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Journal of pediatric urology 63건

  1. [해외논문]   Editorial Board  


    Journal of pediatric urology v.14 no.3 ,pp. i - i , 2018 , 1477-5131 ,

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  2. [해외논문]   Editorial  

    Caldamone, Anthony , Heloury, Yves , Herndon, C.D. Anthony , Hoebeke, Piet , Wood, Dan
    Journal of pediatric urology v.14 no.3 ,pp. 207 - 207 , 2018 , 1477-5131 ,

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  3. [해외논문]   Obituary – Sami Arap  

    Dé , nes, Francisco Tibor
    Journal of pediatric urology v.14 no.3 ,pp. 208 - 209 , 2018 , 1477-5131 ,

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  4. [해외논문]   Featuring: Has the robot caught up? National trends in utilization, perioperative outcomes, and cost for open, laparoscopic, and robotic pediatric pyeloplasty in the United States from 2003 to 2015  

    Cardona-Grau, Diana (Correspondence to: Diana Cardona-Grau, Division of Pediatric Urology, University of California San Diego, Rady Children's Hospital, 3020 Children's Way MC-5120, San Diego, CA, USA, Tel.: +1 858 576 1700x5715 (office))
    Journal of pediatric urology v.14 no.3 ,pp. 210 - 211 , 2018 , 1477-5131 ,

    초록

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    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  5. [해외논문]   Non-stented versus stented urethroplasty for distal hypospadias repair: A systematic review and meta-analysis  

    Chua, Michael (Division of Urology, The Hospital for Sick Children, Quezon City, ON, Canada ) , Welsh, Christopher (Department of Medicine, University of Ottawa Medical School, Ottawa, Canada ) , Amir, Bisma (Division of Urology, The Hospital for Sick Children, Quezon City, ON, Canada ) , Silangcruz, Jan Michael (Institute of Urology, St. Luke's Medical Center, Quezon City, ON, Canada ) , Ming, Jessica (Division of Urology, The Hospital for Sick Children, Quezon City, ON, Canada ) , Gnech, Michele (Department of Surgery, University of Padua, Padua, Italy ) , Sanger, Stephanie (Health Science Library, McMaster University, Hamilton, ON, Canada ) , Lorenzo, Armando (Division of Urology, The Hospital for Sick Children, Quezon City, ON, Canada ) , Braga, Luis H. (Health Science Library, McMaster University, Hamilton, ON, Canada ) , Bä (Division of Urology, The Hospital for Sick Children, Quezon City, ON, Canada) , gli, Darius
    Journal of pediatric urology v.14 no.3 ,pp. 212 - 219 , 2018 , 1477-5131 ,

    초록

    Summary Introduction Studies have shown that non-stented distal hypospadias repair eliminates stent-related bladder spasm and stent removal discomfort without increasing complications; however, results are inconsistent. We performed a systematic review to assess the complication rates of non-stented compared to the stented distal hypospadias repair. Methods The literature search included randomized control trials (RCTs) and cohort studies published prior to October 2016 in all languages (PROSPERO CRD42016047563). All included studies were assessed according to Cochrane Collaborative recommendations and included for meta-analysis. Surgical outcomes from each treatment group were classified according to early complications and later final outcomes. Outcomes were expressed as relative risk (RR) and 95% confidence intervals (CI). Interstudy heterogeneity was assessed using chi-square and I 2 . Effect estimates were pooled using the inverse variant method with random effect model. Subgroup analysis was performed according to surgical technique (Mathieu versus tubularized incised plate) and study design. Results A total of 20 studies (14 cohorts, 6 RCTs) with 2466 hypospadias repairs (1290 non-stented, 1176 stented) were included for the meta-analysis. Serious risk of bias was noted among the cohort studies with publication bias likely present, while the included RCTs were of moderate methodological quality. The overall pooled effect estimates comparing non-stented versus stented distal hypospadias repair showed no between-group difference for outcomes of early and late complications (RR 0.83, 95% CI 0.46–1.50; RR 0.96, 95% CI 0.92, 1.48; respectively) Conclusions Current evidence of low to moderate quality suggests that there is likely no outcome difference between non-stented and stented distal hypospadias repair.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  6. [해외논문]   Commentary to: 'Non-stented versus stented urethroplasty for distal hypospadias repair: A systematic review and meta-analysis'  

    Merguerian, Paul
    Journal of pediatric urology v.14 no.3 ,pp. 220 - 220 , 2018 , 1477-5131 ,

    초록

    Summary Introduction Studies have shown that non-stented distal hypospadias repair eliminates stent-related bladder spasm and stent removal discomfort without increasing complications; however, results are inconsistent. We performed a systematic review to assess the complication rates of non-stented compared to the stented distal hypospadias repair. Methods The literature search included randomized control trials (RCTs) and cohort studies published prior to October 2016 in all languages (PROSPERO CRD42016047563). All included studies were assessed according to Cochrane Collaborative recommendations and included for meta-analysis. Surgical outcomes from each treatment group were classified according to early complications and later final outcomes. Outcomes were expressed as relative risk (RR) and 95% confidence intervals (CI). Interstudy heterogeneity was assessed using chi-square and I 2 . Effect estimates were pooled using the inverse variant method with random effect model. Subgroup analysis was performed according to surgical technique (Mathieu versus tubularized incised plate) and study design. Results A total of 20 studies (14 cohorts, 6 RCTs) with 2466 hypospadias repairs (1290 non-stented, 1176 stented) were included for the meta-analysis. Serious risk of bias was noted among the cohort studies with publication bias likely present, while the included RCTs were of moderate methodological quality. The overall pooled effect estimates comparing non-stented versus stented distal hypospadias repair showed no between-group difference for outcomes of early and late complications (RR 0.83, 95% CI 0.46–1.50; RR 0.96, 95% CI 0.92, 1.48; respectively) Conclusions Current evidence of low to moderate quality suggests that there is likely no outcome difference between non-stented and stented distal hypospadias repair.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

    이미지

    Fig. 1 이미지
  7. [해외논문]   Response to “Re: Non-stented versus stented urethroplasty for distal hypospadias repair: A systematic review and meta-analysis”  

    Chua, Michael
    Journal of pediatric urology v.14 no.3 ,pp. 221 - 221 , 2018 , 1477-5131 ,

    초록

    Summary Introduction Studies have shown that non-stented distal hypospadias repair eliminates stent-related bladder spasm and stent removal discomfort without increasing complications; however, results are inconsistent. We performed a systematic review to assess the complication rates of non-stented compared to the stented distal hypospadias repair. Methods The literature search included randomized control trials (RCTs) and cohort studies published prior to October 2016 in all languages (PROSPERO CRD42016047563). All included studies were assessed according to Cochrane Collaborative recommendations and included for meta-analysis. Surgical outcomes from each treatment group were classified according to early complications and later final outcomes. Outcomes were expressed as relative risk (RR) and 95% confidence intervals (CI). Interstudy heterogeneity was assessed using chi-square and I 2 . Effect estimates were pooled using the inverse variant method with random effect model. Subgroup analysis was performed according to surgical technique (Mathieu versus tubularized incised plate) and study design. Results A total of 20 studies (14 cohorts, 6 RCTs) with 2466 hypospadias repairs (1290 non-stented, 1176 stented) were included for the meta-analysis. Serious risk of bias was noted among the cohort studies with publication bias likely present, while the included RCTs were of moderate methodological quality. The overall pooled effect estimates comparing non-stented versus stented distal hypospadias repair showed no between-group difference for outcomes of early and late complications (RR 0.83, 95% CI 0.46–1.50; RR 0.96, 95% CI 0.92, 1.48; respectively) Conclusions Current evidence of low to moderate quality suggests that there is likely no outcome difference between non-stented and stented distal hypospadias repair.

    원문보기

    원문보기
    무료다운로드 유료다운로드

    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  8. [해외논문]   Vascular thrombosis in pediatric kidney transplantation: Graft survival is possible with adequate management  

    Gander, Romy (Department of Pediatric Surgery, Pediatric Urology and Renal Transplant Unit, University Hospital Vall d'Hebron, Barcelona, Spain ) , Asensio, Marino (Department of Pediatric Surgery, Pediatric Urology and Renal Transplant Unit, University Hospital Vall d'Hebron, Barcelona, Spain ) , Royo, Gloria Fatou (Department of Pediatric Surgery, Pediatric Urology and Renal Transplant Unit, University Hospital Vall d'Hebron, Barcelona, Spain ) , Molino, José (Department of Pediatric Surgery, Pediatric Urology and Renal Transplant Unit, University Hospital Vall d'Hebron, Barcelona, Spain ) , André (Department of Pediatric Surgery, University Hospital Vall d'Hebron, Barcelona, Spain ) , s (Department of Pediatric Nephrology, University Hospital Vall d'Hebron, Barcelona, Spain ) , Garcí (Department of Pediatric Nephrology, University Hospital Vall d'Hebron, Barcelona, Spain ) , a, Laura (Department of Pediatric Surgery, University Hospital Vall d'Hebron, Barcelona, Spain) , Madrid, Alvaro , Ariceta, Gema , Lopez, Manuel
    Journal of pediatric urology v.14 no.3 ,pp. 222 - 230 , 2018 , 1477-5131 ,

    초록

    Summary Objective Vascular thrombosis (VT) in pediatric kidney transplantation (KT) is a dreaded event that leads to graft loss in almost 100% of cases. In recent years, VT has become the most common cause of early graft loss. The aim of this study was to analyze our experience in diagnosis and treatment of VT and the impact of a new management protocol on patient outcome. Methods We conducted a retrospective study of 176 consecutive KT performed at our institution by the pediatric urology team between January 2000 and December 2015 and identified patients with VT. A protocol of prevention and early detection of VT was introduced in 2012. Results Out of 176 KT, nine cases of VT were identified (5.1%). The mean recipient age was 5.1 years (SD 4.9 years) and mean weight was 22.28 kg (SD 15.6 kg). Diagnosis was intraoperative in two cases and within the first 24 h after surgery in the remaining seven. Immediate surgical exploration was performed after diagnosis in all. Of the five episodes that occurred before 2012, all developed complete graft ischemia requiring transplantectomy. However, in the four cases diagnosed after 2012, graft perfusion could be restored in three, and abdominal wall closure with a mesh and delayed sequentially closure under ultrasound guidance was performed. With a follow-up of 30, 25, and 20 months, the three recovered grafts are still functioning normally. Conclusions Increased awareness and the application of a protocol for prevention, detection and treatment of VT in pediatric KT can prevent graft loss. Immediate surgical intervention is mandatory after diagnosis. Avoiding compartment syndrome with delayed sequential closure may be useful to improve graft survival.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  9. [해외논문]   Role of surgery in localized initially unresectable neuroblastoma  

    Ahmed, Gehad (Faculty of Medicine, Departement of Surgery, Helwan University, Egypt ) , Fawzy, Mohamed (Pediatric Oncology Department, CCHE, Egypt ) , Elmenawi, Salma (Clinical Research Department, CCHE, Egypt ) , Elzomor, Hossam (Pediatric Oncology Department, CCHE, Egypt ) , Yosif, Yasser (Pediatric Oncology Department, CCHE, Egypt ) , Elkinaai, Naglaa (Pathology Department, CCHE, Egypt ) , Refaat, Amal (Radiodiagnosis Department, CCHE, Egypt ) , Hegazy, Mohamed (Anesthesia Department CCHE, Egypt ) , El Shafiey, Maged (Surgical Oncology Department, Children's Cancer Hospital (CCHE) 57357, Egypt)
    Journal of pediatric urology v.14 no.3 ,pp. 231 - 236 , 2018 , 1477-5131 ,

    초록

    Summary Purpose Evaluating the role of surgery and the extent of tumor resection on the outcome of patients with localized initially unresectable neuroblastoma (NB). Patients and methods This was a retrospective case review study including patients with localized initially unresectable NB. The primary tumor was considered unresectable according to imaging defined risk factors (IDRFs). Surgical resection was attempted after four to six courses of chemotherapy. The extent of resection was classified as follows: ≥90% resection, incomplete resection (50–90%) and cases with Results A total of 202 patients with NB were included. Surgical resection was done in 106 patients. It was ≥90% in 89 patients (83.9%). Surgical resection was not performed in 96 patients (47.5%). Fifty-five (57.2%) were in good response after primary chemotherapy and 41 patients (42.7%) had persisting IDRFs, nine of them had biopsy only, and a follow-up strategy was considered in the other 32 patients. The overall 5-year event-free survival (EFS) and overall survival (OS) were 89.1 ± 2.4% and 94.9 ± 1.7%, respectively, with significantly better OS and EFS for patients who had resection versus no resection ( p = 0.003 and 0.04, respectively). There was no impact of extent of resection on EFS and OS in the whole group ( p = 0.91, p = 0.9) and in subgroup analysis stratified by site, histology, and age of the patients. Conclusion In children with localized initially unresectable NB, surgical resection was the only significant risk factor associated with better survival. The extent of tumor resection had no impact on EFS and OS. The concept of accepting incomplete resection to avoid serious complications was successful.

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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  10. [해외논문]   Description of mutation spectrum and polymorphism of Wilms' tumor 1 (WT1) gene in hypospadias patients in the Indonesian population  

    Diposarosa, Rizki (Department of Surgery, Pediatric Surgery Division, Hasan Sadikin Hospital, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Pamungkas, Kurniawan O. (Department of Surgery, Pediatric Surgery Division, Hasan Sadikin Hospital, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Sribudiani, Yunia (Department of Biochemistry and Molecular Biology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Herman, Herry (Department of Surgery, Orthopedic Surgery Division, Hasan Sadikin Hospital, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Suciati, Lita P. (Laboratory of Genetic and Biology Molecular, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Rahayu, Nurul S. (Laboratory of Genetic and Biology Molecular, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia ) , Effendy, Sjarif H. (Clinical Genetics Working Group, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia)
    Journal of pediatric urology v.14 no.3 ,pp. 237.e1 - 237.e7 , 2018 , 1477-5131 ,

    초록

    Summary Introduction Hypospadias is one of the most common congenital anomalies of the penis. Previous studies reported mutation of the Wilms' tumor 1 (WT1) gene as a cause of hypospadias. The aim of this study is to describe the WT1 mutation spectrum and polymorphism in hypospadias patients in Indonesia. Material and methods DNA was isolated from 74 hypospadias patients at the Division of Pediatric Surgery, Department of Surgery Hasan Sadikin Hospital. All exons in the WT1 gene were amplified by a PCR method, followed by Sanger sequencing. Mutation analysis was performed using BioEdit software and in silico analysis using Mutation Taster, Polymorphism Phenotyping-2 (PolyPhen-2), and Sorting Intolerant from Tolerant (SIFT). Result DNA analysis results showed two types of heterozygous mutations in five subjects (Table), hence the frequency of WT1 mutations was 6.7% (10/148 allele). The first mutation was a missense mutation identified in twin boys. The second was a novel heterozygous alteration in the non-coding region nine bp upstream of exon 6 (c.366-9T>C), which was identified in three patients. One heterozygous polymorphism in the coding region of exon 7 (c.471A>G/rs16754) was identified in 10 subjects. This variant did not cause any change in amino acid products (silence polymorphism). Allele frequency for the G allele (mutant allele) and A allele (wild type) was 13.5% and 86.5%, respectively. Discussion WT1 is one of the best known hypospadias genes. The WT1 gene is involved in male genital development in the early and late periods of sex determination, and hence is known as a long-term expression gene in genitalia development. Mutation analysis of WT1 in a Chinese population identified that the WT1 mutation frequency was 4.4%. The WT1 mutation frequency identified in the present study was higher, at 6.7%. Coincidentally, research subjects with p.R158H variants were monozygotic twin siblings with midshaft hypospadias accompanied by undescended testis in one and penoscrotal hypospadia with micropenis in the other. The incidence of familial hypospadias in male siblings suffering from hypospadias was reported to be 9.6% in a study conducted by Sorensen et al. Moreover, in the present study polymorphism c.471A>G(rs16754) at exon 7 was identified heterozygously in 10 research subjects (minor allele frequency 13.5%). Conclusion WT1 mutations were identified in only a few cases of hypospadias and most of these were syndromic. This result implies that mutation of WT1 is not a common cause of hypospadias in the Indonesian population. Table Rare variant gene WT1 Sample number Exon DNA alteration Amino acid alteration Allele SNP Phenotype Type of hypospadias Associated anomalies 5 Int6 c.366-9T>C – Het – Mid-shaft – 6 Int6 c.366-9T>C – Het – Mid-shaft – 41 Int6 c.366-9T>C – Het – Penoscrotal Undescended testisAnorectal malformation 56 7 c.473G>A p.R158H Het rs554416372 Mid-shaft Undescended testis 57 7 c.473G>A p.R158H Het rs554416372 Penoscrotal Micropenis

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    회원님의 원문열람 권한에 따라 열람이 불가능 할 수 있으며 권한이 없는 경우 해당 사이트의 정책에 따라 회원가입 및 유료구매가 필요할 수 있습니다.이동하는 사이트에서의 모든 정보이용은 NDSL과 무관합니다.

    NDSL에서는 해당 원문을 복사서비스하고 있습니다. 아래의 원문복사신청 또는 장바구니담기를 통하여 원문복사서비스 이용이 가능합니다.

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