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저널/프로시딩 상세정보

권호별목차 / 소장처보기

H : 소장처정보

T : 목차정보

Epilepsy & behavior : E&B 20건

  1. [해외논문]   Does facial attractiveness influence perception of epilepsy diagnosis? An insight into stigma in epilepsy   SCIE

    Ristić (Center for Epilepsy and Sleep Disorders, Neurology Clinic, Medical School, University of Belgrade, Serbia ) , , Aleksandar J. (Department of Psychology, Faculty of Philosophy, University of Belgrade, Serbia ) , Jovanović (Department of Psychology, Faculty of Philosophy, University of Belgrade, Serbia ) , , Olja (Center for Epilepsy and Sleep Disorders, Neurology Clinic, Medical School, University of Belgrade, Serbia ) , Popadić (Epilepsy Center, Cleveland Clinic, OH, United States ) , , Dragan (Medical School, University of Belgrade, Serbia ) , Pađen, Viš (Center for Epilepsy and Sleep Disorders, Neurology Clinic, Medical School, University of Belgrade, Serbia ) , nja (Center for Epilepsy and Sleep Disorders, Neurology Clinic, Medical School, University of Belgrade, Serbia ) , Moosa, Ahsan N.V. (Clinic for Psychiatry, Medical School, University of Belgrade, Serbia ) , Krivokapić (Neurosurgery Clinic, Medical School, University of Belgrade, Serbia ) , , Ana (Center for Epilepsy and Sleep Disorders, Neurology Clinic, Medical School, University of Belgrade, Serbia ) , Parojč (Center for Epilepsy and Sleep Disorders, Neurology) , ić , , Aleksandra , Berisavac, Ivana , Ilanković , , Andrej , Baš , č , arević , , Vladimir , Vojvodić , , Nikola , Sokić , , Dragoslav
    Epilepsy & behavior : E&B v.77 ,pp. 1 - 7 , 2017 , 1525-5050 ,

    초록

    Abstract Background Using a group of young healthy individuals and patients with multiple sclerosis (pMS), we aimed to investigate whether the physical attractiveness judgment affects perception of epilepsy. We tested hypothesis that subjects, in the absence of relevant clues, would catch upon the facial attractiveness when asked to speculate which person suffers epilepsy and select less attractive choices. Method Two photo-arrays (7 photos for each gender) selected from the Chicago Face Database (180 neutral faces of Caucasian volunteers with unknown medical status) were shown to study participants. Photos were evenly distributed along a continuum of attractiveness that was estimated by independent raters in prestudy stage. In each photo-array, three photos had rating 1–3 (unattractive), one photo had rating 4 (neutral), and three photos had rating 5–7 (attractive). High-quality printed photo-arrays were presented to test subjects, and they were asked to select one person from each photo-array “who has epilepsy”. Finally, all subjects were asked to complete questionnaire of self-esteem and 19-item Scale of stereotypes toward people with epilepsy. Results In total, 71 students of psychology, anthropology, or andragogy (mean age: 21.6±1.7years; female: 85.9%) and 70 pMS (mean age: 37.9±8years; female: 71.4%) were tested. Majority of students or pMS had no previous personal experience with individuals with epilepsy (63.4%; 47.1%, p=0.052). Male photo was selected as epileptic in the following proportions: students — 84.5% unattractive, 8.5% neutral, and 7% attractive; pMS — 62.9% unattractive, 8.6% neutral, and 28.6% attractive (p=0.003). Female photo was selected as epileptic in the following proportions: students — 38% unattractive, 52.1% neutral, and 9.9% attractive; pMS — 32.9% unattractive, 34.3% neutral, and 32.9% attractive (0.003). Both groups showed very low potential for stigmatization: significantly lower in pMS in 10 items. Patients with multiple sclerosis showed significantly higher self-esteem than students (p=0.007). Conclusion Facial attractiveness influences the perception of diagnosis of epilepsy. Both students and pMS were less willing to attribute epilepsy to attractive person of both genders. Highlights We investigated whether the physical attractiveness judgment affects perception of epilepsy Seven photos of neutral faces of both genders evenly distributed along a continuum of attractiveness were preselected We asked healthy subjects and patients with multiple sclerosis to select one person from photo-arrays “who has epilepsy” Both students and patients with multiple sclerosis were less willing to attribute epilepsy to attractive person of both genders

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  2. [해외논문]   Structural differences in interictal migraine attack after epilepsy: A diffusion tensor imaging analysis   SCIE

    Huang, Qi (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , Lv, Xin (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , He, Yushuang (Beijing Normal University, Beijing, China ) , Wei, Xing (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , Ma, Meigang (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , Liao, Yuhan (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , Qin, Chao (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China ) , Wu, Yuan (Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China)
    Epilepsy & behavior : E&B v.77 ,pp. 8 - 12 , 2017 , 1525-5050 ,

    초록

    Abstract Objective Patients with epilepsy (PWE) are more likely to suffer from migraine attack, and aberrant white matter (WM) organization may be the mechanism underlying this phenomenon. This study aimed to use diffusion tensor imaging (DTI) technique to quantify WM structural differences in PWE with interictal migraine. Methods Diffusion tensor imaging data were acquired in 13 PWE with migraine and 12 PWE without migraine. Diffusion metrics were analyzed using tract-atlas-based spatial statistics analysis. Atlas-based and tract-based spatial statistical analyses were conducted for robustness analysis. Correlation was explored between altered DTI metrics and clinical parameters. Results The main results are as follows: (i) Axonal damage plays a key role in PWE with interictal migraine. (ii) Significant diffusing alterations included higher fractional anisotropy (FA) in the fornix, higher mean diffusivity (MD) in the middle cerebellar peduncle (CP), left superior CP, and right uncinate fasciculus, and higher axial diffusivity (AD) in the middle CP and right medial lemniscus. (iii) Diffusion tensor imaging metrics has the tendency of correlation with seizure/migraine type and duration. Conclusion Results indicate that characteristic structural impairments exist in PWE with interictal migraine. Epilepsy may contribute to migraine by altering WMs in the brain stem. White matter tracts in the fornix and right uncinate fasciculus also mediate migraine after epilepsy. This finding may improve our understanding of the pathological mechanisms underlying migraine attack after epilepsy. Highlights Diffusion metrics are significantly altered in patients with epilepsy (PWE) and migraine. Axonal damage plays a key role in PWE with interictal migraine. Epilepsy may contribute to migraine by altering white matters (WMs) in the brain stem. White matters in fornix and right uncinate fasciculus also mediate migraine after epilepsy.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  3. [해외논문]   Epilepsy may be the major risk factor of mental retardation in children with tuberous sclerosis: A retrospective cohort study   SCIE

    Wang, Yang-Yang (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China ) , Pang, Ling-Yu (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China ) , Ma, Shu-Fang (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China ) , Zhang, Meng-Na (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China ) , Liu, Li-Ying (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China ) , Zou, Li-Ping (Department of Paediatrics, Chinese PLA General Hospital, Beijing 100853, China)
    Epilepsy & behavior : E&B v.77 ,pp. 13 - 18 , 2017 , 1525-5050 ,

    초록

    Abstract Mental retardation (MR) is one of the most common cognitive comorbidities in children with tuberous sclerosis, and there are enormous studies about its risk factors. The genetic difference and the severity of epilepsy are the two main factors, but their weight in the occurrence of MR is still unclear. Two hundred twenty-three patients with tuberous sclerosis who received intelligence assessment, genetic mutation analysis, and the epilepsy severity assessment were included in our study. Genotype–neurocognitive phenotype correlations and epilepsy–neurocognitive phenotype correlations were analyzed by binary logistic regression analysis. No statistical significant result was found on genotype–neurocognitive phenotype correlations, which contrasted the previous report. The prevalence of MR was 50.0% for the patients with tuberous sclerosis complex-1 (TSC1) mutation, 54.5% for TSC2 ( p = 0.561), 54.7% for patients with protein-truncating (PT) and 50.0% for patients with nontruncating (NT) ( p = 0.791), and 54.3% for patients with family history and 53.7% for patients without family history ( p = 0.748). Statistical significant results were found on epilepsy–neurocognitive phenotype correlations, both on E-chess score ( p = 0.01) and the occurrence of infantile spasms ( p = 0.014), which was consistent to the previous study. For children with tuberous sclerosis, instead of genetic factors, epilepsy may play the main role for the presence of mental retardation. Patients with mental retardation tend to have earlier seizure attack, take more AEDs, have more seizure types, and have higher seizure frequency. Among the four cognitive functions in Denver II, social ability and language ability are more vulnerable to be influenced than fine and gross motor ability. Highlights For children, the influence of genotype on mental development is little. The presence of infantile spasm and the severity of epilepsy are strongly related to mental retardation. E-chess score can reflect the severity of epilepsy, but the difference in patients with or without mental retardation is little.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   Functional hemispherectomy is safe and effective in adult patients with epilepsy   SCIE

    Schmeiser, Barbara (Department of Neurosurgery, Medical Center —) , Zentner, Josef (University of Freiburg, Breisacherstrasse 64, 79106 Freiburg, Germany ) , Steinhoff, Bernhard Jochen (Department of Neurosurgery, Medical Center —) , Schulze-Bonhage, Andreas (University of Freiburg, Breisacherstrasse 64, 79106 Freiburg, Germany ) , Kogias, Evangelos (Epilepsy Center Kork, Landstrasse 1, 77694 Kehl, Germany ) , Wendling, Anne-Sophie (Epilepsy Center, Medical Center —) , Hammen, Thilo (University of Freiburg, Breisacherstrasse 64, 79106 Freiburg, Germany )
    Epilepsy & behavior : E&B v.77 ,pp. 19 - 25 , 2017 , 1525-5050 ,

    초록

    Abstract Introduction Functional hemispherectomy (FH) is a well-established therapeutic option for children with epilepsy with parenchymal damage confined to one hemisphere, yet its application in adults remains rare. The intention of our study was to investigate postoperative clinical and epileptological outcome in adults who received FH for intractable epilepsy. Materials and methods We retrospectively analyzed 12 adult patients (18–56years) with intractable epilepsy due to unihemispheric pathology. All patients underwent FH. Postoperative neurological and cognitive outcome as well as seizure status were evaluated with a mean follow-up period of 4.9years. Results Ten patients (83%) were seizure-free (Engel I), and two (17%) had recurrent seizures at last follow-up. Apart from one patient requiring operative revision for bone flap infection, no perioperative morbidity or mortality occurred. Postoperative functional assessment revealed deterioration of motor function in 7 patients, whereas 5 remained unchanged. Language was unchanged in 8 patients. The absence of background slowing in preoperative electroencephalogram (EEG) as well as ictal and interictal EEG patterns located ipsilateral to the side of surgery was associated with favorable seizure outcome. Conclusion Favorable seizure control and acceptable functional outcome can be achieved by FH in adults with intractable epilepsy. The risk of postoperative deficits is moderate and even older patients are able to manage postoperative motor impairment. Therefore, FH should be considered in case of unihemispheric lesions also in adults. Highlights Functional hemispherectomy is a safe and effective procedure in adults with intractable unihemispheric epilepsy. Older patients are able to manage postoperative motor impairment with a high chance of seizure freedom. Functional hemispherectomy should be considered in case of unilateral lesion.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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    Fig. 1 이미지
  5. [해외논문]   Effects of continuous theta burst transcranial magnetic stimulation on cortical excitability in patients with idiopathic generalized epilepsy   SCIE

    Koc, Guray (Corresponding author.) , Gokcil, Zeki , Bek, Semai , Kasikci, Tayfun , Eroglu, Erdal , Odabasi, Zeki
    Epilepsy & behavior : E&B v.77 ,pp. 26 - 29 , 2017 , 1525-5050 ,

    초록

    Abstract Introduction Transcranial magnetic stimulation (TMS) is a noninvasive technique for investigating cortical physiologic functions in the brain. In this study, the effects of continuous theta burst stimulation (cTBS) on motor evoked potential (MEP) parameters in patients with idiopathic generalized epilepsy (IGE) were investigated. Materials and methods Fifteen patients with IGE were included. Motor threshold (MT) and cortical silent period (CSP) were determined before cTBS application. Next, cTBS was applied to the dominant (left) hemisphere M1 hand area as the first application. After 1 day, cTBS was applied first to the left M1 hand area and then to the right lateral cerebellar area as the second application. Parameters were again determined after the applications. Results There was no difference in resting MT values before and after cTBS application (p>0.05). Although CSP increased after stimulation (p 0.05). Conclusion For patients with epilepsy, cTBS is a safe technique when applied at a low intensity. The inhibitory effect of cTBS, a noninvasive technique, on cortical excitability in patients with IGE was determined using MEP parameters. The effect lasted at least 1 h. To our knowledge, this is the first study to assess the effect of cTBS on cortical excitability in patients with IGE. Our findings indicate that cTBS decreases cortical excitability in patients with IGE. Highlights Delirium is a common complication in elderly patients after surgery. Preoperative severe hypoalbuminemia (defined as serum albumin ≤30.0g/L) is independently associated with an increased risk of developing postoperative delirium; it is also associated with other worse outcomes after surgery. Whether prophylactic correction of preoperative severe hypoalbuminemia can improve postoperative outcomes of elderly patients is still unknown.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  6. [해외논문]   Long-term forgetting in temporal lobe epilepsy: Is this phenomenon a norm?   SCIE

    Contador, Israel (Department of Basic Psychology, Psychobiology and Methodology of Behavioral Science, University of Salamanca, Salamanca, Spain ) , Sá (Department of Basic Psychology, Psychobiology and Methodology of Behavioral Science, University of Salamanca, Salamanca, Spain ) , nchez, Abraham (King's College, London, UK ) , Kopelman, Michael D. (EEG-Epilepsy Unit, Department of Neurology, University Hospital “12 de Octubre”, Madrid, Spain) , Gonzá , lez de la Aleja, Jesú , s
    Epilepsy & behavior : E&B v.77 ,pp. 30 - 32 , 2017 , 1525-5050 ,

    초록

    Abstract Objectives This research investigated forgetting rates of patients with temporal lobe epilepsy (TLE) at brief and longer intervals. Methods The sample is formed by 5 patients with TLE and 10 healthy individuals. One of the patients received the diagnosis of transient epileptic amnesia (TEA). All patients underwent a standardized clinical protocol for diagnosis including a comprehensive neuropsychological assessment. In addition, two experimental tasks were used to assess the forgetting rates at 4 intervals (30s, 10min, 1day, and 1week): a story task to evaluate verbal cued recall and a route task to assess visuospatial cued recall. Results There were no significant differences between groups in forgetting rates. Conclusions These findings suggest that forgetting patterns in patients with TLE may be heterogeneous, and the presence of accelerated long-term forgetting is not universal.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  7. [해외논문]   Kindling epileptogenesis and panic-like behavior: Their bidirectional connection and contribution to epilepsy-associated depression   SCIE

    Medel-Matus, Jesú (Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA ) , s-Servando (Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA ) , Shin, Don (Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA ) , Sankar, Raman (Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA) , Mazarati, Andrey
    Epilepsy & behavior : E&B v.77 ,pp. 33 - 38 , 2017 , 1525-5050 ,

    초록

    Abstract Anxiety is one of the most common comorbidities of epilepsy, which has major detrimental effects on the quality of life. Generalized anxiety disorder (GAD) associated with epilepsy has been receiving most attention. However, several other forms of anxiety reportedly present in patients with epilepsy, including panic disorder (PD). In this study, using an animal model of limbic epilepsy, we examined the interplay between epilepsy and panic-like behavior (PLB). Further, considering the high degree of comorbidity between depression on the one hand, and both epilepsy and PD on the other hand, we studied whether and how the presence of PLB in animals with epilepsy would affect their performance in depression-relevant tests. Fifty-day-old male Wistar rats were subjected to repeated alternating electrical stimulations of the basolateral amygdala (BLA) to induce kindling of limbic seizures, and the dorsal periaqueductal gray (DPAG) to induce panic-like episodes. Seizure susceptibility and panic reaction threshold were examined before the first and 24h after the last stimulation. At the end of the stimulations, the rats were examined in depression-relevant tests: saccharin preference test (SPT) for anhedonia and forced swimming test (FST) for despair/hopelessness. With regard to kindling, BLA+DPAG stimulation induced more profound increase of seizure susceptibility than BLA stimulation alone (evident as the reduction of the afterdischarge threshold and the increase of the afterdischarge duration). With regard to PLB, the BLA+DPAG stimulation exacerbated the severity of panic-like episodes, as compared with the DPAG stimulation alone. Basolateral amygdala stimulation alone had no effects on panic-like reactions, and DPAG stimulation alone did not modify kindling epileptogenesis. Combined stimulation of BLA and DPAG induced depressive-like behavioral impairments. This is the first experimental study showing bidirectional, mutually exacerbating effect of epilepsy and PLB, and the precipitation of depressive-like state by the epilepsy–PLB comorbidity. Highlights Rats were stimulated in BLA & DPAG to induce epileptic state & PD susceptibility. Pre- & poststimulation, ictogenesis was examined, & depression was characterized. BLA+DPAG stimulations increased both seizure severity and PD susceptibility. Bidirectional detrimental effects of kindling and PD contribute to depression.

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    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [해외논문]   The association of psychosocial variables with adherence to antiepileptic drugs in patients with temporal lobe epilepsy   SCIE

    Wang, Shan (Corresponding author at: Epilepsy Center, Department of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.) , Chen, Cong , Jin, Bo , Yang, Linglin , Ding, Yao , Guo, Yi , Chen, Yi , Wang, Shuang , Ding, Meiping
    Epilepsy & behavior : E&B v.77 ,pp. 39 - 43 , 2017 , 1525-5050 ,

    초록

    Abstract Objective The aim of this study was to explore the association between psychosocial factors and adherence to antiepileptic drugs (AEDs) in patients with temporal lobe epilepsy (TLE). Methods This cross-sectional study was conducted with 123 individuals with TLE, admitted to our epilepsy center from December 2015 to May 2017. The participants completed standardized self-report questionnaires measuring medication adherence, anxiety, depression, and family and social support. Adherence was measured by the 8-item Morisky Medication Adherence Scale (MMAS), and logistic regression was used to examine statistically significant associations of different variables with adherence. Results We found a 33.3% rate of poor AED adherence. Moderate-to-severe anxiety (odds ratio (OR)=2.851, 95% confidence interval (CI)=1.138–7.144, P = 0.025) and the presence of hippocampal sclerosis (OR=3.098, 95% CI=1.259–7.620, P = 0.014) were positively associated with poor adherence to antiepileptic drugs. Social support (OR=0.925, 95% CI=0.863–0.990, P = 0.025) was negatively associated with poor adherence. Neither depression nor family support was associated with adherence. Conclusion One-third of patients with TLE were prone to poor AED adherence, especially individuals with hippocampal sclerosis. Intervention approaches designed to improve AED adherence in patients with TLE should focus on psychosocial factors. Highlights 33.3% of patients with temporal lobe epilepsy (TLE) had poor AED adherence. AED adherence was especially poor in patients with TLE with hippocampal sclerosis. Poor AED adherence was more likely in patients with TLE with anxiety and poor social support.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [해외논문]   Understanding variability in driving recommendations for patients with seizures   SCIE

    Mahmud, Sidrah (Corresponding author.) , Hwang, Sean T.
    Epilepsy & behavior : E&B v.77 ,pp. 44 - 49 , 2017 , 1525-5050 ,

    초록

    Abstract Background There is lack of consensus regarding driving restrictions for patients with epilepsy. Regulations vary by state. New York State (NYS) recommends driving restrictions for one year in a person with an episode of loss of consciousness (LOC), with physician discretion. Often, providers make recommendations to permit their patients to drive after a shorter seizure-free period than proposed guidelines. The prevalence and reasons behind more lenient recommendations have not been elucidated. Methods Forty-one neurologists were surveyed anonymously in Nassau County, New York. They were questioned about the length of recommended driving restrictions (≤1, 3, 6, or ≥12months) that they typically provide to patients with suspected seizures in different clinical scenarios and overall reasons for doing so. Data about level of training, setting of practice, use of antiepileptic drug (AED) levels, and electroencephalogram (EEG) were also collected. Results Of the 41 neurologists surveyed, 72% reported recommending driving restrictions Conclusion We found that many neurologists' recommendations for limiting driving for patients with seizure-related episodes are shorter than those recommended by NYS. Furthermore, as there are no specific guidelines for questionable epileptic scenarios and seizures occurring nocturnally or without LOC, this appears to contribute to substantial variability in the duration of recommended driving restrictions. This opens a broad discussion about approaches towards advising driving limitations in order to protect public and patient safety while maintaining patient autonomy. Highlights Recommendations among neurologists for driving restrictions in patients with epilepsy vary widely. Physicians are willing to make exceptions regarding the duration of restriction based on certain clinical circumstances. Reasons include: patient autonomy, diagnostic uncertainty, and events occurring nocturnally or without loss of awareness.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

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  10. [해외논문]   A simple clinical score for prediction of nonepileptic seizures   SCIE

    Rao, Sindhu R. (Corresponding author at: Department of Neurology, University of Florida, PO Box 100236, Gainesville FL 32610, USA.) , Slater, Jeremy D. , Kalamangalam, Giridhar P.
    Epilepsy & behavior : E&B v.77 ,pp. 50 - 52 , 2017 , 1525-5050 ,

    초록

    Abstract Psychogenic nonepileptic seizures (PNES), often mistaken for epilepsy in community practice, require inpatient video-EEG (VEEG) monitoring for diagnostic confirmation. We developed a simple score designed for use in an outpatient setting to predict the subsequent VEEG diagnosis of PNES. We retrospectively compared fifty-five consecutive patients with VEEG-proven PNES ( N 1 = 55) with a group of randomly selected patients with VEEG-proven epilepsy ( N 2 = 55). Patients were divided into two groups: I) a ‘truly retrospective’ group of 27 patients with PNES and 27 patients with epilepsy whose data served to develop the score, and II) a ‘pseudoprospective’ group of 28 patients each with PNES and epilepsy to whom the score was applied. Six features in the history of the Group I cohort appeared more prominent in patients with PNES than patients with epilepsy and were assigned escalating numerical values as follows: number of declared drug allergies (0, 0.5, 1), number of declared comorbidities (0, 0.5, 1), number of previous invasive medical interventions of any type (0, 0.5, 1), and a history of significant psychological or physical trauma (0 or 1). In addition, a score was assigned to verbal description of the seizures themselves as being consistent (=0), atypical (=1), or indeterminate (=0.5) for epilepsy. The values were added to yield an omnibus score ranging from 0 to 6. Scoring of Group II subjects in a blinded fashion revealed that in general patients with PNES had higher scores, and the majority obtained a score >2; most patients with epilepsy scored p

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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