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Heart : official journal of the British Cardiac So...Heart : official journal of the British Cardiac Society 14건

  1. [해외논문]   Heartbeat: Diabetes and heart failure   SCI SCIE

    Otto, Catherine M (Division of Cardiology, University of Washington, , Seattle, USA)
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 327 - 328 , 2017 , 1355-6037 ,

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  2. [해외논문]   Estimating cancer risk from invasive cardiac procedures in children   SCI SCIE

    Beausé (Inherited Cardiac Arrhythmia Program and Department of Paediatric Cardiology, Boston Children's Hospital, , Boston, Massachusetts, USA ) , jour Ladouceur, Virginie (Harvard Medical School, , Boston, Massachusetts, USA) , Lawler, Patrick R
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 329 - 330 , 2017 , 1355-6037 ,

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  3. [해외논문]   The long and unfinished journey of hyperglycaemia and heart failure research   SCI SCIE

    Rahimi, Kazem
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 331 - 332 , 2017 , 1355-6037 ,

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   Understanding sudden death risk in tetralogy of Fallot: from bedside to bench   SCI SCIE

    Seslar, Stephen ; Robinson, Melissa
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 333 - 334 , 2017 , 1355-6037 ,

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  5. [해외논문]   Graphics and statistics for cardiology: survival analysis   SCI SCIE

    May, Susanne (Department of Biostatistics, University of Washington, , Seattle, Washington, USA ) , McKnight, Barbara (Department of Biostatistics, University of Washington, , Seattle, Washington, USA)
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 335 - 340 , 2017 , 1355-6037 ,

    초록

    Reports of data in the medical literature frequently lack information needed to assess the validity and generalisability of study results. Some recommendations and standards for reporting have been developed over the last two decades, but few are available specifically for survival data. We provide recommendations for tabular and graphical representations of survival data. We argue that data and analytic software should be made available to promote reproducible research.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  6. [해외논문]   Survival adjusted cancer risks attributable to radiation exposure from cardiac catheterisations in children   SCI SCIE

    Harbron, Richard W (Newcastle University, Institute of Health and Society, Sir James Spence Institute, Royal Victoria Infirmary, , Newcastle-upon-Tyne, UK ) , Chapple, Claire-Louise (Regional Medical Physics Department, Freeman Hospital, Newcastle-upon-Tyne hospitals NHS trust, , Newcastle upon Tyne, UK ) , O'Sullivan, John J (Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, , Newcastle upon Tyne, UK ) , Best, Kate E (Newcastle University, Institute of Health and Society, Sir James Spence Institute, Royal Victoria Infirmary, , Newcastle-upon-Tyne, UK ) , Berrington de Gonzá (Radiation Epidemiology Unit, Division of Cancer Epidemiology and Genetics, NCI, , Bethesda, Maryland, USA ) , lez, Amy (Newcastle University, Institute of Health and Society, Sir James Spence Institute, Royal Victoria Infirmary, , Newcastle-upon-Tyne, UK) , Pearce, Mark S
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 341 - 346 , 2017 , 1355-6037 ,

    초록

    Objectives To estimate the risk of developing cancer in relation to the typical radiation doses received from a range of X-ray guided cardiac catheterisations in children, taking variable survival into account. Methods Radiation doses were estimated for 2749 procedures undertaken at five UK hospitals using Monte Carlo simulations. The lifetime attributable risk (LAR) of cancer incidence was estimated using models developed by the Biological Effects of Ionising Radiation committee, based on both normal life expectancy, and as a function of attained age, from 20 to 80 years, to take reduced life expectancy into account. Results The radiation-related risks from these procedures are dominated by lung and breast cancer (for females). Assuming normal life expectancy, central LAR estimates for cancer incidence, based on median doses, ranged from <1 in 2000 for atrial septal defect occlusions to as high as 1 in 150 for valve replacements. For a reduced life expectancy of 50 years, estimated risks are lower by a factor of around 7. For conditions with especially poor survival (age 20 years), such as hypoplastic left heart syndrome, estimated cancer risks attributable to radiation were <1 in 20 000. Conclusions Based on recent UK radiation dose levels, the risk of cancer following cardiac catheterisations is relatively low and strongly modified by survival and the type of procedure. The risk of breast cancer, especially following pulmonary artery angioplasty and valve replacements, is the greatest concern.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  7. [해외논문]   Proarrhythmic remodelling of the right ventricle in a porcine model of repaired tetralogy of Fallot   SCI SCIE

    Benoist, David (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Dubes, Virginie (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Roubertie, Francois (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Gilbert, Stephen H (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Charron, Sabine (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Constantin, Marion (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaque, Fondation Bordeaux Universitôéé, , Bordeaux, France ) , Elbes, Delphine (IHU LIRYC, L'Institut de Rythmologie et Modôélisation Cardiaqu) , Vieillot, Delphine , Quesson, Bruno , Cochet, Hubert , Haissaguerre, Michel , Rooryck, Caroline , Bordachar, Pierre , Thambo, Jean-Benoit , Bernus, Olivier
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 347 - 354 , 2017 , 1355-6037 ,

    초록

    Objective The growing adult population with surgically corrected tetralogy of Fallot (TOF) is at risk of arrhythmias and sudden cardiac death. We sought to investigate the contribution of right ventricular (RV) structural and electrophysiological remodelling to arrhythmia generation in a preclinical animal model of repaired TOF (rTOF). Methods and results Pigs mimicking rTOF underwent cardiac MRI functional characterisation and presented with pulmonary regurgitation, RV hypertrophy, dilatation and dysfunction compared with Sham-operated animals (Sham). Optical mapping of rTOF RV-perfused wedges revealed a significant prolongation of RV activation time with slower conduction velocities and regions of conduction slowing well beyond the surgical scar. A reduced protein expression and lateralisation of Connexin-43 were identified in rTOF RVs. A remodelling of extracellular matrix-related gene expression and an increase in collagen content that correlated with prolonged RV activation time were also found in these animals. RV action potential duration (APD) was prolonged in the epicardial anterior region at early and late repolarisation level, thus contributing to a greater APD heterogeneity and to altered transmural and anteroposterior APD gradients in rTOF RVs. APD remodelling involved changes in Kv4.3 and MiRP1 expression. Spontaneous arrhythmias were more frequent in rTOF wedges and more complex in the anterior than in the posterior RV. Conclusion Significant remodelling of RV conduction and repolarisation properties was found in pigs with rTOF. This remodelling generates a proarrhythmic substrate likely to facilitate re-entries and to contribute to sudden cardiac death in patients with rTOF.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [해외논문]   Contemporary risk estimates of three HbA1c variables in relation to heart failure following diagnosis of type 2 diabetes   SCI SCIE

    Skrtic, Stanko (AstraZeneca R&D, , Molndal, Sweden ) , Cabrera, Claudia (AstraZeneca R&D, , Molndal, Sweden ) , Olsson, Marita (AstraZeneca R&D, , Molndal, Sweden ) , Schnecke, Volker (AstraZeneca R&D, , Molndal, Sweden ) , Lind, Marcus (Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, , Gothenburg, Sweden)
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 353 - 358 , 2017 , 1355-6037 ,

    초록

    Background We evaluated the association between glycaemic control and the risk of heart failure (HF) in a contemporary cohort of persons followed after diagnosis of type 2 diabetes (T2D). Methods and results Persons with T2D diagnosed between 1998 and 2012 were retrieved from the Clinical Practice Research Data Link in the UK and followed from diagnosis until the event of HF, mortality, drop out from the database due to any other reason, or the end of the study on 1 July 2015. The association between each of three different haemoglobin A 1C (HbA 1c ) metrics and HF was estimated using adjusted proportional hazard models. In the overall cohort (n=94 332), the increased risk for HF per 1% (10 mmol/mol) increase in HbA 1c was 1.15 (95% CI 1.13 to 1.18) for updated mean HbA 1c , and 1.06 (1.04 to 1.07) and 1.06 (1.04 to 1.08) for baseline HbA 1c and updated latest HbA 1c , respectively. When categorised, the hazard risk (HR) for the updated mean HbA 1c in relation to HF became higher than for baseline and updated latest HbA 1c above HbA 1c levels of 9%, but did not differ at lower HbA 1c levels. The updated latest variable showed an increased risk for HbA 1c <6% (42 mmol/mol) of 1.16 (1.07 to 1.25), relative category 6–7%, while the HRs for updated mean and baseline HbA 1c showed no such J-shaped pattern. Conclusions Hyperglycaemia is still a risk factor for HF in persons with T2D of similar magnitude as in earlier cohorts. Such a relationship exists for current glycaemic levels, at diagnosis and the overall level but the pattern differs for these variables.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [해외논문]   Pre-procedural dual antiplatelet therapy in patients undergoing transcatheter aortic valve implantation increases risk of bleeding   SCI SCIE

    Hioki, Hirofumi (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Watanabe, Yusuke (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Kozuma, Ken (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Nara, Yugo (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Kawashima, Hideyuki (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Kataoka, Akihisa (Division of Cardiology, Department of Internal Medicine, Teikyo University Hospital, , Tokyo, Japan ) , Yamamoto, Masanori (Division of Cardiovascular Medicine, Toyohashi Heart Center, , Aichi, Japan ) , Takagi, Kensuke (Interventional Cardiology Unit, New Tokyo Hospital, , Chiba, Japan ) , Araki, Motoharu (Department of Cardiovascular Medicine, Yokohama City Eastern Hospital, , Kanagawa, Japan ) , Tada, Norio (Department of Cardiovascular Center, Sendai Kosei Hospital, , Miyagi, Japan ) , Shirai, Shinichi (Department of Cardiology, Kokura Memorial Hospital, , Fukuoka, Japan ) , Yamanaka, Futoshi (D) , Hayashida, Kentaro
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 361 - 367 , 2017 , 1355-6037 ,

    초록

    Objective To evaluate the clinical benefit of pre-procedural antiplatelet therapy in patients undergoing transfemoral (TF) transcatheter aortic valve implantation (TAVI). Methods OCEAN (Optimized transCathEter vAlvular interveNtion)-TAVI is a prospective, multicentre, observational cohort registry, enrolling 749 patients who underwent TAVI from October 2013 to August 2015 in Japan. We identified 540 patients (median age 85 years, 68.1% female) undergoing TF-TAVI; of these, 80 had no pre-procedural antiplatelet therapy and 460 had antiplatelet therapy. The endpoints were any bleeding (life-threatening, major, and minor bleeding) and thrombotic events (stroke, myocardial infarction, and valve thrombosis) during hospitalisation. Results Patients with dual antiplatelet therapy (DAPT) had a significantly higher incidence of any bleeding than those with single antiplatelet therapy (SAPT) (36.5% vs 27.5%, p=0.049) and no antiplatelet therapy (36.5% vs 21.3%, p=0.010). Patients without pre-procedural antiplatelet therapy did not experience an increased risk of thrombotic events. In multivariable logistic regression analysis, DAPT before TF-TAVI significantly increased any bleeding compared with SAPT (OR 2.05, 95% CI 1.16 to 3.65) and no antiplatelet therapy (OR 2.30, 95% CI 1.08 to 4.90). Conclusions The current study demonstrated that DAPT before TF-TAVI increased the risk of bleeding compared with single or no antiplatelet therapy. Lower intensity antiplatelet therapy was not associated with thrombotic events. In modern practice, it might be reasonable to perform TAVI using single or no pre-procedural antiplatelet therapy with an expectation of no increase of adverse events. Trial registration number UMIN-ID; 000020423; Results.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  10. [해외논문]   Postoperative dyspnoea   SCI SCIE

    Sims, Jason R (Department of Internal Medicine, Mayo Clinic, , Rochester, Minnesota, USA ) , Enriquez-Sarano, Maurice (Division of Cardiovascular Diseases, Mayo Clinic, , Rochester, Minnesota, USA ) , Michelena, Hector I (Division of Cardiovascular Diseases, Mayo Clinic, , Rochester, Minnesota, USA)
    Heart : official journal of the British Cardiac Society v.103 no.5 ,pp. 367 - 367 , 2017 , 1355-6037 ,

    초록

    Clinical introduction A man in his 50s presented with abscessed aortic valve methicillin-sensitive Staphylococcus aureus endocarditis, received intravenous antibiotics and underwent bioprosthetic aortic valve replacement with removal of all infected tissues. He returned 18 days later with severe dyspnoea, subjective fever and bilateral lower extremity oedema. Physical examination revealed tachypnoea and tachycardia without fever, prominent neck CV waves visible at 90°, left parasternal heave, 3/6 holosystolic murmur across the precordium, lung rales and severe peripheral oedema. C reactive protein was 211 mg/L (normal <8 mg/L). Blood cultures were obtained. ECG showed sinus tachycardia and right axis deviation. Transthoracic echocardiogram (TTE) parasternal zoomed short-axis systolic frame (figure 1A, B), apical four-chamber systolic frame (figure 1C) and subcostal continuous wave (CW) Doppler (figure 1D), are shown. Question Given the clinical presentation and TTE findings, what is the diagnosis? Severe tricuspid regurgitation due to extension of endocarditis Aortic valve obstruction resulting in severe pulmonary hypertension Acquired Gerbode defect Aortic valve dehiscence with severe paraprosthetic regurgitation

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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