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Journal of pain and symptom management 365건

  1. [해외논문]   The Collusion Classification Grid: A Supervision and Research Tool   SCIE

    Stiefel, Friedrich
    Journal of pain and symptom management v.55 no.2 ,pp. e1 - e3 , 2018 , 0885-3924 ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  2. [해외논문]   Clinical Variety May Help Prevent Burnout After a Decade in Palliative Care   SCIE

    Koh, Mervyn , Hum, Allyn
    Journal of pain and symptom management v.55 no.2 ,pp. e3 - e5 , 2018 , 0885-3924 ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

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  3. [해외논문]   Editorial Board   SCIE


    Journal of pain and symptom management v.55 no.2 ,pp. A2 - A2 , 2018 , 0885-3924 ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   Table of Contents   SCIE


    Journal of pain and symptom management v.55 no.2 ,pp. A5 - A9 , 2018 , 0885-3924 ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  5. [해외논문]   Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain   SCIE

    Lichtman, Aron H. (Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA ) , Lux, Eberhard Albert (Faculty of Medicine, Witten/Herdecke University, Witten, Germany ) , McQuade, Robert (Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, New Jersey, USA ) , Rossetti, Sandro (Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, New Jersey, USA ) , Sanchez, Raymond (Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, New Jersey, USA ) , Sun, Wei (Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, New Jersey, USA ) , Wright, Stephen (GW Pharmaceuticals Ltd, Cambridge, UK ) , Kornyeyeva, Elena (Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, New Jersey, USA ) , Fallon, Marie T. (Edinburgh Cancer Research Centre, The University of Edinburgh, Edinburgh, UK)
    Journal of pain and symptom management v.55 no.2 ,pp. 179 - 188.e1 , 2018 , 0885-3924 ,

    초록

    Abstract Context Prior Phase 2/3 studies found that cannabinoids might provide adjunctive analgesia in advanced cancer patients with uncontrolled pain. Objectives To assess adjunctive nabiximols (Sativex ? ), an extract of Cannabis sativa containing two potentially therapeutic cannabinoids (Δ9-tetrahydrocannabinol [27 mg/mL] and cannabidiol [25 mg/mL]), in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy. Methods Phase 3, double-blind, randomized, placebo-controlled trial in patients with advanced cancer and average pain Numerical Rating Scale scores ≥4 and ≤8 despite optimized opioid therapy. Patients randomized to nabiximols ( n = 199) or placebo ( n = 198) self-titrated study medications over a two-week period, followed by a three-week treatment period at the titrated dose. Results Median percent improvements in average pain Numerical Rating Scale score from baseline to end of treatment in the nabiximols and placebo groups were 10.7% vs. 4.5% ( P = 0.0854) in the intention-to-treat population (primary variable) and 15.5% vs. 6.3% ( P = 0.0378) in the per-protocol population. Nabiximols was statistically superior to placebo on two of three quality-of-life instruments at Week 3 and on all three at Week 5. In exploratory post hoc analyses, U.S. patients, but not patients from the rest of the world, experienced significant benefits from nabiximols on multiple secondary endpoints. Possible contributing factors to differences in nabiximols efficacy include: 1) the U.S. participants received lower doses of opioids at baseline than the rest of the world and 2) the subgroups had different distribution of cancer pain types, which may have been related to differences in pathophysiology of pain. The safety profile of nabiximols was consistent with earlier studies. Conclusions Although not superior to placebo on the primary efficacy endpoint, nabiximols had benefits on multiple secondary endpoints, particularly in the U.S. patients. Nabiximols might have utility in patients with advanced cancer who receive a lower opioid dose, such as individuals with early intolerance to opioid therapy.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  6. [해외논문]   Which Physicians' Behaviors on Death Pronouncement Affect Family-Perceived Physician Compassion? A Randomized, Scripted, Video-Vignette Study  

    Mori, Masanori , Fujimori, Maiko , Hamano, Jun , Naito, Akemi S. , Morita, Tatsuya
    Journal of pain and symptom management v.55 no.2 ,pp. 189 - 197.e4 , 2018 , 0885-3924 ,

    초록

    Abstract Context Prior Phase 2/3 studies found that cannabinoids might provide adjunctive analgesia in advanced cancer patients with uncontrolled pain. Objectives To assess adjunctive nabiximols (Sativex ? ), an extract of Cannabis sativa containing two potentially therapeutic cannabinoids (Δ9-tetrahydrocannabinol [27 mg/mL] and cannabidiol [25 mg/mL]), in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy. Methods Phase 3, double-blind, randomized, placebo-controlled trial in patients with advanced cancer and average pain Numerical Rating Scale scores ≥4 and ≤8 despite optimized opioid therapy. Patients randomized to nabiximols ( n = 199) or placebo ( n = 198) self-titrated study medications over a two-week period, followed by a three-week treatment period at the titrated dose. Results Median percent improvements in average pain Numerical Rating Scale score from baseline to end of treatment in the nabiximols and placebo groups were 10.7% vs. 4.5% ( P = 0.0854) in the intention-to-treat population (primary variable) and 15.5% vs. 6.3% ( P = 0.0378) in the per-protocol population. Nabiximols was statistically superior to placebo on two of three quality-of-life instruments at Week 3 and on all three at Week 5. In exploratory post hoc analyses, U.S. patients, but not patients from the rest of the world, experienced significant benefits from nabiximols on multiple secondary endpoints. Possible contributing factors to differences in nabiximols efficacy include: 1) the U.S. participants received lower doses of opioids at baseline than the rest of the world and 2) the subgroups had different distribution of cancer pain types, which may have been related to differences in pathophysiology of pain. The safety profile of nabiximols was consistent with earlier studies. Conclusions Although not superior to placebo on the primary efficacy endpoint, nabiximols had benefits on multiple secondary endpoints, particularly in the U.S. patients. Nabiximols might have utility in patients with advanced cancer who receive a lower opioid dose, such as individuals with early intolerance to opioid therapy.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  7. [해외논문]   Which Physicians' Behaviors on Death Pronouncement Affect Family-Perceived Physician Compassion? A Randomized, Scripted, Video-Vignette Study   SCIE

    Mori, Masanori (Palliative Care Team, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan ) , Fujimori, Maiko (Office for Promotion of Support for Suicide Survivor, National Institute of Mental Health, National Center for Neurology and Psychiatry, Kodaira, Tokyo, Japan ) , Hamano, Jun (Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan ) , Naito, Akemi S. (Seirei Hospice, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan ) , Morita, Tatsuya (Division of Palliative and Supportive Care, Seirei Mikatahara General Hospital, Hamamatsu, Shizuoka, Japan)
    Journal of pain and symptom management v.55 no.2 ,pp. 189 - 197.e4 , 2018 , 0885-3924 ,

    초록

    Abstract Context Although the death of a loved one is a devastating family event, little is known about which behaviors positively affect families' perceptions on death pronouncements. Objectives The objective of this study was to evaluate the effect of a compassionate death pronouncement on participant-perceived physician compassion, trust in physicians, and emotions. Methods In this randomized, video-vignette study, 92 people (≥50 years) in Tokyo metropolitan area viewed two videos of death pronouncements by an on-call physician with or without compassion-enhanced behaviors, including five components: waiting until the families calm themselves down, explaining that the physician has received a sign-out about information of the patient's condition, performing examination respectfully, ascertaining the time of death with a wristwatch (vs. smartphone), and reassuring the families that the patient did not experience pain. Main outcomes were physician compassion score, trust in physician, and emotions. Results After viewing the video with compassion-enhanced behaviors compared with the video without them, participants assigned significantly lower compassion scores (reflecting higher physician compassion) (mean 26.2 vs. 36.4, F = 33.1, P F = 39.7, P F = 18.0, P F = 11.8, P = 0.001), fear (1.93 vs. 2.55, F = 15.8, P F = 19.4, P Conclusion To convey compassion on death pronouncement, we recommend that physicians initiate prompt examination, explain that the physician has received a sign-out, perform examination respectfully, ascertain the time of death with a wristwatch, and reassure the families that the patient did not experience pain.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  8. [해외논문]   Cranial Electrotherapy Stimulation for the Management of Depression, Anxiety, Sleep Disturbance, and Pain in Patients With Advanced Cancer: A Preliminary Study   SCIE

    Yennurajalingam, Sriram (Department of Palliative Care, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Kang, Duck-Hee (Center for Nursing Research, University of Texas School of Nursing, Houston, Texas, USA ) , Hwu, Wen-Jen (Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Padhye, Nikhil S. (Center for Nursing Research, University of Texas School of Nursing, Houston, Texas, USA ) , Masino, Charles (Department of Palliative Care, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Dibaj, Seyedeh S. (Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Liu, Diane D. (Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Williams, Janet L. (Department of Palliative Care, Rehabilitation, and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ) , Lu, Zhanni (Department of Palliative Care, Rehabilitation, and Integrative Medic) , Bruera, Eduardo
    Journal of pain and symptom management v.55 no.2 ,pp. 198 - 206 , 2018 , 0885-3924 ,

    초록

    Abstract Context Cranial electrotherapy stimulation (CES) is a safe modulation of brain activity for treating depression, anxiety, insomnia, and pain. However, there are no published studies in patients with advanced cancer (ACPs). Objectives The aim of the study was to determine the feasibility and preliminary efficacy of a four-week CES intervention on depression, anxiety, sleep disturbance, and pain scores. Concurrent salivary biomarker studies were conducted. Methods In this one group open label pre- and post-intervention study with a four-week CES intervention, ACPs with one or more of four moderate intensity (≥3/10) Edmonton Symptom Assessment Scale (ESAS) symptoms (depression, anxiety, sleep disturbance, and pain) were eligible. Adherence (0%–100%), satisfaction rates (0–10), and safety were assessed. ESAS, Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index, Brief Pain Inventory, and salivary levels (cortisol, alpha amylase, C-reactive protein, and interleukin-1β, and interleukin-6) were assessed from baseline to Week 4. Results Thirty-three of 36 patients (92%) completed the CES. Median (interquartile range) adherence CES use and satisfaction scores were 93% (89–100) and 10% (9–10), respectively, and the adherence criteria was met in the study. CES use was safe (no Grade 3 or higher adverse events). HADS anxiety ( P P = 0.024), ESAS anxiety ( P = 0.001), ESAS depression ( P = 0.025), Brief Pain Inventory pain ( P = 0.013), Pittsburgh Sleep Quality Index daytime dysfunction ( P = 0.002), and medication use ( P = 0.006) scores improved after four-week CES treatment. Conclusion In this preliminary study, we found that the use of CES was safe and feasible in ACP. The use of CES was associated with significant improvement of depression, anxiety, pain, and sleep scores. These findings support further studies of CES in ACP for symptom control.

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  9. [해외논문]   Development and Field Test of an Audit Tool and Tracer Methodology for Clinician Assessment of Quality in End-of-Life Care   SCIE

    Bookbinder, Marilyn (<i>Address correspondence to:</i>Marilyn Bookbinder, PhD, RN, FPCN, MJHS Institute for Innovation in Palliative Care, 39 Broadway, 3rd Floor, New York, NY 10006, USA.) , Hugodot, Amandine , Freeman, Katherine , Homel, Peter , Santiago, Elisabeth , Riggs, Alexa , Gavin, Maggie , Chu, Alice , Brady, Ellen , Lesage, Pauline , Portenoy, Russell K.
    Journal of pain and symptom management v.55 no.2 ,pp. 207 - 216.e2 , 2018 , 0885-3924 ,

    초록

    Abstract Context Quality improvement in end-of-life care generally acquires data from charts or caregivers. “Tracer” methodology, which assesses real-time information from multiple sources, may provide complementary information. Objectives The objective of this study was to develop a valid brief audit tool that can guide assessment and rate care when used in a clinician tracer to evaluate the quality of care for the dying patient. Methods To identify items for a brief audit tool, 248 items were created to evaluate overall quality, quality in specific content areas (e.g., symptom management), and specific practices. Collected into three instruments, these items were used to interview professional caregivers and evaluate the charts of hospitalized patients who died. Evidence that this information could be validly captured using a small number of items was obtained through factor analyses, canonical correlations, and group comparisons. A nurse manager field tested tracer methodology using candidate items to evaluate the care provided to other patients who died. Results The survey of 145 deaths provided chart data and data from 445 interviews (26 physicians, 108 nurses, 18 social workers, and nine chaplains). The analyses yielded evidence of construct validity for a small number of items, demonstrating significant correlations between these items and content areas identified as latent variables in factor analyses. Criterion validity was suggested by significant differences in the ratings on these items between the palliative care unit and other units. The field test evaluated 127 deaths, demonstrated the feasibility of tracer methodology, and informed reworking of the candidate items into the 14-item Tracer EoLC v1 . Conclusion The Tracer EoLC v1 can be used with tracer methodology to guide the assessment and rate the quality of end-of-life care.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

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  10. [해외논문]   Characteristics of Older Adults in Primary Care Who May Benefit From Primary Palliative Care in the U.S.   SCIE

    Dudley, Nancy (Department of Social & Behavioral Sciences, School of Nursing, University of California, San Francisco, California, USA ) , Ritchie, Christine S. (Division of Geriatrics, Department of Medicine, University of California, San Francisco, California, USA ) , Wallhagen, Margaret I. (Department of Physiological Nursing, School of Nursing, University of California, San Francisco, California, USA ) , Covinsky, Kenneth E. (San Francisco Veterans' Affair Medical Center, Geriatrics, Palliative & Extended Care, San Francisco, California, USA ) , Cooper, Bruce A. (Dean's Office, School of Nursing, University of California, San Francisco, California, USA ) , Patel, Kanan (Division of Geriatrics, Department of Medicine, University of California, San Francisco, California, USA ) , Stijacic Cenzer, Irena (Division of Geriatrics, Department of Medicine, University of California, San Francisco, California, USA ) , Chapman, Susan A. (Department of Social & Behavioral Sciences, School of Nursing, University of California, San Francisco, California, USA)
    Journal of pain and symptom management v.55 no.2 ,pp. 217 - 225 , 2018 , 0885-3924 ,

    초록

    Abstract Context Older adults with advanced illness and associated symptoms may benefit from primary palliative care, but limited data exist to identify older adults in U.S. primary care to benefit from this care. Objectives To describe U.S. primary care visits among adults aged 65 years and older with advanced illness. Methods Cross-sectional analysis of the National Ambulatory and Hospital Ambulatory Medical Care Surveys (2009–2011) was conducted using Chi-squared tests to compare visits without and with advanced illness with U.S. primary care defined by National Committee for Quality Assurance Palliative and End-of-Life Care Physician Performance Measurement Set International Classification of Diseases, Ninth Revision (ICD-9) codes for end-stage illness. Results Among visits by older adults to primary care, 7.9% visits were related to advanced illness. A higher proportion of advanced illness visits was among men vs. women (8.9% vs. 7.2%; P = 0.03) and adults aged 75 years and older, non-Hispanic whites (8.3%) and blacks (8.2%) vs. Hispanic (6.7%) and non-Hispanic other (2.5%) ( P = 0.02), dually eligible for Medicare and Medicaid, and from patient ZIP Codes with lower median household incomes (below $32,793). A higher percentage of visits with advanced illness conditions to primary care was chronic obstructive pulmonary disease, congestive heart failure, dementia, and cancer, and symptoms reported with these visits were mostly pain, depression, anxiety, fatigue, and insomnia. Conclusion In the U.S., approximately 8% primary care visits among older adults was related to advanced illness conditions. Advanced illness visits were most common among those most likely to be socioeconomically vulnerable and highlight the need to focus efforts for high-quality palliative care for these populations.

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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