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저널/프로시딩 상세정보

권호별목차 / 소장처보기

H : 소장처정보

T : 목차정보

Yonsei medical journal 12건

  1. [국내논문]   New therapeutic techniques and strategies in pulmonary rehabilitation.  

    Bach, J R , Lee, H J
    Yonsei medical journal v.34 no.3 ,pp. 201 - 211 , 1993 , 0513-5796 ,

    초록

    Patients with chronic obstructive pulmonary disease (COPD) or those with paralytic restrictive pulmonary syndromes caused by progressive neuromuscular disease, kyphoscoliosis or traumatic quadriplegia may require frequent hospitalization because of respiratory impairment and have increased morbidity and mortality. Pulmonary rehabilitation has been shown to decrease the frequency of hospitalization, ameliorate symptoms, increase exercise tolerance, and in one study, prolong life for individuals with COPD. It is now recognized that principles of pulmonary rehabilitation can also be used to avoid hospitalization, intubation, tracheostomy and bronchoscopy while enhancing quality of life, decreasing cost, and greatly prolonging life for individuals with paralytic restrictive syndromes and global alveolar hypoventilation as well.

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  2. [국내논문]   Smoking and total mortality: Kangwha cohort study, 6-year follow-up.  

    Kim, I S , Ohrr, H , Jee, S H , Kim, H , Lee, Y
    Yonsei medical journal v.34 no.3 ,pp. 212 - 222 , 1993 , 0513-5796 ,

    초록

    The relationship between smoking and total mortality was examined in a community residents population sample of 2,848 men and 3,543 women aged 55 years or over in Kangwha County, Korea during 1985-1991. A total of 1,436 deaths occurred during a 6-year follow-up among the 1.3 fold-higher in current smokers than in non-smokers among men. The relative risk of total mortality was highest for the 55-59 year old age group both in ex-smokers and in current smokers. PAR for total mortality attributed by smoking were estimated to be 26% for ex-smokers and 25% for current smokers in men. The biggest RR (2.1) and PAR (49%) were observed among those who smoked less than 19 cigarettes per day compared to non-smokers in males. Smokers who began to smoke at age 18 or before showed RR 1.8, and PAR 38% in men. Smoking was the most important variable related with total mortality second only to hypertensiveness not including preventable ones among men in multivariate analyses. Men who began to smoke at nineteen years of age or before had RR 1.5 for total cancer mortality. Women showed the similar picture as males in risk factors composition and in relative risks, with a low association strength, however.

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  3. [국내논문]   The effect of smoking on health service utilization.  

    Jee, S H , Kim, I S , Suh, I
    Yonsei medical journal v.34 no.3 ,pp. 223 - 233 , 1993 , 0513-5796 ,

    초록

    This study involved direct observation of the differences in prevalence of disease and utilization of medical care by smokers, non-smokers, and ex-smokers. The data was collected from the 1989 Korean National Health Survey (1989 KNHS). A total of 5,201 individuals ages 20 to 59 were randomly selected from the whole Korean population using the three-stage stratified random sampling. Based on the logistic regression, the following results were obtained. Compared with the non-smokers, the relative risks for an acute disease were 1.9 and 1.7 for male ex-smokers and female current smokers, respectively. Smoking behavior significantly increased utilization of health services such as admissions (RR = 2.5 for current smokers) among females, outpatient visits (RR = 2.1 for ex-smokers, RR = 2.3 for age began to smoke was less than 18 years) among males and (RR = 1.5 for current smokers) among females. Furthermore, the utilization of outpatient services for ex-smokers who were self-concerned about their health was 3.4 times higher than the non-smokers. Based on the weighted least square regression model the days of medication for male current smokers and ex-smokers were significantly longer than non-smokers. These effects persisted after controlling for major identified confounding factors. Thus, the results of this study confirmed that smoking is an important cause of diseases and a major contributing factor to the use of health services.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  4. [국내논문]   The fibrinogen degradation products (FgDP) levels in liver disease.  

    Song, K S , Kim, H S , Park, K E , Kwon, O H
    Yonsei medical journal v.34 no.3 ,pp. 234 - 238 , 1993 , 0513-5796 ,

    초록

    We measured plasma levels of fibrinogen degradation products (FgDP) with newly developed enzyme-linked immunosorbent assay based on monoclonal antibody to assess the fibrinogenolytic state in 52 patients with various liver diseases (27 patients with liver cirrhosis, 10 with chronic hepatitis, 7 with acute hepatitis, 6 with hepatocellular carcinoma, 2 with intrahepatic cholestasis). As compared with 20 healthy subjects (upper limit: 580 ng/ml), elevated plasma levels (660-32000 ng/ml) of FgDP were found in 19 (36.5%) patients. When analyzed according to the underlying disease categories, the magnitude of elevations of FgDP were most prominent in patients with chronic hepatitis. No correlation was found between plasma FgDP levels and serum AST or ALT activity. These findings indicate that increased primary fibrinogenolysis is not rare in liver disease, but poorly correlates with liver function.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  5. [국내논문]   The prevalence study on restriction fragment length polymorphism analysis for the detection of hemophilia A carrier.  

    Song, K S , Lee, C H , Chung, C S , Lee, K , Yang, Y H , Kim, K Y
    Yonsei medical journal v.34 no.3 ,pp. 239 - 242 , 1993 , 0513-5796 ,

    초록

    We have analyzed two (BclI and XbaI) intragenic restriction fragment length polymorphisms (RFLPs) and St14 (DXS52) variable number of tandem repeats (VNTR) by rapid PCR method in 97 unrelated normal subjects. The incidences for positive Bc1I and XbaI polymorphic sites in the Koreans were 81% and 72%, respectively, which were higher than other ethnic groups but similar to that reported in the Chinese or Japanese, giving the heterozygosity rate of 0.32 and 0.40, respectively. The amplified allele size was 880 bp with no other polymorphism in the analysis of St14 (DXS52) VNTR. This finding should be taken into account in the planning of a prenatal diagnosis program for ethnic Koreans.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  6. [국내논문]   Percutaneous mitral balloon valvuloplasty in patients with restenosis after surgical commissurotomy: a comparative study.  

    Ha, J W , Shim, W H , Yoon, J H , Jang, Y S , Chung, N S , Cho, S Y , Kim, S S , Lee, W K
    Yonsei medical journal v.34 no.3 ,pp. 243 - 247 , 1993 , 0513-5796 ,

    초록

    We performed percutaneous mitral balloon valvuloplasty (PMV) in 367 patients to compare the effectiveness of PMV between patients with mitral restenosis after surgical commissurotomy (group 1) and patients with unoperated mitral stenosis (group 2). Twenty-two had undergone closed or open mitral commissurotomy 11.2 years before. There were no significant differences in clinical profiles between the two groups. The mitral valve area was increased from 1.0 +/- 0.8 to 1.8 +/- 0.6 cm2 in group 1 and 0.9 +/- 0.3 to 2.0 +/- 0.7 cm2 in group 2 (p > 0.05). The mitral gradient was decreased from 14 +/- 5.9 to 6 +/- 2.6 mmHg in group 1 and 18 +/- 7.0 to 7 +/- 5.3 mmHg in group 2 (p > 0.05). The increment of mitral regurgitation and significant left to right shunt after PMV were not significantly different (10% versus 14.7%, 5% versus 10.4% respectively). Optimal results were attained in 75% of the patients in group 1 and in 84.3% of the patients in group 2 (p > 0.05). These results suggest PMV in mitral restenosis after surgical commissurotomy may be safe in selected patients and may be equally effective as in unoperated mitral stenosis.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  7. [국내논문]   Detection of specific serum IgE in clonorchiasis cases and analysis of Clonorchis sinensis allergens.  

    Yong, T S , Kim, D S , Lee, S Y , Im, K I , Lee, K Y
    Yonsei medical journal v.34 no.3 ,pp. 248 - 257 , 1993 , 0513-5796 ,

    초록

    Specific serum IgE levels of Clonorchis sinensis in infected humans were measured by avidin-biotin ELISA, and allergens from C. sinensis were identified by immunoblot and autoradiography. Then, allergens fractionated by Sephadex G-200 gel filtration were analyzed, and cross-reactive allergenic components of C. sinensis reacted with paragonimiasis sera were revealed. Fourteen out of 15 C. sinensis egg-positives were found to be serum IgE positive (absorbance > 0.27). Of 14 IgE-reacting allergen bands visualized, major allergens of 66, 61.5, 45, 37, 28.5, 23.5 and 15.5 KD were recognized by more than 50% of the sera of infected humans. The considerable individual variations of IgE immune responses to C. sinensis allergenic components were also noticed. C. sinensis extract was separated into 5 fractions by Sephadex G-200 gel filtration. Seventy-four KD allergen was recognized in the first fraction, 50, 45, 37, 29.5 and 28.5 KD in the third, and 15.5 KD in the fourth. Cross-reactive allergens with sera of paragonimiasis cases were identified as 66, 45, 28.5, 13 and 7.5 KD.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [국내논문]   Effect of polyadenylic.polyuridylic acid on cellular responses of peripheral blood mononuclear cells from patients with chronic active hepatitis B.  

    Kim, W H , Hahm, K B , Park, S J , Kang, J K , Park, I S , Choi, H J , Shin, J S , Youn, J K
    Yonsei medical journal v.34 no.3 ,pp. 258 - 265 , 1993 , 0513-5796 ,

    초록

    We have investigated in vitro proliferative responses of peripheral blood mononuclear cells and productions of interferon-gamma and soluble interleukin-2 receptors by these cells from 6 patients with chronic active hepatitis B immediately before and 24 hours after a single intravenous injection of 100 mg of polyadenylic.polyuridylic acid. Cell proliferations were assessed by the technique of tritiated-thymidine incorporation and productions of interferon-gamma and soluble interleukin-2 receptors were measured by enzyme-linked immunosorbent assay. The administration of polyadenylic.polyuridylic acid to the patients has resulted in significant increases of in vitro proliferations of their peripheral blood mononuclear cells as well as productions of interferon-gamma by these cells. However, in vitro productions of soluble interleukin-2 receptors were not changed significantly. These results suggest that the enhanced cellular responses by polyadenylic.polyuridylic acid might be due to the increased sensitivity rather than the increased expression of cellular interleukin-2 receptor.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [국내논문]   Regional differences in the levels of biogenic amines and their metabolites in rat brain after tricyclic antidepressant treatments.  

    Chung, M Y , Kim, D G , Yoo, K J , Hong, S S
    Yonsei medical journal v.34 no.3 ,pp. 266 - 277 , 1993 , 0513-5796 ,

    초록

    Changes in the levels of biogenic amines in different brain regions and the cerebrospinal fluid in rats were measured after acute or chronic treatment with tricyclic antidepressants. After single or 3 weeks' treatment with imipramine or desipramine, blocks of tissues were obtained from seven regions of the brain (frontal cortex, corpus striatum, hippocampus, thalamus, hypothalamus, substantia nigra and cerebellum) immediately after collection of the cerebrospinal fluid (CSF) from the cisterna magna. The concentrations of biogenic amines and their metabolites (norepinephrine, epinephrine, dopamine, 5-hydroxytryptamine (5-HT), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA)) in brain tissues and the CSF were measured using the high performance liquid chromatography-electrochemical detection system (HPLC-ECD). Treatment with desipramine or imipramine caused major alterations in the concentrations of central norepinephrine or 5-HT and its metabolite, respectively. Brain regional responses were variable according to the kind of tricyclic antidepressants and the duration of treatment. It is noteworthy that chronic treatment with both desipramine and imipramine caused altered hippocampal concentrations of norepinephrine and/or 5-HT and its metabolites. Striatal DOPAC concentrations were also changed after acute or chronic treatment with both drugs. These results suggest that tricyclic antidepressants altered neurotransmission according to the brain region, and the hippocampal norepinephrine and 5-HT and/or the striatal dopamine may have a significant role for the expression of antidepressant action of tricyclic antidepressants.

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  10. [국내논문]   Effect of wheelchair ergometer training on spinal cord-injured paraplegics.  

    Yim, S Y , Cho, K J , Park, C I , Yoon, T S , Han, D Y , Kim, S K , Lee, H L
    Yonsei medical journal v.34 no.3 ,pp. 278 - 286 , 1993 , 0513-5796 ,

    초록

    The purpose of this study was to investigate the effect of wheelchair ergometer training on spinal cord-injured paraplegics. Eleven male paraplegics with a mean age of 30.9 years (range, 20 to 49 years) participated in the wheelchair ergometer training for the period of 5 weeks. The mean peak heart rate, the mean peak systolic blood pressure and the mean time required for 100m wheelchair propelling at resistance level 1 were significantly decreased at the end of 5 weeks of training as compared with those at pre-training. There was no statistically significant difference in pulmonary function test at pre- and post-training. The peak torque of shoulder flexor and the total work of shoulder flexor and extensor at 180 degrees/sec after training were increased more significantly than those prior to the training. In accordance with the findings as revealed above, it is deemed that the endurance and strength of the upper body and the cardiac fitness for spinal cord-injured paraplegics may be improved by the wheelchair ergometer exercise.

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