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European neuropsychopharmacology : the journal of ... 14건

  1. [해외논문]   Contents  


    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. OBC , 2018 , 0924-977x ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  2. [해외논문]   Contents   SCI SCIE


    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. OBC - OBC , 2018 , 0924-977x ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  3. [해외논문]   Editorial Board   SCI SCIE


    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. IFC - IFC , 2018 , 0924-977x ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  4. [해외논문]   ECNP Calendar of Events   SCI SCIE


    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. III - III , 2018 , 0924-977x ,

    초록

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  5. [해외논문]   Clozapine use in patients with schizophrenia and a comorbid substance use disorder: A systematic review   SCI SCIE

    Arranz, Belé (Parc Sanitari Sant Joan de Déu, Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), Sant Boi de Llobregat, Barcelona, Spain ) , n (Bipolar Disorders Unit, Hospital Clinic Barcelona, Institute of Biomedical Research Agusti Pi i Sunyer (IDIBAPS), Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), University of Barcelona, Barcelona, Spain ) , Garriga, Marina (Barcelona Clinic Schizophrenia Unit, Institute of Neuroscience, Hospital Clinic Barcelona, Institute of Biomedical Research Agusti Pi i Sunyer (IDIBAPS), Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), University of Barcelona, Barcelona, Spain ) , Garcí (Parc Sanitari Sant Joan de Déu, Centro de Investigación Biomedica en Red de Salud Mental (CIBERSAM), Sant Boi de Llobregat, Barcelona, Spain) , a-Rizo, Clemente , San, Luis
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 227 - 242 , 2018 , 0924-977x ,

    초록

    Abstract Lifetime prevalence of substance use disorders (SUD) in patients with schizophrenia is nearly 50%. Nicotine, alcohol, and cannabis are the substances most frequently used, with a high percentage of poly-substance users. There are few available data about pharmacological approaches in this population. Amongst antipsychotics, clozapine shows positive evidence in the literature. The aim of the present article is to provide systematic review on the efficacy of clozapine in SUD improvement in schizophrenic patients. PRISMA recommendations were followed (PROSPERO id: CRD42017059299). Five studies for nicotine use and nine studies for SUD (other than nicotine) were analyzed. Regarding nicotine use, results from randomized controlled trials (RCT) have found a decrease in nicotine use after 12 weeks of 200–600mg/day clozapine, as compared with lower doses. In SUD improvement (other than nicotine), RCT have shown superiority of clozapine when compared with risperidone, in short-term studies (from 4 to 12 weeks) performed in cannabis users. In long-term studies (1 year), clozapine was equal to ziprasidone in reducing cannabis use and equal to treatment as usual in reducing alcohol use. We conclude that positive results on nicotine use are scarce and derived from studies with a low degree of evidence. Evidence of clozapine on SUD (other than nicotine) is stronger, especially when clozapine is compared with first generation antipsychotics in poly-substance users. When compared with second generation antipsychotics, clozapine was superior to risperidone but equal to olanzapine or ziprasidone in poly-substance and cannabis users.

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  6. [해외논문]   The concept of violent suicide, its underlying trait and neurobiology: A critical perspective   SCI SCIE

    Ludwig, Birgit (Correspondence to: UAB Mood Disorder Program, Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, SC711 Sparks Center, 1720 2nd Avenue South, Birmingham, AL, USA. Fax: +01 205 975 8463.) , Dwivedi, Yogesh
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 243 - 251 , 2018 , 0924-977x ,

    초록

    Abstract Suicide is one of the leading causes of death and represents a significant public health problem world-wide. Individuals who attempt or die by suicide represent a highly heterogeneous population. Recently, efforts have been made to identify sub-populations and variables to categorize them. A popular dichotomy in suicide research of the past years is violent versus non-violent suicide - based on the method. This dichotomy is important given that there is an association between method of attempted suicide and risk of subsequent death by suicide. The differentiation concerning suicide methods is also critical regarding preventive efforts. In this review, we have tried to approach the concept of violent suicide from different perspectives, including a discussion about its definition and overlapping categories. In addition, we have critically discussed aggression as underlying trait, the question of intent to die, and sociodemographic, environmental, neuropsychological, and neurobiological factors potentially associated with violent suicide.

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    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  7. [해외논문]   DNA methylation of APBA3 and MCF2 in borderline personality disorder: Potential biomarkers for response to psychotherapy   SCI SCIE

    Knoblich, Nora (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany ) , Gundel, Friederike (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany ) , Brü (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany ) , ckmann, Christof (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany ) , Becker-Sadzio, Julia (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany ) , Frischholz, Christian (Department of Psychiatry and Psychotherapy, University of Tuebingen, Tuebingen, Germany) , Nieratschker, Vanessa
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 252 - 263 , 2018 , 0924-977x ,

    초록

    Abstract Borderline personality disorder (BPD) is a severe and complex mental disease associated with high suicidal tendencies and hospitalization rates. Accumulating evidence suggests that epigenetic mechanisms are implicated in the etiology of BPD. A recent epigenome-wide study identified several novel genes which are epigenetically dysregulated in BPD. Those genes include APBA3 and MCF2 . Psychotherapy such as Dialectical Behavior Therapy (DBT), an established treatment for BPD, provides an excellent setting to investigate environmental influences on epigenetic mechanisms in order to identify biomarkers for disease status and therapy success. However, the effects of DBT on epigenetic regulation has only been researched in one previous study analyzing BDNF . In the present study, we aimed to investigate the role of DNA methylation of APBA3 and MCF2 as possible biomarkers for treatment outcome in BPD, whilst validating the previous findings of differential DNA methylation in a cohort of 44 BPD patients and 44 well-matched healthy control individuals. Unexpectedly, we did not detect significant DNA methylation differences between patients and control individuals. However, we found a high correlation between the methylation status of APBA3 and MCF2 and therapy outcome: before DBT treatment, both genes were significantly higher methylated in patients responding to therapy compared to patients that did not respond. Our study is the first to report results pointing to possible predictive epigenetic biomarkers of DBT outcome in BPD patients. Following replication in independent cohorts, our finding could facilitate the development of more personalized therapy concepts for BPD patients by including epigenetic information.

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    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  8. [해외논문]   Transdiagnostic deviant facial recognition for implicit negative emotion in autism and schizophrenia   SCI SCIE

    Ciaramidaro, Angela (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Bö (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , lte, Sven (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Schlitt, Sabine (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Hainz, Daniela (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Poustka, Fritz (Department of Psychiatry, Psychosomatics and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Weber, Bernhard (Dept. of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Goethe-University, Frankfurt/M, Germany ) , Freitag, Christine (Dept. of Psychiatry and Psychotherapy, Charité) , Walter, Henrik (Universitätsmedizin, Berlin, Germany)
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 264 - 275 , 2018 , 0924-977x ,

    초록

    Abstract Impaired facial affect recognition (FAR) is observed in schizophrenia and autism spectrum disorder (ASD) and has been linked to amygdala and fusiform gyrus dysfunction. ASD patient's impairments seem to be more pronounced during implicit rather than explicit FAR, whereas for schizophrenia data are inconsistent. However, there are no studies comparing both patient groups in an identical design. The aim of this three-group study was to identify (i) whether FAR alterations are equally present in both groups, (ii) whether they are present rather during implicit or explicit FAR, (iii) and whether they are conveyed by similar or disorder-specific neural mechanisms. Using fMRI, we investigated neural activation during explicit and implicit negative and neutral FAR in 33 young-adult individuals with ASD, 20 subjects with paranoid-schizophrenia and 25 IQ- and gender-matched controls individuals. Differences in activation patterns between each clinical group and controls, respectively were found exclusively for implicit FAR in amygdala and fusiform gyrus. In addition, the ASD group additionally showed reduced activations in medial prefrontal cortex (PFC), bilateral dorso-lateral PFC, ventro-lateral PFC, posterior-superior temporal sulcus and left temporo-parietal junction. Although subjects with ASD showed more widespread altered activation patterns, a direct comparison between both patient groups did not show disorder-specific deficits in neither patient group. In summary, our findings are consistent with a common neural deficit during implicit negative facial affect recognition in schizophrenia and autism spectrum disorders.

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

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  9. [해외논문]   Selective attention to smoking cues in former smokers   SCI SCIE

    Rehme, Anne K. (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany ) , Bey, Katharina (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany ) , Frommann, Ingo (Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany ) , Mogg, Karin (School of Psychology, University of Southampton, Southampton, United Kingdom ) , Bradley, Brendan P. (School of Psychology, University of Southampton, Southampton, United Kingdom ) , Bludau, Julia (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany ) , Block, Verena (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany ) , Strä (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany ) , ter, Birgitta (Department of Psychiatry, University of British Columbia, Vancouver, Canada ) , Schü (Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany) , tz, Christian G. , Wagner, Michael
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 276 - 284 , 2018 , 0924-977x ,

    초록

    Abstract Repeated drug use modifies the emotional and cognitive processing of drug-associated cues. These changes are supposed to persist even after prolonged abstinence. Several studies demonstrated that smoking cues selectively attract the attention of smokers, but empirical evidence for such an attentional bias among successful quitters is inconclusive. Here, we investigated whether attentional biases persist after smoking cessation. Thirty-eight former smokers, 34 current smokers, and 29 non-smokers participated in a single experimental session. We used three measures of attentional bias for smoking stimuli: A visual probe task with short (500ms) and long (2000ms) picture stimulus durations, and a modified Stroop task with smoking-related and neutral words. Former smokers and current smokers, as compared to non-smokers, showed an attentional bias in visual orienting to smoking pictures in the 500ms condition of the visual probe task. The Stroop interference index of smoking words was negatively related to nicotine dependence in current smokers. Former smokers and mildly dependent smokers, as compared to non-smokers, showed increased interference by smoking words in the Stroop task. Neither current nor former smokers showed an attentional bias in maintained attention (2000ms visual probe task). In conclusion, even after prolonged abstinence smoking cues retain incentive salience in former smokers, who differed from non-smokers on two attentional bias indices. Attentional biases in former smokers operate mainly in early involuntary rather than in controlled processing, and may represent a vulnerability factor for relapse. Therefore, smoking cessation programs should strengthen self-control abilities to prevent relapses.

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  10. [해외논문]   Reduced insulin sensitivity may be related to less striatal glutamate: An 1H-MRS study in healthy non-obese humans   SCI SCIE

    Caravaggio, Fernando (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Iwata, Yusuke (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Plitman, Eric (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Chavez, Sofia (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Borlido, Carol (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Chung, Jun Ku (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Kim, Julia (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Agarwal, Sri Mahavir (Research Imaging Centre, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, Canada M5T 1R8 ) , Gerretsen, Philip (Research Imaging Centre, Centre for Addi) , Remington, Gary , Hahn, Margaret , Graff-Guerrero, Ariel
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology v.28 no.2 ,pp. 285 - 296 , 2018 , 0924-977x ,

    초록

    Abstract Levels of striatal dopamine (DA) may be positively correlated with levels of striatal glutamate (Glu). While reduced insulin sensitivity (%S) has been associated with reduced striatal DA levels in healthy non-obese persons, whether reduced %S is also associated with reduced striatal Glu levels has not yet been established. Using 1 H-MRS, we measured levels of several neurometabolites in the striatum and dorsolateral prefrontal cortex (DLPFC) of seventeen healthy non-obese persons (9 female, mean age: 28.35 ± 9.53). Insulin sensitivity was estimated for each subject from fasting plasma glucose and insulin using the Homeostasis Model Assessment II. We hypothesized that %S would be positively related with levels of Glu and Glu + glutamine (Glx) in the striatum. Exploratory analyses were also conducted between other fasting markers of metabolic health and neurometabolites measured with 1 H-MRS. In the right striatum, %S was positively correlated with levels of Glu (r(15) = .49, p = .04) and Glx (r(15) = .50, p = .04). In the left striatum, there was a trend positive correlation between %S and Glu (r(15) = .46, p = .06), but not Glx levels (r(15) = .20, p = .44). The relationships between %S and striatal Glu levels remained after controlling for age, sex, and BMI (right: r (12) = .73, β = .52, t = 2.55, p = .03; left: ( r (12) = .63, β = .53, t = 2.25, p = .04) These preliminary findings suggest that %S may be related to markers of glutamatergic functioning in the striatum of healthy non-obese persons. These findings warrant replication in larger samples and extension into neuropsychiatric populations where altered striatal DA, Glu, and %S are implicated.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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