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저널/프로시딩 상세정보

권호별목차 / 소장처보기

H : 소장처정보

T : 목차정보

大韓皮膚科學會誌 = Korean journal of dermatology 29건

  1. [국내논문]   Endovenous Laser Treatment of Varicose Veins: Long-Term Results  

    Song, Ki Hoon , Kwon, Oh Eon , Sim, Seung Joo , Kim, Ki Ho
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 297 - 304 , 2005 , 0494-4739 ,

    초록

    PURPOSE: It is necessary to eliminate the highest point of reflux originating at the saphenofemoral junction (SFJ) and the great saphenous vein (GSV) to treat varicose veins. Minimal invasive alternatives in the treatment of varicose veins due to the SFJ and GSV incompetence have been tried over the years, resulting in various degrees of success depending on the method. Recently, endovenous laser occlusion using a diode laser has been introduced, with initial successful clinical reports. The present study was conducted to evaluate long-term follow-up results of endovenous laser treatment for closing the incompetent GSV at its junction with the femoral vein. METHOD: Forty limbs (thirty one patients) with reflux at the SFJ into the GSV were treated with 810nm or 940nm diode laser energy, administered endovenously through a bare-tipped laser fiber (600micrometer). The parameters were 12~15 W in a continuous mode, with a pulse of laser energy every second. A duplex doppler ultrasound (DDUS) was used to mark the location of the GSV from the knee to the SFJ. Vein access was achieved by using either the stab wound Mueller hook approach or ultrasound-guided needle puncture. Exact placement of the fiber was determined by direct observation of the aiming beam through the skin or ultrasound confirmation. Where necessary, a standard ambulatory phlebectomy was performed to remove remaining varicosities. Clinical and duplex evaluation was carried out at regular intervals (1, 3, 6, 12 months) following the initial treatment. RESULTS: Successful occlusion of the GSV, defined as absence of flow on the DDUS, was noted in 39 of 40 GSV (97.5%) during the last visit. Recanalization of GSV occurred in two limbs, 3 and 6 months after treatment. The GSV junction of 7 limbs had remained closed for 2 years. Side effects were minimal, with 21 limbs showing significant purpura, 6 limbs developing palpable fibrous cord and 4 limbs showing transient hyperpigmentation within less than 2 weeks to one month after treatment. CONCLUSION: Long-term results obtained from treatment of 40 limbs with endovenous laser treatment demonstrate a recurrence rate of less than 6% after 29 months of follow-up. These results are comparable or superior to those available for treatment of GSV reflux, including surgery, US-guided sclerotherapy, and radiofrequency ablation. Endovenous laser treatment appears to offer the benefit of lower rates of complication and the avoidance of general anesthesia.

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  2. [국내논문]   Local Flaps for Reconstruction of Nasal Defects  

    Kim, Yong Ju , Song, Hae Jun , Kye, Young Chul , Oh, Chil Hwan , Kim, Soo Nam , Yu, Dong Soo
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 305 - 311 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: The skin over the nose is not relatively less mobile for primary closure of nasal defects. In addition to skin grafts and secondary intention healing, there are various local flap techniques available for the reconstruction of nasal defects. OBJECTIVE: The aim of this study was to assess the effectiveness and the cosmetic consequences of various local flap techniques in reconstructing nasal defects. METHODS: Between December 2002 and April 2004, 18 patients were treated with a local flap technique for the reconstruction of a nasal skin defect following Mohs micrographic surgery. The post-operative result of each case was rated with serial clinical photographs and medical records by two independent physicians. RESULTS: The nasal skin defects were reconstructed with various local flaps, such as the nasolabial interpolation flap, bilobed flap, glabellar flap, median forehead flap, and subcutaneous island pedicle flap. The cosmetic and functional results of the nasal reconstructions were judged to be generally satisfactory, excluding a trapdoor deformity in one patient, and eyebrow distortion and cancer recurrence in another patient. The cosmetic results of the cases reconstructed with a subcutaneous island pedicle flap were favorable in color and texture of the flaps, and incision scar formation, compared to the other techniques used. CONCLUSION: There are various local flap techniques which can be used in the reconstruction of nasal defects, and each of them has its own merits and drawbacks. The reconstructive plan should be customized to the patient considering not only the size, depth and location of the defect but also the medical history of the patient, the patients expectations, and the surgeons experience. Reconstruction with a subcutaneous island pedicle flap has been found to be one of the most effective methods, and allows the surgeon to spend a relatively short time in reconstructing defects of the upper and lower part of the nose. Furthermore, it has many advantages over the skin graft and other local flap techniques, especially with the aesthetic result.

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  3. [국내논문]   Efficacy of 0.1% Tacrolimus Ointment in Korean Patients with Atopic Dermatitis  

    Kim, Hye One , Park, Chun Wook , Lee, Cheol Heon , Lee, Joung Ok
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 312 - 318 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Tacrolimus (FK 506) ointment is a recently developed topical immunomodulator, and preliminary studies suggest that topical application of tacrolimus is effective in the treatment of atopic dermatitis. OBJECTIVE: Our purpose was to evaluate the efficacy and safety of 0.1% tacrolimus ointment for the treatment of moderate to severe atopic dermatitis (AD) in Korea. METHOD/Patients: A total of 57 patients, 2 to 49 years of age, with moderate to severe AD applied 0.1% tacrolimus ointment twice daily for up to 4 weeks. The mean age of patients was 16.7 years. One-third of the patients had severe atopic dermatitis at baseline. Efficacy was evaluated by the Eczema Area and Severity Index (EASI) score. Other evaluations were based on the physician's and patient's global evaluation of clinical response. RESULT: Significantly more patients (p

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  4. [국내논문]   A Clinical Study of Androgenetic Alopecia (V)  

    Kim, Ji Eun , Ahn, Ji Young , Ro, Byung In
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 319 - 324 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Androgenetic alopecia is characterized by local and gradual transformations of terminal scalp hair to vellus hair, which has a shorter and thinner shaft. The proportion of patients with androgenetic alopecia, among the total number of patients with alopecia, seems to be gradually increasing. OBJECTIVE: The purpose of this study was to evaluate the family history, and clinical and endocrine status of patients with androgenetic alopecia. METHOD: 796 patients with androgenetic alopecia were assessed at the Alopecia Clinic, Department of Dermatology, College of Medicine, Chung-Ang University Hospital over a 3 year period (from January 2001 to December 2003). RESULTS: The following results were obtained: 1) There were found to be 1.7 more male patients (498) than female patients (298). They were also found to be mostly in their twenties (male 253; 50.8%, female 90; 30.2%). Previously, male to female ratio was 3.46: 1, but was now found to be 1.7: 1. 2) In the 498 male patients, Norwood class II was dominant (130 patients; 26.2%). In the 298 female patients, Ludwig class I was superior (204 patients; 68.5%). 3) 321 patients (64.5%) of 498 male patients and 177 (59.4%) of 298 female patients hada family history of androgenetic alopecia. 4) The most common accompanying disorder was seborrheic dermatitis (male 287; 73.0%, female 137; 64.6%). 5) Serum testosterone levels were increased in 84 (16.9%) of 498 male patients and 44 (14.8%) of 298 female patients. CONCLUSION: Most of these results are compatible with our previous study carried out in 1995. But, female androgenetic alopecia patients are nowadays increasing in number, therefore, the ratio of male to female is markedly different.

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  5. [국내논문]   Comparision of Effectiveness of Formic Acid and Liquid Nitrogen in the Treatment of Recalcitrant Warts  

    Yoon, Sun Young , Kang, Hoon , Lee, Jeong Deuk , Cho, Sang Hyun
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 325 - 330 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Liquid nitrogen (LN2) has been widely used in the treatment of warts. However, formic acid (FA), the keratolytic agent, has recently been introduced for the treatment of recalcitrant warts, such as palmoplantar or periungual warts. The efficacy of treatment varies depending on the location, size, number and type of wart, as well as the age and co-operation of the patient. OBJECTIVE: The aim of this study was to evaluate the efficacy and safety of FA and LN2 therapy for the treatment of warts. METHODS: Twenty-four patients with a total of 101 warts were treated with FA, and fifty-three patients with 248 warts were treated with LN2. In the FA-treated group, 85% FA was applied to the warts 2 to 7 times using a stick, according to the degree of response. In the LN2-treated group, LN2 was applied with the sustained 10-s freeze technique using a cotton tip. Treatment with FA was administered weekly, whereas treatment with LN2 (with 2 freeze thaw cycles) was administered in 2 week intervals. Treatment effectiveness was assessed when the complete clearance of warts had occurred or after 12 weeks of treatment. RESULTS: Complete clearance of warts occurred in 30.7% (31/101warts) of the FA-treated group, and 47.2% (119/248warts) of the LN2 treated group. Cryotherapy with LN2 was more effective than FA in the cure rate (p=0.001). In the FA-treated group, 11 patients reported adverse effects such as pain, stinging and erythema, however it was generally found to be tolerable and transient. In addition, 10 patients reported hyperpigmentation. In the LN2 group, 38 patients experienced mild- to-moderate vesicle formation and 9 patients reported hypopigmentation. CONCLUSION: This study shows that cryotherapy with LN2 is more effective than FA in the treatment of recalcitrant warts. However, LN2 causes a significantly greater morbidity in terms of pain and blistering. FA is an effective and safe alternative treatment, so can be considered for patients who are intolerable to pain.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  6. [국내논문]   Characteristics of Occupational Skin Diseases Compensated with the Industrial Accident Compensation Insurance from 1999 to 2003  

    Ahn, Yeon Soon , Kim, Duk Han , Lee, Jun Young , Kim, Hyoung Ok
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 331 - 341 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Of occupational diseases, although skin is a commonly affected site, skin diseases are rarely reported and have been poorly compensated in the past due to their relatively low morbidity rate. OBJECTIVE: The purpose of this study was to analyze the characteristics of occupational skin diseases compensated by the Industrial Accident Compensation Insurance which is managed by the Korea Labor Welfare Corporation (KLWC). METHOD: Using the KLWC database, we selected 216 cases of occupational skin diseases which had been compensated between 1 January 1999 and 31 December 2003. We analyzed the characteristics (sex, age, type of occupational disease, exposure material, type of industry and occupation, etc.) of occupational diseases, using data from the KLWC records and from cases that had been investigated by the Korea Occupational Safety and Health Agency (KOSHA). RESULTS: 216 cases were compensated by the KLWC, with men accounting for 76.4% (165 cases) of the cases. The most common age group was 50-59 years of age (n=73, 33.8%). The majority of diseases were contact dermatitis (116 cases, 53.7%), cellulitis (36 cases, 16.7%), leukoderma (11 cases, 5.7%), urticaria (9 cases, 4.2%) and scabies (7 cases, 3.2%). The causal hazardous agents of 147 cases were plants (72 cases, 49.0%), chemicals (32 cases, 21.8%), drugs (7 cases, 4.8%) and oils and greases (5 cases, 3.4%). The major types of industry were public administration and defence (91 cases, 42.1%), manufacturing (57 cases, 27.1%), other community, repair and personal service activities (13 cases, 6.0%), construction (12 cases, 5.6%) and business activities (11 cases, 5.1%). The type of occupation included elementary occupations (115 cases, 53.2%), craft and related trades workers (30 cases, 13.9%), plant and machine operators and assemblers (20 cases, 9.3%) and service workers (18 cases, 8.3%). CONCLUSION: From this study, we were able to elucidate the kind of occupational skin diseases and the characteristics of workers. Many of the compensated cases belonged to daily-paid workers in the public service, especially forestry care workers. The most commonly occurring disease was allergic contact dermatitis. This suggests that a management policy must be established to prevent occupational skin diseases occurring among workers in the above types of industry. Also, this study suggests that more research needs to be conducted to elucidate the relationship between exposure to hazardous agents and occupational skin diseases such as occupational skin cancers, leukoderma and trichloroethylene induced Stevens-Johnson Syndrome.

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  7. [국내논문]   Effects of Calcitonin Gene-Related Peptide on the Hair Growth in Human Hair Follicle Organ Culture  

    Oh, Tak Heon , Lee, Eun Young , Lee, Sanghoon , Lee, Won Soo
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 342 - 351 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: It has recently been reported that the peripheral nervous system has an important role in the hair growth and hair cycle change, which is mediated by neuropeptides. Furthermore, the expression of various growth factors and apoptosis-related molecules are important in the hair growth and hair cycle change. Therefore, it is important that the relationship between the influence of neuropeptides and expression of various factors that regulate hair growth is analysed. OBJECTIVE: The purpose of this study was to investigate the relationship between influence of neuropeptides and expression of various hair growth-related factors in the hair follicle, after pre- treatment of cultured hair follicles and dermal papilla cells with a calcitonin gene-related peptide (CGRP). METHOD: Normal human scalp samples were obtained, and anagen hair follicles and dermal papilla cells were isolated and cultured in Dulbeco?s Modified Eagle's Medium (DMEM) with several combinations of supplements, in an air incubator with an atmosphere of 5% CO2/95%. The culture plates were divided into two groups: a control group (DMEM only) and a CGRP group(10-7M CGRP dissolved in DMEM). The results were then evaluated by measuring the linear hair growth and hair follicle morphology under a light microscope. In addition, after pre-treatment of cultured hair follicles and dermal papilla cells with CGRP, we examined changes of expression of hair growth factors (FGF-7, IGF-1, VEGF), hair growth-inhibitory factors (IL-1alpha, IL-1beta) and apoptosis-related molecules (p53, caspase-3). RESULTS: The following results were obtained: 1. The CGRP did not have statistically significant effect on the rate of linear hair growth in cultured hair follicles. However, it shortened the anagen stage of the hair cycle. 2. In hair follicles, the expression of IL-1beta, a hair growth inhibitory factor, was increased in the CGRP group, compared to the control. The expression of caspase-3, an apoptosis-related molecule, was also found to be higher than the control. In dermal papilla cells, no change in morphology, expression of hair growth factors or apoptosis-related molecules were found. However the expression of IL-1beta was increased, compared to the control. CONCLUSION: From these results, we can conclude that CGRP has a growth-inhibitory effect, especially in shortening the duration of the anagen phase without affecting the linear hair growth rate. CGRP also shows a hair growth-inhibitory effect at the molecular level in hair follicles and dermal papilla cells.

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  8. [국내논문]   Assessment of the Quality of Life in Patients with Varicose Veins for Evaluation of Treatment Effect  

    Jang, Bong Seok , Chin, Hyun Woo , Lee, Chea Wook , Jo, Ju Hyun , Kim, Moon Bum , Jang, Ho Sun , Kwon, Kyung Sool , Oh, Chang Keun
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 352 - 358 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Varicose veins are the most common venous condition of the lower extremities. Treatment for varicose veins varies from surgery to minimally invasive techniques such as radiofrequency endovenous occlusion (RFEO), ambulatory phlebectomy (AP), sclerotherapy and endovenous laser treatment (EVLT). However, there is no method to assess the quality of life (QOL) of patients with varicose veins and the effect of treatment on the QOL. OBJECTIVE: The purpose of this study was to assess the QOL of patients with varicose veins and to evaluate the effect of treatment on the QOL. METHOD: A total of 72 patients with varicose veins were interviewed with the Aberdeen varicose vein questionnaire (AVVQ), was asked 25 questions relating to the symptoms and concerns of their condition. Follow-up was done with questionnaires again, 8 weeks after treatment. RESULTS: The results obtained are summarized as follows: 1. Of the 32 patients the distribution of age was 40-49 years of age (37.5%), followed by 50-59 years of age (27.8%) and 30-39 years of age (19.4%). The mean age was 47.7 years old. 2. 30 patients (41.8%) had suffered with varicose veins for less than 5 years, and 24 patients (33.3%) for 6-10 years. 3. According to the CEAP classification, the most common type of varicose vein was the C1AEPAS (31.9%). 4. Treatment method of varicose veins were sclerotherapy in 60 patients (83.3%), AP in 10 patients (13.9%), and RFEO in 2 patients (2.8%). 5. AVVQ scores correlated with symptoms and concern scores, and also with the clinical grade. 6. After treatment, AVVQ scores demonstrated a highly significant increase. CONCLUSION: This study confirms that varicose veins have a significant impact on the overall QOL, and that QOL shows a significant improvement after treatment. Therefore, assessment of QOL in patients with varicose veins can be a valid measure for the evaluation of treatment effect.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [국내논문]   Clinicopathologic Study of Cutaneous Horns  

    Kim, You Jeong , Oh, Shin Taek , Kang, Hoon , Park, Chul Jong , Park, Young Min , Cho, Sang Hyun , Lee, Jun Young , Kim, Jin Woo , Kim, Si Yong , Lee, Jeong Deuk
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 359 - 365 , 2005 , 0494-4739 ,

    초록

    BACKGROUND: Cutaneous horn is a morphological designation for a protuberant mass of keratin that resembles the horn of an animal. This reaction pattern is often seen in the background of a variety of primary diseases such as the benign, premalignant, or malignant tumors, and can mask numerous conditions. OBJECTIVE: The purpose of this study was to investigate clinical and histopathological features of cutaneous horns, especially focusing on the underlying diseases. METHOD: We reviewed the medical records and biopsy specimens of 72 cases of cutaneous horns which were diagnosed between January 1991 and July 2004 in 8 hospitals under the charge of Catholic Medical Centers. RESULTS: We compiled clinical data and histologic information on the 72 cases of cutaneous horns as follows: 1. The mean age at diagnosis was 54.3 years, and 69.7% of the patients were over 50 years old. Cutaneous horn developed predominantly in female, as the sex ratio of 1: 1.2. 2. The disease duration did not exceed 1 year in 55.5% of patients. Most patients were asymptomatic, but 11.6% and 15.9% of patients complained of pruritus and pain, respectively. The lesions were usually solitary. 3. Cutaneous horns occurred on the face and neck, trunk, and extremities in 73.6%, 12.5%, and 13.9% of cases respectively, and cheeks, neck, scalp and hands were found to be commonly involved. 4. Histopathologically, 79.2% of cutaneous horns were associated with benign specimens at the base pathology, 15.3% were premalignant, and 5.6% were caused by malignant skin disease. With the benign pathological cases, common lesion were viral warts, and in premalignant cases, actinic keratosis. The malignant lesions were found to consist of squamous cell carcinoma and basal cell carcinoma. 5. Four main features were associated with premalignant or malignant histopathological changes at the base of the cutaneous horns. These were older age, female sex, shorter duration of illness, accompanied pain. CONCLUSION: Cutaneous horn is the term given to a protrusion of keratinized material on the skin, and is often found to arise on sun-exposed skin in elderly men. It may be derived from a benign, premalignant, or malignant lesion. Benign lesions were found to occupy most of the base pathology in Korea. However, because of the possibility of masking malignant lesions, sufficient specimens from the base of lesions should be carefully obtained.

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  10. [국내논문]   A Case of Fungal Folliculitis Clinically Mimicking Lupus Miliaris Disseminatus Faciei  

    Um, Sung Hee , Kang, Nam Kyu , Ahn, Kyu Joong , Oh, Chee Won
    大韓皮膚科學會誌 = Korean journal of dermatology v.43 no.3 ,pp. 366 - 370 , 2005 , 0494-4739 ,

    초록

    Dermatophytes generally cause infection of the stratum corneum and superficial layers of skin. They are, therefore, found less frequently in the rete layer and do not ordinarily penetrate deeper than the basal cell layer. Nevertheless, under special circumstances such as the pressure generated during trauma or long term topical steroid application, the fungus elements of some dermatophytes will be forced into the dermis where they instigate a chronic granulomatous reaction. We report a 43-year-old male who presented with multiple erythematous brown colored dome-shaped papules on both periorbital areas, which were clinically similar to lupus miliaris disseminatus faciei (LMDF). Histologic examination revealed follicular and perifollicular infiltration by inflammatory cells, and perifollicular granuloma. Trichophyton species were isolated from the fungus culture of the lesional tissue. The patient was treated with an antifungal agent, resulting in clearance of the skin lesions, and there was no recurrence of skin lesions during a 13-month follow-up period. We suggest that it is important to perform biopsies and cultures on periorbital papules which mimick LMDF, refractory to conventional therapy.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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