvis occurred in 43 cases (61%). Conclusion Recurrence of stage I epithelial ovarian cancer by peritoneal dissemination was frequent, especially in the pelvis. There is a need to elucidate the pathogenesis of peritoneal recurrence and to prepare a treatment strategy to prevent pelvic peritoneal recurrence.


  • 주제어

    Ovarian Neoplasms .   Recurrence .   Neoplasm Metastasis .   Neoplasm Seeding.  

 활용도 분석

  • 상세보기

    amChart 영역
  • 원문보기

    amChart 영역

원문보기

무료다운로드
유료다운로드

유료 다운로드의 경우 해당 사이트의 정책에 따라 신규 회원가입, 로그인, 유료 구매 등이 필요할 수 있습니다. 해당 사이트에서 발생하는 귀하의 모든 정보활동은 NDSL의 서비스 정책과 무관합니다.

원문복사신청을 하시면, 일부 해외 인쇄학술지의 경우 외국학술지지원센터(FRIC)에서
무료 원문복사 서비스를 제공합니다.

NDSL에서는 해당 원문을 복사서비스하고 있습니다. 위의 원문복사신청 또는 장바구니 담기를 통하여 원문복사서비스 이용이 가능합니다.

이 논문과 함께 출판된 논문 + 더보기