본문 바로가기
HOME> 저널/프로시딩 > 저널/프로시딩 검색상세

저널/프로시딩 상세정보

권호별목차 / 소장처보기

H : 소장처정보

T : 목차정보

Evidence-based medicine 20건

  1. [해외논문]   Wrong guidelines: why and how often they occur  

    Iannone, Primiano (Emergency Department, Ospedale del Tigullio, , Lavagna, Genova, Italy ) , Montano, Nicola (Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico Dipartimento di Scienze Cliniche e di Comunità) , Minardi, Monica (Universitàà' degli Studi di Milano, , Milano, Italy ) , Doyle, James (Emergency and Intensive Care Department, Royal Surrey County Hospital NHS Foundation Trust, , Guildford, UK ) , Cavagnaro, Paolo (Emergency and Intensive Care Department, Royal Surrey County Hospital NHS Foundation Trust, , Guildford, UK ) , Cartabellotta, Antonino (Azienda Sanitaria Locale 3, , Genova, Italy )
    Evidence-based medicine v.22 no.1 ,pp. 1 - 3 , 2017 , 1356-5524 ,

    초록

    Evidence-based guidelines are considered an essential tool in assisting physicians, policymakers and patients when choosing among alternative care options and are considered unbiased standards of care. Unfortunately, depending on how their reliability is measured, up to 50% of guidelines can be considered untrustworthy. This carries serious consequences for patients' safety, resource use and health economics burden. Although conflict of interests, panel composition and methodological flaws are traditionally thought to be the main reasons undermining their untrustworthiness, corruption and waste of biomedical research also contribute. We discuss these issues in the hope for a wider awareness of the limits of guidelines.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  2. [해외논문]   Wrong guidelines: how to detect them and what to do in the case of flawed recommendations  

    Iannone, Primiano (Emergency Department, Ospedale del Tigullio, , Lavagna, Italy ) , Costantino, Giorgio (Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico Dipartimento di Scienze Cliniche e di Comunità) , Montano, Nicola (Universitàà' degli Studi di Milano, , Milano, Italy ) , Podda, Gian Marco (Fondazione Ca' Granda IRCCS Ospedale Maggiore Policlinico Dipartimento di Scienze Cliniche e di Comunità) , Minardi, Monica (Universitàà' degli Studi di Milano, , Milano, Italy ) , Doyle, James (U.O. Medicina III Ospedale San Paolo, , Milano, Italy ) , Cartabellotta, Antonino (Emergency and Intensive Care Department, Royal Surrey County Hospital NHS Foundation Trust, , Guildford, UK )
    Evidence-based medicine v.22 no.1 ,pp. 4 - 8 , 2017 , 1356-5524 ,

    초록

    Any evidence-based recommendation needs careful assessment of its methodological background as well as of its content trustworthiness, especially given that following it will not necessarily produce the intended clinical outcomes. There are no established instruments to evaluate guidelines for their content, while useful tools assessing the quality of methods followed are well recognised and adopted. We suggest a ‘safety bundle’ considering methodological aspects and content trustworthiness of guidelines, by adopting the GRADE method in a backward fashion. Sharing the critical analysis of the guidelines with patients, including any eventual uncertainty about them, is of key importance in order to avoid the possible adverse effects derived from following the wrong guidelines. Such critical approach is also helpful and beneficial in producing better care pathways, health policy decisions and more relevant and ethical research.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  3. [해외논문]   Evidence-based medicine: a persisting desire under fire  

    Alahdab, Fares (Mayo Clinic, , Rochester, Minnesota, USA ) , Alabed, Samer (Mayo Clinic, , Rochester, Minnesota, USA ) , Al-Moujahed, Ahmed (Mayo Clinic, , Rochester, Minnesota, USA ) , Al Sallakh, Mohammad Anass (Mayo Clinic, , Rochester, Minnesota, USA ) , Alyousef, Tareq (Mayo Clinic, , Rochester, Minnesota, USA ) , Alsharif, Ubai (Mayo Clinic, , Rochester, Minnesota, USA ) , Fares, Munes (Mayo Clinic, , Rochester, Minnesota, USA ) , Murad, M Hassan (Mayo Clinic, , Rochester, Minnesota, USA)
    Evidence-based medicine v.22 no.1 ,pp. 9 - 11 , 2017 , 1356-5524 ,

    초록

    Healthcare infrastructure and medical schools in Syria have been greatly compromised by military conflict and humanitarian disaster. Medical students and healthcare professionals reached out for remote learning opportunities. Surprisingly, they desired a curriculum in evidence-based medicine. We report on a curriculum that was delivered to 126 learners using an online remote delivery platform. This experience demonstrates the feasibility of this approach in disaster-stricken areas and underscores the importance of evidence-based medicine even under such conditions.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  4. [해외논문]   Informing treatment decisions through meta-analysis: to network or not?  

    Al Wattar, Bassel H (Women's Health Research Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK ) , Zamora, Javier (Women's Health Research Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK ) , Khan, Khalid S (Women's Health Research Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK)
    Evidence-based medicine v.22 no.1 ,pp. 12 - 15 , 2017 , 1356-5524 ,

    초록

    Evidence from randomised trials and their meta-analyses is typically formed of head-to-head comparisons of a couple of treatments; multiarm trials are infrequent. However, in real-life healthcare, there are many more than two treatment options for a particular condition. To be relevant for the shop-floor of practice, evidence-based medicine requires the use a comprehensive approach to compile, compare and contrast evidence on all options in one synthesis. Network meta-analysis (NMA) offers exactly such a solution. It generates a rank order of the available treatments for practitioners and policymakers that has the merit of objectivity. However, reviewers should make transparent the limitations of NMA as it uses direct and indirect comparisons, inevitably collating data with a certain degree of heterogeneity. This approach is increasingly being deployed to underpin evidence syntheses for incorporating research into practice.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  5. [해외논문]   Cholesterol paradox: a correlate does not a surrogate make  

    DuBroff, Robert (The University of New Mexico School of Medicine, Albuquerque, New Mexico, USA)
    Evidence-based medicine v.22 no.1 ,pp. 15 - 19 , 2017 , 1356-5524 ,

    초록

    The global campaign to lower cholesterol by diet and drugs has failed to thwart the developing pandemic of coronary heart disease around the world. Some experts believe this failure is due to the explosive rise in obesity and diabetes, but it is equally plausible that the cholesterol hypothesis, which posits that lowering cholesterol prevents cardiovascular disease, is incorrect. The recently presented ACCELERATE trial dumbfounded many experts by failing to demonstrate any cardiovascular benefit of evacetrapib despite dramatically lowering low-density lipoprotein cholesterol and raising high-density lipoprotein cholesterol in high-risk patients with coronary disease. This clinical trial adds to a growing volume of knowledge that challenges the validity of the cholesterol hypothesis and the utility of cholesterol as a surrogate end point. Inadvertently, the cholesterol hypothesis may have even contributed to this pandemic. This perspective critically reviews this evidence and our reluctance to acknowledge contradictory information.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  6. [해외논문]   Grading the quality of evidence in complex interventions: a guide for evidence-based practitioners  

    Murad, M Hassan (Evidence-based Practice Center, Mayo Clinic, , Rochester, Minnesota, USA ) , Almasri, Jehad (Evidence-based Practice Center, Mayo Clinic, , Rochester, Minnesota, USA ) , Alsawas, Mouaz (Evidence-based Practice Center, Mayo Clinic, , Rochester, Minnesota, USA ) , Farah, Wigdan (Evidence-based Practice Center, Mayo Clinic, , Rochester, Minnesota, USA)
    Evidence-based medicine v.22 no.1 ,pp. 20 - 22 , 2017 , 1356-5524 ,

    초록

    Evidence-based practitioners who want to apply evidence from complex interventions to the care of their patients are often challenged by the difficulty of grading the quality of this evidence. Using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach and an illustrative example, we propose a framework for evaluating the quality of evidence that depends on obtaining feedback from the evidence user (eg, guideline panel) to inform: (1) proper framing of the question, (2) judgements about directness and consistency of evidence and (3) the need for additional contextual and qualitative evidence. Using this framework, different evidence users and based on their needs would consider the same evidence as high, moderate, low or very low.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  7. [해외논문]   Scoping systematic review on the extent, nature and quality of evidence underlying ophthalmic and paraophthalmic education  

    Williams, Michael (Centre for Medical Education, Queen's University of Belfast, , Belfast, UK ) , Boohan, Mairead (Centre for Medical Education, Queen's University of Belfast, , Belfast, UK ) , Thurston, Allen (Centre for Medical Education, Queen's University of Belfast, , Belfast, UK)
    Evidence-based medicine v.22 no.1 ,pp. 23 - 26 , 2017 , 1356-5524 ,

    초록

    Background Effective education of relevant professionals underpins provision of quality eye healthcare. Objectives This scoping systematic review had 2 aims: first to investigate the extent and nature of scholarly output published on ophthalmic and paraophthalmic education, and second to focus on the quality of reporting of randomised controlled trials (RCTs) identified. Study selection A search strategy was created and applied to PubMed. Any scholarly publications on any aspect of education of those involved in the care of patients with visual problems as the main theme or context was selected. Predefined data were extracted. Findings Of 255 studies included, the most common type of scholarly publications were descriptions of an educational innovation, opinion pieces and descriptive studies. RCTs made up 5.5% of the sample. Most of the 14 RCTs failed to report most of the items recommended in the CONSORT guidelines. Conclusions This review highlights the need for investigators, ethical committees and journals to insist on a better quality of RCT conduct than is presently apparent, but also that clinicians should not be blind to the strengths of non-RCT-based studies in the field of education.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  8. [해외논문]   Intraoperative on-table endoscopic retrograde cholangiopancreatography (ERCP) is better than laparoscopic bile duct exploration for concomitant bile duct stones during emergency laparoscopic cholecystectomy  

    Garg, Pramod Kumar (Department of Gastroenterology, All India Institute of Medical Sciences, , New Delhi, Delhi, India ) , Bansal, Virinder Kumar (Department of Surgical Disciplines, All India Institute of Medical Sciences, , New Delhi, Delhi, India)
    Evidence-based medicine v.22 no.1 ,pp. 27 - 27 , 2017 , 1356-5524 ,

    초록

    Background Effective education of relevant professionals underpins provision of quality eye healthcare. Objectives This scoping systematic review had 2 aims: first to investigate the extent and nature of scholarly output published on ophthalmic and paraophthalmic education, and second to focus on the quality of reporting of randomised controlled trials (RCTs) identified. Study selection A search strategy was created and applied to PubMed. Any scholarly publications on any aspect of education of those involved in the care of patients with visual problems as the main theme or context was selected. Predefined data were extracted. Findings Of 255 studies included, the most common type of scholarly publications were descriptions of an educational innovation, opinion pieces and descriptive studies. RCTs made up 5.5% of the sample. Most of the 14 RCTs failed to report most of the items recommended in the CONSORT guidelines. Conclusions This review highlights the need for investigators, ethical committees and journals to insist on a better quality of RCT conduct than is presently apparent, but also that clinicians should not be blind to the strengths of non-RCT-based studies in the field of education.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  9. [해외논문]   Liraglutide, a GLP-1 receptor agonist, prevents cardiovascular outcomes in patients with type 2 diabetes  

    Doggrell, Sheila A
    Evidence-based medicine v.22 no.1 ,pp. 28 - 28 , 2017 , 1356-5524 ,

    초록

    Background Effective education of relevant professionals underpins provision of quality eye healthcare. Objectives This scoping systematic review had 2 aims: first to investigate the extent and nature of scholarly output published on ophthalmic and paraophthalmic education, and second to focus on the quality of reporting of randomised controlled trials (RCTs) identified. Study selection A search strategy was created and applied to PubMed. Any scholarly publications on any aspect of education of those involved in the care of patients with visual problems as the main theme or context was selected. Predefined data were extracted. Findings Of 255 studies included, the most common type of scholarly publications were descriptions of an educational innovation, opinion pieces and descriptive studies. RCTs made up 5.5% of the sample. Most of the 14 RCTs failed to report most of the items recommended in the CONSORT guidelines. Conclusions This review highlights the need for investigators, ethical committees and journals to insist on a better quality of RCT conduct than is presently apparent, but also that clinicians should not be blind to the strengths of non-RCT-based studies in the field of education.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  10. [해외논문]   Early initiation of antiretroviral therapy prevents HIV transmission to seronegative sexual partners  

    Rutherford, George W (Global Health Sciences, University of California, San Francisco, , San Francisco, California, USA ) , Anglemyer, Andrew (Department of Operations Research, Naval Postgraduate School, , Monterey, California, USA)
    Evidence-based medicine v.22 no.1 ,pp. 29 - 29 , 2017 , 1356-5524 ,

    초록

    Background Effective education of relevant professionals underpins provision of quality eye healthcare. Objectives This scoping systematic review had 2 aims: first to investigate the extent and nature of scholarly output published on ophthalmic and paraophthalmic education, and second to focus on the quality of reporting of randomised controlled trials (RCTs) identified. Study selection A search strategy was created and applied to PubMed. Any scholarly publications on any aspect of education of those involved in the care of patients with visual problems as the main theme or context was selected. Predefined data were extracted. Findings Of 255 studies included, the most common type of scholarly publications were descriptions of an educational innovation, opinion pieces and descriptive studies. RCTs made up 5.5% of the sample. Most of the 14 RCTs failed to report most of the items recommended in the CONSORT guidelines. Conclusions This review highlights the need for investigators, ethical committees and journals to insist on a better quality of RCT conduct than is presently apparent, but also that clinicians should not be blind to the strengths of non-RCT-based studies in the field of education.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지

논문관련 이미지