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Journal of commercial biotechnology 20건

  1. [해외논문]   Biotechnology in India: Emerging opportunities  

    Parmar, Himanshu
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    The global biotechnology and pharmaceutical industry is beleaguered with several challenges such as high R&D costs, increasing regulatory restraints and stagnant product pipelines. Thus, major multinational pharmaceutical and biotechnology companies from the West are increasingly looking for low-cost suitable alternatives. Among the emerging markets, India is seen as a low-cost destination with ample opportunities available to be capitalised on without compromising on the quality. To complement the interest from international community, India is also liberalising its economy and offering increasing opportunities to invest, along with other several reforms undertaken by the government. After information technology (IT), the focus is now on biotechnology in India, as is evident with the release of recent draft of the Biotechnology Policy 2005. This paper offer insights into India's biotechnology sector and opportunities.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  2. [해외논문]   Rethinking innovation in pharmaceutical R&D  

    Baker, Ann , Gill, Jasween
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    The pharmaceutical industry is facing a challenge to be productive. One of the solutions to this problem is for the industry to better harness innovation to deliver more and better drugs through the pipeline. But what is innovation and how can it deliver higher performance through more valuable drugs? Historically, pharmaceutical innovation has been seen to be firmly rooted in discovery. The focus has been on the pursuit of first-in-class products based on new targets. However, new research by CMR International and Accenture challenges the view that investment in this type of innovation alone will solve the productivity gap. The research shows that projects based on new targets (no public data are available on the target and no drugs have been developed for it) are slower and less likely to get to market than those based on known targets. (Either some public data are available but the company has not previously worked on the target, or the company has previously worked on and has experience with the target.) Hence, they substantially increase the risk in pharmaceutical research. In addition, there is evidence that later entrants based on known mechanisms and designed specifically to be best in class often displace first-in-class products in the marketplace. Based on these findings and on wider research into what makes high-performing businesses tick, Accenture believes that companies pursuing high performance need to rethink their innovation strategies. Companies must take a broader view of how and where they innovate. Applying novel approaches throughout the organisation and across the entire R&D process may be the true key to higher levels of productivity. Innovation in discovery is clearly important and the portfolio needs to be carefully balanced to maintain risk within acceptable limits and to deliver expected levels of output. But it is not in itself sufficient.

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  3. [해외논문]   Legal and regulatory update  

    Wilkinson, John
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    The European Commission has launched a public consultation on its proposed amendments to the Medical Devices Directive (MDD) (Dir 93/42/EEC). The aim of the European Commission's proposals is to improve the coherence, transparency and effectiveness of the legislation governing medical devices in line with the recommendations of the report produced in 2002 by the European Commission's Medical Device Experts Group. This report recommended that the requirements for clinical evaluation of medical devices be clarified, transparency be increased by amending post-market surveillance requirements and that the decision making process be improved by empowering the European Commission to make binding decisions where individual national opinions differ on whether a product falls within the definition of 'medical device'. The report also recommended that the three directives governing medical devices (the MDD, the Active Implantable Medical Devices (AIMD) Directive 90/385/EEC and the In-vitro Medical Devices (IVDD) Directive 98/79/EC) should be made more consistent with each other.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   What to do when your technology is good but a licence is terminated  

    Cox, Manon , Adams, Dan
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    One of the biggest challenges in the biotech industry is to secure sufficient funding to support product or technology development. Partnering with companies that have cash and expertise A€“ which, for the most part are larger biotech or pharmaceutical industries A€“ may for many small biotech companies be more appealing than dealing with the financial community A€“ venture capitalists and the like. The risk to the small biotech, however, is enormous because the partner may decide to return the rights to the product. This event usually leaves the product in limbo and the technology used to develop it tainted because of uncertainty regarding the real reasons for the return and the assumption in the world at large that there is something wrong with the product/technology. Thus, the licensor is left in the dark and is faced with 'what's next?' Here our company's strategy to overcome the terminated licence disaster or alternatively to take advantage of the terminated licence opportunity is described.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  5. [해외논문]   The European biotech sector: Could it achieve more?  

    Fazeli, Sam
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    There is a general feeling among investors and other observers that the European biotech sector has not delivered and fund managers complain that there have been very few successes. The author's view is that, although we have not yet reached the heights of the US biotech industry, there have been numerous success stories in Europe. This paper shows that most of the ingredients required for a successful biotech sector already exist in Europe. Most importantly, there is enough cash in Europe to allow companies to bring products to market. The biggest problem is that there is a fragmented equity capital market, which, as well as limiting the pool of capital accessible to individual companies, may also affect the visibility of success. Thus, the success of Actelion and Serono, although known to UK small-cap investors, cannot impact their funds. However, it is time that we stopped complaining about what we do not have and started concentrating on what we do. Companies need to adapt to the realities of the investment environment in Europe. The good news is that we are already seeing some of this reality being taken on board by European companies, where many of them, like the early US biotechs, are aiming at the lower-hanging fruit by picking up products with relatively lower-risk profiles, such as reformulations of existing drugs. This should allow them to start generating their own cash and then take the bigger gambles. Perhaps most important of all and contrary to common belief, as our analysis shows, we do not believe that the amount of cash available to European biotechs is a significant hurdle to achieving success.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  6. [해외논문]   Human Tissue Act 2004: The age of consent arrives in the UK  

    Johnson, Gillian , Wilson, Alex
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    The organ collection scandals of Alder Hey and Bristol Royal Infirmary in the UK were the driving force for a comprehensive overhaul of the legislation and regulation of the handling and use of human tissues in the UK. The Human Tissue Act 2004 is due to come into force in April 2006 and will resolve a number of uncertainties for researchers. The adopted regulatory approach is not dissimilar to that adopted for the use of embryos in the UK. The legislation provides the framework but a body established under the Act A€“ the Human Tissue Authority (HTA) A€“ will be responsible for granting licences, determining what constitutes 'appropriate consent' and providing detailed guidance and regulations. The advantage of this approach is that it will allow the board of the HTA, whose members include experienced professionals in the medical and research communities, to adapt the system to keep up with scientific developments and possibly changes in public opinion more rapidly than would have been possible where guidance is set out within the legislation. Even before the HTA issues its first guidance, researchers can be clear that certain activities, such as those relating to cell lines, are not covered by the Act. Other processes, such as the anonymising and de-linking of patient data could be subject to additional regulation by the HTA although any guidelines must also conform with the provisions of the Data Protection Act 1998. This paper discusses the new regulatory framework and identifies the challenges for researchers in complying with an Act, which provides for criminal sanctions for breach.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  7. [해외논문]   Taking stock in biotechnology futures  

    Jacobs, John L
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    Investors now have a new tool to help them manage the risk associated with biotechnology investment. Individual and professional investors can more confidently invest in companies whose products take years to develop and potentially several more to gain regulatory approvals and commercialise. This paper focuses on the development of the first stock index futures for the biotechnology market. Together, the Chicago Mercantile Exchange and the NASDAQ Stock Market, Inc. have launched an investment product to help reduce risk and foster greater confidence in biotechnology investment. By managing risk in the biotech sector, Biotechnology Index futures should appeal to a broader base of investors while offering greater visibility to biotechs included in the Index.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [해외논문]   Marketspace: Leading therapeutic recombinant protein sales forecast and analysis to 2010  

    Belsey, Mark J , Pavlou, Alex K
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    As part of Datamonitor's biotechnology strategic market analysis, the authors have performed an analysis of the top 20 therapeutic recombinant proteins (defined by 2010 forecast sales), providing a forecast from 2004 to 2010 of product sales by therapeutic and product class. Based on this analysis, which was conducted in June 2005, leading companies operating in this sector are identified. Market analysis indicates that the total compound annual growth rate (CAGR) of these products from 2004 to 2010 is set to be 7.7 per cent, which is lower than other biotech markets such as the monoclonal antibody market. This lower growth rate reflects the mature nature of the therapeutic recombinant protein market. The arthritis, immune and inflammatory disorders franchise is set to record the strongest growth, with a forecast 2004A€“10 CAGR of 16.8 per cent, while the diabetes and endocrinology franchise is set to record the weakest growth (1.6 per cent). The leading product class in terms of total forecast 2010 sales is the erythropoietin class, which is set to generate approximately one-third of total top 20 product sales. The strongest-growing product classes are set to be fusion protein and colony-stimulating factors, while insulins are forecast to be the weakest-growing sector. Amgen is set to continue to lead the recombinant protein market over the forecast period, with the company's contribution to top 20 recombinant protein market sales set to rise from one-third of total 2004 sales to one-half of total 2010 sales.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [해외논문]   Managing innovation in the pharmaceutical industry  

    Schmid, Esther F , Smith, Dennis A
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    Innovation is the lifeblood of the pharmaceutical industry, and has been a major driver of industry growth, as well as providing major advances for patients and society at large during the last century. Despite this record of success, the industry is currently under attack for its perceived lack of innovation. In this paper, data are provided that demonstrate that the pharmaceutical industry today is more innovative than even in its rapid, postwar growth period. The authors discuss in depth a framework for how today's R&D organisations can continue to be innovative.

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  10. [해외논문]   Editorial: De-risking novel therapeutic development A€“ time to stop blaming the molecule?  

    Shohet, Simon
    Journal of commercial biotechnology v.12 no.1 , 2005 , 1462-8732 ,

    초록

    A A

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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