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H : 소장처정보

T : 목차정보

韓國營養學會誌 = The Korean journal of nutrition. 9건

  1. [국내논문]   Efficiency of ATP Synthesis and Impairment of Glucose Tolerance in the NIDDM-Prone Rat  

    Kim, Sook-Bae (Department of Foods and Nutrition, University of Georgia)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 379 - 385 , 1997 , 0367-6463 ,

    초록

    This study was designed to determine whether genetic defect in the efficiency of ATP synthesis existed in the NIDDM-prone BHE/cdb rat and to determine whether these defect caused the development of glucose intolerance. Thyroxine treatment provided an excellent clue as to the nature of the genetic defects in this rat. The characteristics of hyperthyroid and control Sprague-Dawley(SD) and BHE/cdb rats were studied. Hyperthyroisdism was induced through the addition of thyroxine $(T_4)$ to the diet(2mg/kg of diet). Active proton conductances and passive proton conductances were tested. Mitochondria from hyperhyroid BHE/cdb rats were less efficient in active proton conductances than mitochondria from hyperthyroid SD rats. It showed that decreased efficiency of ATP synthesis in the BHE/cdb rat was probably related to defects inactive proton conductance, indicating aberrant $F_{0}ATPase$ . The levels of $F_{1}F_{0}ATPase$ activity were tested. Mitochondria from hyperhyroid BHE/cdb rats were less active than mitochondria from hyperthyroid SD rats. This may be an attribute of aberrant $F_{1}F_{0}ATPase$ and may contribute to the BHE/cdb strain's characteristic of reduced ATP synthesis efficiency. Glucose tolerances were tested. BHE/cdb rats were profoundly affected by thyroxine, whereas SD rats were less so. It showed that the diabetes phenotype in BHE/cdb rats was related to defects in thyroxine-induced uncoupling. These results showed the decreased efficiency of ATP synthesis due to genetic defects in $F_{1}F_{0}ATPase$ had relevance to the characteristic of impaired glucose tolerance in the NIDDM-prone BHE/cdb rat.

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  2. [국내논문]   The Effect of Dietary Lipids on CVD Risk Factors in Ovariectomized Rats  

    Kwon, Ja-Ryong (Department of Food and Nutrition, Hanyang University ) , Ahn, Hae- Seon (Department of Food and Nutrition, Hanyang University ) , Lee, Sang- Sun (Department of Food and Nutrition, Hanyang University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 386 - 393 , 1997 , 0367-6463 ,

    초록

    This experiment was performed to investigate the effect of different dietary lipids on the risk factors of coronary vascular disease(CVD) in ovariectomized rats. Female rats of Sprague-Dawley strain were divided into sham-operated(sham) and ovariectomized(ovx) groups and then each group was divided into a beef tallow group, a soy bean oil group and a fish oil group. After 16 weeks of feeding on experimental diets, animals were sacrificed and blood, liver, kidney and perirenal fat pad were obtained. Food intake and weight gain of fish oil group were significantly lower than other dietary lipid groups. Food intake and weight gain tended to be higher in ovx groups than in sham groups. The weight index(g/100g body weight) of liver and kidney was higher in the fish oil group than the other groups and weight index was lower in ovx groups compared to sham groups. The weight of the perirenal fat pad was the highest in the beef tallow group and the lowest in the fish oil group. The fish oil group showed the lowest total cholesterol(TC) and triglyceride (TG) levels in serum. Serum TG levels were lower in all ovx groups than in sham groups, but serum TC levels were not influenced by ovariectomy. Fatty acid composition of serum reflects the recent dietary intake of fat. Linoleic acid content was the highest in soy bean oil group and eicosapentaenoic acid(EPA) and docosahexaenoic acid(DHA) contents were the highest in fish oil group. Fatty acid composition of adipose tissue, especially EPA and DHA contents in perirenal fat pad, was highest in the fish oil group. Saturated fatty acid(SFA) and monounsaturated fatty acid(MUFA) in serum and adipose tissue did not reflect fatty acid intake. The activities of glucose-6-phosphate dehydrogenase, a lipogenic enzyme, in the blood of the beef tallow and soybean oil groups showed the tendency to be high and that of fish oil group to be low in ovx. Carnitine acetyltransferase, a lipolytic enzyme, showed the highest activity in the liver of the fish oil group and was least active in the soy bean oil group.

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  3. [국내논문]   Effects of Phytate and Calcium on the Reabsorption of Endogenous Zinc in Zinc-Depleted Rats  

    Kwun, In-Sook (Department of Food Science and Nutrition, College of Human Ecology, Kyungpook National University ) , Oberleas, Donald (Food and Nutrition, Texas Tech University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 394 - 405 , 1997 , 0367-6463 ,

    초록

    Endogenous zinc is important for maintaining zinc homeostasis because the size of endogenous zinc pool is almost 3-4 times bigger than that of dietary zinc. The purpose of this study was to examine the phytate effect on the reabsorption of endogenous zinc and the additional Ca effect on the phytate effect. Rats were fed a casein-based diet with added sodium phytate containing either high(1.6%) or low(0.8%) Ca concentrations for 4 weeks to reduce the body zinc pool. After the depletion period, $^{65}ZN$ was given by intraperitoneal injection to label the endogenous zinc pool. Rats were then assigned into phytate or non-phytate group within the same Ca group. Feces were collected for 2 weeks of the initial collection period and 1 week after dietary crossover. The ratios of excreted fecal $^{65}ZN$ radioactivity of phytate group : non-phytate group were determined as a measure of the phytate effect on the endogenous zinc. Mean fecal $^{65}ZN$ radioactivity was higher in the phytate group than in the non-phytate group during the entire 3 weeks of the collection period in the low Ca group, and during the initial collection period in the high Ca group(p

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  4. [국내논문]   Phytate Effect on the Absorption of Total Zinc in Zinc-Depleted Rats  

    Kwun, In-Sook (Department of Food and Nutrition, Texas Tech University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 406 - 414 , 1997 , 0367-6463 ,

    초록

    It has been known that dietary phytate decreases the absorption of body zinc pool which is composed of the dietary and endogenous zinc in the body. The purpose of this study was to examine the effect of phytate on the absorption of total bodyzinc in Zn-depleted rats. Rats were Zn-depleted with either low(0.8%) or high(1.6%) Ca diet containing sodium phytate for 4 weeks. After zinc depletion, rats were assigned into phytate or non-phytate dietary groups within each low- or high-Ca dietary group. Rat feces were collected for 2 weeks of the initial collection and 1 week after dietary crossover, during which the phytate and the non-phytate diet was switched over within the same Ca group. The content of Zn and Ca measured by atomic absorption spectrophotometer and phytate content was analyzed. Food intake was higher in the high Ca group than in the low Ca group(p

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  5. [국내논문]   Effects of Dietary Fatty Acids on Serum Lipids and Fatty Acid Composition of Serum Phospholipids in Men  

    Oh, Eun-Joo (Department of Food and Nutrition, Hanyang University ) , Kwon, Jong-Sook (Department of Food and Nutrition, Shingu College ) , Chang, Yu-Kyung (Department of Food and Nutrition, Hanyang University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 415 - 424 , 1997 , 0367-6463 ,

    초록

    Serum lipid levels and fatty acid composition of serum phospholipids(PL) were investigated in 24 healthy male subjects who consumed either corn oil(CO) rich in linoleic acid(LA), perilla oil(PO) rich in ${\alpha}-linolenic$ acid( $\alpha-LNA$ ), or canola oil acid(OA) as a major. fat source for 5 weeks. The PO and the CNO groups showed significant(P ${\alpha}-LNA$ and EPA were observed in the CNO group. Arachidonic acid(AA) content of serum PL did not change in the CO group during the study period, although, the increase in LA was significant(P

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  6. [국내논문]   B-6 Vitamers and ${\beta}$-Glucoside Conjugates in Milk of American and Egyptian Women during the First Six Months of Lactation  

    Lee, Jeong-Yeon (Department of Foods and Nutrition, Purdue University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 425 - 433 , 1997 , 0367-6463 ,

    초록

    Levels and distribution of five B-6 vitamers(PMP, PM, PLP, PL, and PN) and pyridoxine ${\beta}$-glucoside$ conjugates(PN-glucoside) were examined in milk of American women who received supplements of 2.5 or 10mg PN HCl/d and of unsupplemented Egyptian women during the first six months of lactation. B-6 vitamer and PN-glucoside levels in human milk were determined by reverse-phase HPLC. Pyridoxal(PL), which has been reported to be the most rapidly absorbed form of vitamin B-6 and may facilitate bioavailability, was the predominant vitamer in human milk of all three groups. Pyridoxal made up 72% of total vitamin B-6 for the 2.5mg supplemented group, 76% for the 10mg group, and 59% for the Egyptian group. Level and percent PL were significantly lower for Egyptian women. Mean growth of the two American groups was similar to each other and within the normal range of the NCHS reference, however, Egyptian infants showed growth faltering at 6 months. The percent of PN-glucoside, a less bioavailable form of vitamin B-6 in humans was 1% in milk of American women and was 11% in Egyptian women and these values were significantly different. For Egyptian women, total vitamin B-6 levels in breast milk correlated positively with animal protein intake(r=0.91) and percent PN-glucosides(r=0.53) and negatively with plant protein intaker(r= -0.55). These findings showed that high plant protein intake was associated with low concentrations of PL and total vitamin B-6 in human milk.

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  7. [국내논문]   The Effect of Nutrition Knowledge and Attitudes on Fat Consumption Using 1989/1991 Continuing Survey of Food Intakes by Individuals/Diet and Health Knowledge Survey(CSFII/DHKS)  

    Park, Sun-Min (Department of Food and Nutrition, College of Natural Science Hoseo University ) , Chern, Wen-S (Department of Agiculture Economics, The Ohio Sate University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 434 - 441 , 1997 , 0367-6463 ,

    초록

    Fat consumption has decreased since the 1950's in the United States, and coronary heart disease mortality rates have gradually declined as well. These changes might be associated with changes of attitudes due to increased information about the relationship between fat consumption and heart disease. The purpose of this study was to determine whether knowledge and attitudes concerning fat and foods high or low in fat had an impact on peoples' actual fat consumption. For this study, the data of fat consumption and knowledge/attitudes of people came from the 1989-1991 Continuing Survey of Food Intakes by Individuals/Diet and Health Knowledge Survey (CSFII/DHKS), conducted by USDA. It was found that women 65 years and older tried to avoid more fat and consume more vegetables than those aged 25-64 years : in fact, the actual fat consumption of those over 65 years was lowest among all age categories. However, the elderly did not have as much nutrition knowledge as people aged 25-64 years. Attitudes concerning vegetables and health were a better predictor of fat consumption than those concerning fat itself. However, low-fat milk consumption was influenced by nutrition knowledge as well as attitudes about fat intake : people with better knowledge and attitudes concerning fat intake consumed more low-fat milk. This could be resulted from the reason that low-fat milk is a good substitute for whole milk. The conclusion of this study is that there are two essential elements in healthy eating patterns : a) good attitudes towards fat and vegetable consumption, and b) correct nutritional knowledge concerning the fat-content of foods and the availability of alternatives.

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  8. [국내논문]   Conjugated Linoleic Acid Changes Fatty Acid Composition by Decreasing Monounsaturated Fatty Acids in Rabbits and Hep G2 Cells  

    Nam, Ki-Sun (Department of Nutritional Sciences Food Reasearch Institute University of Wisconsin-Madison)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 442 - 450 , 1997 , 0367-6463 ,

    초록

    Conjugated dienoic derivatives of linoleic acid(CLA) are a mixture of positional and geometric isomers of linoleic acid(LA). We previously found that CLA changes the fatty acid profile in chicken eggs and serum by decreasing monounsturated fatty acids. Studies were conducted to explore the effects of CLA on fatty acid composition. Rabbits were fed a semisynthetic diet with or without CLA(0.5g CLA/rabbit/day) for 22 weeks. Compared to the control, rabbits fed CLA had significantly lower monounsaturated fatty acid levels(palmitoleic acid C16 : 1 by 50% and olelc acid C18 : 1, by 20%) in plasma lipids. We found similar differences in fatty acid composition in the liver and the aorta. The inhibitory effect of CLA on $\Delta{9}$ desaturation was confirmed in a human hepatoma cell line, Hep G2. CLA significantly decreased $\Delta{9}$ desaturation in 4-5 hours as shown by an increase in the ratio of Cl6 : 0 to C16 : 1. This is apparently due to a decrease in $\Delta{9}$ desaturase(stearoyl-CoA desaturase, SCD) activity ; it was decreased more than 50%. These results, along with our previous findings, indicate that CLA is an inhibitor of $\Delta{9}$ desaturase in the liver.

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  9. [국내논문]   Effect of High Carbohydrate Intakes on the Obesity Index, Blood Pressure, and Blood Lipid Levels In Patients with Cardiovascular Disease  

    Lee, Seung-Min (Department of Home Economics Education, Chung-Ang University ) , Ahn, Hyang-Sook (Department of Home Economics Education, Chung-Ang University ) , Lee, Lil-Ha (Department of Home Economics Education, Chung-Ang University)
    韓國營養學會誌 = The Korean journal of nutrition. v.30 no.4 ,pp. 451 - 457 , 1997 , 0367-6463 ,

    초록

    This study was designed to investigate the effect of the ratio of energy from carbohydrate to total calories on dietary intake, obesity index, blood pressure, and blood lipid content in cardiovascular disease patients over 35 years old. A total of 552(227 male, 325 female) subjects were divided into three groups according to carbohydrate/total energy ratio : carbohydrate ratios below 25 percent were in the low carbohydrate group( $\geq{61.1}- ), and higher than 75 percent were in the high carbohydrate group( ${\geq}{74.7}%$ ). The anthropometric data, nutrient intake, serum lipid levels, and blood pressure of each group were compared with one another. For men and women with high carbohydrate intakes, inadequate nutritional intake was observed. Abdominal fat accumulation and blood TC level for men in the high carbohydrate group were higher than in medium or low carbohydrate groups. Therefore, It seems that high carbohydrate intake may produce adverse effects on abdominal fat accumulation and blood lipid patterns. Blood pressure, however, was significantly higher for women in low and high carbohydrate groups than in medium carbohydrate group. These results suggest that extremely high and low carbohydrate intake may raise the risk of cardiovascular disease and that it is necessary to consume nutritionally balanced meals. This can be done by controlling the ratio of dietary carbohydrate at a medium level in order to prevent and/or to reduce the risk.

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