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저널/프로시딩 상세정보

권호별목차 / 소장처보기

H : 소장처정보

T : 목차정보

大韓皮膚科學會誌 = Korean journal of dermatology 31건

  1. [국내논문]   Korean Acne Grading System  

    Sung, Kyung Jeh , Rho, Young Suck , Choi, Eung Ho , Oh, Jeong Joon , Lee, Joo Heung , Kim, Seonwoo , Kim, Nack In
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1241 - 1247 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: A good acne grading system should reflect epidemiological and clinical features of a particular patient group. Current Korean acne grading systems are mostly based on the skin colors, epidemiology, and clinical features of Western countries, which make them less than being ideal for Korean acne patients. OBJECTIVE: We tried to devise an acne grading system based on clinical and epidemiological characteristics of Korean acne patients. This system is intended for use in primary care setting as well as in research purposes. METHODS: In the formulation of a new acne grading system, a panel of 5 dermatologists from 5 referral centers took into account the degree of complexity of the system, criteria for severity as well as skin colors through the review of clinical photographs of 250 acne patients. The new grading system then underwent inter-rater and intra-rater discrepancy assessment and simulation with 149 patient photos to find out an optimal epidemiological representation. RESULTS: We developed 6-scale grading system with both standard pictures and ranges of number of lesions as criteria. Intra-rater and inter-rater reproducibility turned out to be moderate to strong, suggesting clear instruction and easy performance. Simulation with 4 different models yielded best parameter ranges for the optimal criteria. CONCLUSIONS: With the feedback from the large-scale field applications, this new acne grading system will serve as a multipurpose acne grading system for Korean patients.

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  2. [국내논문]   Pruritus Associated with Psoriasis  

    Kim, Kyoung Jin , Choi, Hye Jin , Choi, Jung Chul , Choi, Jee Ho
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1248 - 1254 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: Pruritus has been reported to be a common symptom of many psoriatic patients, although the significance of this complaint has often been overlooked by dermatologists. OBJECTIVES: This study was aimed to explore the prevalence and various related clinical characteristics of pruritus associated with psoriasis in Korean patients. METHODS: Questionnaire data from 131 psoriatic patients were analyzed and psoriasis severity was determined by PASI score evaluation. RESULTS: Pruritus was a symptom of psoriasis in 83% of patients. It involved usually on the areas of active psoriatic lesion and appeared mainly at night. The severity and extent of psoriasis in pruritic patients were significantly (p

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  3. [국내논문]   The Study of Post-adolescent Acne in Nurses  

    Jeong, Eugene , Park, Hyun Jeong , Lee, Jun Young , Cho, Baik Kee
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1255 - 1262 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: Acne is usually considered a disorder of adolescence, and a number of studies have examined the prevalence of this condition in the adolescent population. However, prevalence of acnes in patients over the age of 25 years has significantly increased. There are relatively few data on the prevalence of acne in the adult population, especially in Korea. Also, although many researches have been conducted into the etiology of this disease, much substantial myth still abounds with the treatment and cause of this condition. OBJECTIVE: This study was carried out to investigate the prevalence of acne in adult women, and to compare adolescent acne with post-adolescent acne in nurses. METHODS: We analyzed the answers from 504 nurses, who work in the St. Mary's Hospital, to questions about the acne. RESULTS: 1. Prevalence of post-adolescent acne was 36% in nurses of above the age of 25. Their mean age of onset of acne was 17.4 years. 2. The forehead and cheeks were the most common predilection sites in both groups. However, the jaw and perioral area were more common in the post-adolescent group than the adolescent group (p

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  4. [국내논문]   Clinical and Histopathological Analysis of Infantile Hemangiomas  

    Chung, Hye Jin , Chung, Kee Yang
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1263 - 1270 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: Infantile hemangiomas (IH) are the most common tumor of childhood. However, accurate diagnosis of hemangiomas and vascular malformations remains a challenge for physicians because of confusing terminology, lack of knowledge regarding their biological and clinical behavior, and poorly understood diagnostic criteria. OBJECTIVES: The purpose of this study was to analyze the clinical and histopathologic findings of infantile hemangiomas in Korean patients. METHODS: Two hundred and fifty one cases of infantile hemangiomas were reviewed retrospectively. We analyzed the patients in terms of their clinical features and histopathological features. RESULTS AND CONCLUSIONS: 1. Hemangiomas were observed predominantly in females with the sex ratio of 1:2.4. Head and neck were the most commonly involved sites and 14 cases showed family history. 2. IH was evident at birth in 42.6% of the patients. The onset of the proliferating phase was pronounced during the first 1 to 3 months of life, followed by the involuting phase. IH that resolved after 6 years of age were more likely to leave a residual scar or telangiectasia than those which resolved before the age of 6. 3. Complications included ulcerations, erosions, secondary infection, bleeding tendency, ocular obstruction, nasal obstruction, respiratory difficulty and Kasabach-Merritt syndrome. 4. In H & E stains, hemangioma in the proliferating phase showed plump endothelial cells and increased endothelial cell activity with the formation of syncytial masses. The specimens in the involuting phase showed flattened endothelial cells and dilated lumens wheareas involuted lesions showed areas of fibrofatty infiltration.

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  5. [국내논문]   Correction of International Classification of Disease, for Effective Management of Dermatologic Disease  

    Kim, Hyun Woong , Seo, Young Joon , Park, Jang Kyu , Lee, Jeung Hoon , Chinn, Yong Woo
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1271 - 1276 , 2004 , 0494-4739 ,

    초록

    In our country the ICD-10(International classification of disease) is used to classify disease. But it has many problems in classifying and managing statistics in the field of dermatology. For instance, there are many diseases that are not included in the ICD-10, and the classification is not organized. Also, in many cases the classification of ICD-10 has problems in computerizing. Even though we need a classification overcoming these problems, National health insurance corporation is using the ICD-10. In this study, we corrected the problems of the ICD-10 to make an improved ICD-10 to use in dermatologic fields. To do this, we had to search all the dermatologic disease code contained in the ICD-10, and find all the disease listed in the book of domestic and foreign. We had to compare and analyse these. Subsequently, we add the diseases that are not contained in the ICD-10, organized the classification and improved the dermatologic disease code of ICD-10. This classification would be useful for the management of disease in the dermatologic field.

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  6. [국내논문]   Correlation between Androgenetic Alopecia and Lipid Parameters for Risk Factors of Coronary Artery Disease  

    Choe, Seong Wook , Yoon, Yang Hyun , Ro, Byung In
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1277 - 1284 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: The association of androgenetic alopecia and coronary artery disease has not been well documented although many studies have tried to reveal this association. This relationship is still a controversial issue. OBJECTIVES: The aim of this study is to investigate the association between the androgenetic alopecia and lipid parameters for risk factors of coronary artery disease. METHODS: The subjects of this study were 102 patients with androgenetic alopecia who had visited the Department of Dermatology, Pil-dong Hospital, College of medicine, Chung-Ang University during 2 years (from January 2000 to December 2001). The subjects of control group were 40 male individuals who had no androgenetic alopecia, no risk factor of coronary artery disease and no coronary artery disease. RESULTS: 1. There were significant differences in the serum total lipid, phospholipid, triglyceride between the patients and the control group. But there were no significant differences in serum LDL-cholesterol, HDL-cholesterol, and total cholesterol between the two groups. 2. There were significant differences in the serum total lipid, phospholipid, triglyceride between frontal baldness patients and the control group (p

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  7. [국내논문]   Clinical Study of Dermatologic Disorders in Patients with Breast Cancer  

    Kim, Duk Han , Lee, Jeong Deuk , Cho, Sang Hyun , Oh, Se Jeong
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1285 - 1293 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: In Korea, breast cancer is the most common cancer in female and its incidence is increasing recently. Moreover, breast cancer is the most common cutaneous metastasis in female. However, dermatologic disorders manifested in patients with breast cancer have not been investigated yet. OBJECTIVES: Our purpose was to study the clinical characteristics of dermatologic disorders in patients with breast cancer. METHODS: A clinical observation and review of medical records were made by analyzing 359 cases of breast cancer who visited Our Lady of Mercy hospital from 1994 to 2003. Among them, 91 cases of the patients with breast cancer showed dermatologic disorders. Their photographs of cutaneous findings and histologic specimens were reviewed by more than 2 dermatologists. RESULTS & CONCLUSIONS: 1. The mean age at the diagnosis of breast cancer was 48.74+/-11.28 years old. 2. The stages of patients with breast cancer were as follows: stage 0 (4 cases), stage 1 (48 cases), stage 2 (196 cases), stage 3 (94 cases), stage 4 (2 cases), and others (15 cases). 3. The treatments of patients with breast cancer were as follows: surgery (358 cases), radiation therapy (115 cases), chemotherapy (256 cases), combination of chemotherapy and radiation therapy (82 cases), and others (9 cases). 4. The numbers of patients developing cutaneous infections among the patients with breast cancer were as follows: bacterial infection (18 cases), fungal infection (18 cases), and viral infection (14 cases). 5. The numbers of patients developing pruritus and eczema among the patients with breast cancer were as follows: contact dermatitis (7 cases), seborrheic dermatitis (3 cases), neurodermatitis (2 cases), and others (9 cases). 6. The numbers of patients developing treatment-associated dermatologic disorders among the patients with breast cancer were as follows: urticaria (11 cases), radiodermatitis (8 cases), drug eruption (6 cases), and lymphedema (1 case). 7. The number of patients developing skin metastasis among the patients with breast cancer was 10 cases. 8. The numbers of patients developing other dermatologic disorders among the patients with breast cancer were as follows: psoriasis (4 cases), erythema multiforme (2 cases), and others (16 cases). 9. The numbers of patients developing postoperative dermatologic complications were as follows: seroma (28 cases), arm swelling and lymphedema (9 cases), wound infection (6 cases), and others (5 cases).

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  8. [국내논문]   A Study of the Effect of Tacrolimus Ointment on the Staphylococcal Colonization in Atopic Dermatitis Patients  

    Lee, Bo Hyun , Park, Chun Wook , Lee, Cheol Heon
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1294 - 1303 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: It is well known that topical tacrolimus is safe and effective on the treatment of atopic dermatitis (AD) patients. Tacrolimus is a primarily immunosuppressive agent without antistaphylococcal effect. Thus the colonization of staphylococcus aureus (S. aureus), on the skin of patients treated with this agent, might be increased. OBJECT: The purpose of this study is to know the effect of tacrolimus on S. aureus colonization of patients with AD and to compare the result with clinical severity and skin barrier function. METHOD: We enrolled 65 patients with moderate to severe AD. They were treated with 0.03% tacrolimus ointment twice daily for 4 weeks. Clinical severity was assessed by the eczema area and severity index (EASI). S. aureus colonization was measured by tape method. Skin barrier function was checked by measuring the transepidermal water loss (TEWL). Evaluations were performed at week 0 (baseline), 1st, 2nd and 4th. The results were compared and the statistical analysis was performed. RESULTS: S. aureus colonization was significantly decreased with tacrolimus treatment at week 1st as compared with baseline. But there were no differences among week 1st, 2nd and 4th. EASI and TEWL showed a decreasing tendency in a time dependent fashion. The correlations between each data were variable. CONCLUSION: Topical application of tacrolimus ointment reduce the colonization of S. aureus on the skin of patients with AD. Moreover, the severity of AD and skin barrier function were improved with treatment. However it is not sure the effect of tacrolimus as a long-term maintenance therapy based on this data, because this is a short term study. In future assessment of topical agents and S. aureus colonization, it will be important to make a study by the comparative method and for a long term period.

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  9. [국내논문]   The Changes of Epidermal Lipid and Calcium in the Lesion of Skin Tumor and Non-tumor of Hairless Mice Induced by Vinyl Carbamate Epoxide and TPA  

    Ahn, Sung Ku , Bak, Hana , Chun, Seung Hyun , Jeon, Soo Young , Choi, Eung Ho , Lee, Sang Joo , Lee, Seung Hun
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1304 - 1312 , 2004 , 0494-4739 ,

    초록

    BACKGROUND: Chemically induced epidermal carcinogenesis is usually divided into two stages, the initiation and promotion. The initiation involves conversion of some epidermal cells into latent neoplastic cells and the promotion is proliferation of the transformed cells. Ethyl carbamate (EC) has been identified at low microgram quantities in various fermented beverages, distilled products and tobacco smoke. It has been known as a initiator of tumor. Oxidation of the ethyl group of EC is followed by dehydration to yield the carcinogen vinyl carbamate (VC). This is further oxidized to vinyl carbamate epoxide (VCO). VC and VCO proved to be much more carcinogenic than EC. OBJECT: This study is attemped to investigate the skin tumor and non-skin tumor in hairless mice induced by application of 12-0-tetradecanoyl-phorbol-13-acetate (TPA) on the skin initiated with VCO and its relationship with calcium gradient and epidermal lipid. METHODS: In this experiment, the tumor induction was performed by painting the mouse skin once a week for five weeks with VCO solution, and then 12-0-tetradecanoyl-phobol-13-acetate (TPA) was treated in the same manner twice a week for 40 weeks. We biopsied the skin at 5, 10, 25, 30, 35 and 40 weeks and stained the specimens with hematoxylin-eosin, Ru04 postfixation and ion capture cytochemistry for calcium staining. RESULTS: The results are summerized as follows 1. Cellular proliferation, hyperkeratosis and dysplasia of the epidermis were more prominent in skin tumors than non-skin tumors. Papillomas were developed at 8 weeks after application of VCO- TPA but not TPA alone. The occurrence of keratoacanthoma and squamous cell carcinoma was 33 and 39 weeks, respectively. 2. Calcium gradient was distorted in the only TPA treatment group but normal in the control group. Calcium deposition was increased through all layers of epidermis and the calcium gradient was disappeared in the epidermis of tumors in the VCO-TPA treatment group. These findings were similar to papilloma, keratoacanthoma and squamous cell carcinoma. 3. Fragmented, incomplete lipid bilayer formation, dilated intercellular spaces and multiple lacunar domains were prominent in the VCO-TPA and TPA treatment groups but not in the control group. The VCO-TPA treatment group has shown more epidermal lipid damage than that of the only TPA treatment group. 4. Diploid DNA histogram patterns were observed in all the control and TPA treatment groups. But aneuploidy was observed in 1 of 3 keratoacanthomas and 3 of 3 squamous cell carcinomas. CONCLUSION: From the above results, it is concluded that various skin tumors, such as papilloma, keratoacanthoma and squamous cell carcinoma or non-skin tumor were produced by VCO. Skin tumors showed various, distinctive light microscopic or electron microscopic changes compared to the non-skin tumor. It is thought that intercellular lipid change and calcium gradient disappearance in the epidermis have an important role in the carcinogenesis.

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  10. [국내논문]   A Case of Idiopathic Calcinosis Universalis  

    Kim, Byoung Dae , Bang, Dongsik
    大韓皮膚科學會誌 = Korean journal of dermatology v.42 no.10 ,pp. 1313 - 1316 , 2004 , 0494-4739 ,

    초록

    Calcinosis cutis results from deposits of calcium and phosphorus in the skin. Calcinosis cutis may be divided into four major categories: dystrophic, metastatic, idiopathic and iatrogenic. A 19-year-old female presented with multiple brown or skin-colored, stony hard plaques on the face, trunk, arm and thigh for 18 months. She did not have any familial and medical history. None of the laboratory findings, including serum calcium, phosphate and autoantibodies for connective tissue disease, was significant. X-ray examination of bones evidenced multiple reticulated heterotrophic calcifications and whole body bone scan evidenced increased radiotracer uptake according to cutaneous or subcutaneous tissue. This case is compatible with idiopathic calcinosis universalis. Treatment with diltiazem was started.

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